Protein Alignment msi and msi2a

DIOPT Version :9

• Sequence 1: NP_001247303.1
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: XP_009303812.1
• Gene: msi2a / 100002680
• ZFINID: ZDB-GENE-030826-25
• Length: 407
• Species: Danio rerio
• Alignment Length: 439
• Identity: 165/439 - (37%)
• Similarity: 219/439 - (49%)
• Gaps: 64/439 - (14%)

  Fly   192 LSGGSGSDPA--PGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEP 254
            ::.||.:|..  |||:|:||||||||.|.|::||..||.:.:.::|:||.|:||||||||||.:.
Zfish     8 VTSGSLNDSQHDPGKMFIGGLSWQTSPDSLRDYFCKFGEIRECMVMRDPTTKRSRGFGFITFADV 72

  Fly   255 CTVEKVLKVPIHTLDGKKIDPKHATPKN-RPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVE 318
            .:|:|||..|.|.||.|.||||.|.|:. :|:...:||||||||:|..|..|:||.||.|||.||
Zfish    73 SSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSASTVVEDVKQYFEQFGKVE 137

  Fly   319 ETVMLMDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRI 383
            :.:::.|:.|.||||||||||||||:|::|||||||.|.||.||||||||||.:.|.....:.|.
Zfish   138 DAMLMFDKTTNRHRGFGFVTFENEDIVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARS 202

  Fly   384 MLGT-----LGVQLPTAPGQLIGARGAGVATMNPLAMLQNPTQLLQSPAAAAAAQQAALISQNPF 443
            :..|     ||:.:.:.| .::...|.|....:|....|.|    ..||.|.....||
Zfish   203 LPYTMDAFMLGMGMLSYP-NIVATYGRGYTGFSPSYSYQFP----GFPATAYGPVAAA------- 255

  Fly   444 QVQNAAAAASIANQAGFGKL-LTTYPQTALHSV-RYAPYSIPASAATANAALMQAHQAQSVAAAA 506
                |.|||..:.:|..|:. ...|||.|.... .|..||.|.....|..:.     |.......
Zfish   256 ----AVAAARGSGRATRGRSGYMAYPQNAGPGFPDYGFYSGPGDQRAAPCSF-----ADYATLGP 311

  Fly   507 HHHQQQQQQQHHHQQQTHNAHVAAAQQQQQSHHNAVSNPASQAHSAAAAAALAANAANGAGAAGA 571
            |..|..|.:           ||.:.......||      .|..|..::    .||.....|..||
Zfish   312 HTGQMLQSE-----------HVTSTCNSPSQHH------PSPDHFKSS----GANPPRPGGFPGA 355

  Fly   572 HSLAAAAQQAG-----LMAGNPLNAAAAAAAAAANP-------AAAYSN 608
            :|....|...|     ...||.::||:....:..|.       |.|::|
Zfish   356 NSPGPVADLYGPSSQDSAVGNYISAASPQPGSGFNHSIAGPLIATAFTN 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	40/70 (57%)
		RRM2_MSI	292..365	CDD:240769	48/72 (67%)
msi2a	XP_009303812.1	RRM	<2..162	CDD:223796	85/153 (56%)
		RRM1_MSI	23..97	CDD:241020	42/73 (58%)
		RRM2_MSI	111..184	CDD:240769	48/72 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579358
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000417
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101082
Panther	1	1.100	-	-	O	PTHR48032
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X310
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.740