DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4582 and Pnliprp1

DIOPT Version :9

Sequence 1:	NP_651403.1	Gene:	CG4582 / 43086	FlyBaseID:	FBgn0039344	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_114470.1	Gene:	Pnliprp1 / 84028	RGDID:	620792	Length:	473	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	91/338 - (26%)
Similarity:	141/338 - (41%)	Gaps:	54/338 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 TAAFGLNVMNKGDQEQNQQF---TSE------PVNLYDAASLRRSRFSPFNPTRILIHGWLGNEN 177
            ||...|.::....::.|.:|   |:|      .:.|.|..::..|.|.....||.:|||::....
  Rat    37 TAIRPLKLLPWSPEKINTRFLLYTNENPTAFQTLQLSDPLTIGASNFQVARKTRFIIHGFIDKGE 101

  Fly   178 ANMYNELLPAYFDLRNGNYNIFTVDWGRGAIADYITASYRVKPVGQVLAKFVDFLHQEAGMRFED 242
            .|...::....|.:.  ..|...|||.:|:...|..|:..|:.||..:|:.:|.|.:........
  Rat   102 ENWVVDMCKNMFQVE--EVNCICVDWKKGSQTTYTQAANNVRVVGAQVAQMIDILVKNYSYSPSK 164

  Fly   243 LQLVGFSMGAHVAGLAGKHLQTGRLRMIRALDPALPFFRYAKPKERLTAEDADYVEVLHTSVG-- 305
            :.|:|.|:||||||.||.  :|..|..|..|||....|.....:.||...|||:|:|:||...
  Rat   165 VHLIGHSLGAHVAGEAGS--RTPGLGRITGLDPVEANFEGTPEEVRLDPSDADFVDVIHTDAAPL 227

  Fly   306 ----SYGFDRPVGHVDFYANWGSQQPGC-------------FWH------ECSHWRAFMLFAESL 347
                .:|.::..||:||:.|.|...|||             .|.      .|:|.|::..:.||:
  Rat   228 IPFLGFGTNQMSGHLDFFPNGGQSMPGCKKNALSQIVDIDGIWSGTRDFVACNHLRSYKYYLESI 292

  Fly   348 ARDQATGFLSQGCPAAEWQQLTRFHRCPKDTGVMQTMGGDLANVSAEFLAQRQGVYYFQTNDQPP 412
            ....  ||.:..|.:.:..:..:...|| |.|..| ||.     .|:..|.:.|       |:|.
  Rat   293 LNPD--GFAAYPCASYKDFESNKCFPCP-DQGCPQ-MGH-----YADKFAGKSG-------DEPQ 341

  Fly   413 YVLAQNASSKRAA 425
            ........:|..|
  Rat   342 KFFLNTGEAKNFA 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4582	NP_651403.1	Pancreat_lipase_like	138..409	CDD:238363	84/304 (28%)
Pnliprp1	NP_114470.1	Lipase	18..353	CDD:395099	90/335 (27%)
Pnliprp1	NP_114470.1	PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338969
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840