Protein Alignment msi and DAZL

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001177740.1
• Gene: DAZL / 1618
• HGNCID: 2685
• Length: 315
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 59/263 - (22%)
• Similarity: 92/263 - (34%)
• Gaps: 96/263 - (36%)

  Fly   177 GGSNKSGSSGRSTPSLSGGSGSDP-APGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVT 240
            ||..|:    |.||||...|.::| .|........|.|:||                       .
Human     7 GGDRKA----RLTPSLPHESTANPETPNSTISREASTQSSS-----------------------A 44

  Fly   241 QRSRGFGFITFQEPCTVEKVLKVPIHTLDGKKIDPKHATPKNRPRQANKTKKIFVGGVSQDTSAE 305
            ..|:|:                    .|...||.|               ..:||||:.......
Human    45 ATSQGY--------------------ILPEGKIMP---------------NTVFVGGIDVRMDET 74

  Fly   306 EVKAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFENEDVVDRVCE--IHFH--------TIKNKK 360
            |::::|:::|.|:|..::.| :|...:|:|||:|.|:..|.::.|  |:||        .|:.:.
Human    75 EIRSFFARYGSVKEVKIITD-RTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQN 138

  Fly   361 VECKKAQPKEAV---TPAAQLLQKRIMLGTLGVQLPTAPGQLIGARGAGVATMNPLAMLQNPTQL 422
            :.....||:..|   .|..|.........|.....||             .||||:      ||.
Human   139 LCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPT-------------TTMNPI------TQY 184

  Fly   423 LQS 425
            :|:
Human   185 VQA 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	10/73 (14%)
		RRM2_MSI	292..365	CDD:240769	23/82 (28%)
DAZL	NP_001177740.1	RRM_DAZL	55..136	CDD:410073	26/96 (27%)
		PABP-1234	<60..228	CDD:130689	38/148 (26%)