Protein Alignment CG4582 and PNLIPRP1

DIOPT Version :10

• Sequence 1: NP_651403.1
• Gene: CG4582 / 43086
• FlyBaseID: FBgn0039344
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_006220.1
• Gene: PNLIPRP1 / 5407
• HGNCID: 9156
• Length: 467
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 84/300 - (28%)
• Similarity: 135/300 - (45%)
• Gaps: 40/300 - (13%)

  Fly   141 FTSEPVN------LYDAASLRRSRFSPFNPTRILIHGWLGNENANMYNELLPAYFDLRNGNYNIF 199
            :|:|..|      |.|.:::..|.|.....||.:|||::...:.:...::....|::.  ..|..
Human    59 YTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVE--EVNCI 121

  Fly   200 TVDWGRGAIADYITASYRVKPVGQVLAKFVDFLHQEAGMRFEDLQLVGFSMGAHVAGLAGKHLQT 264
            .|||.:|:.|.|..|:..|:.||..:|:.:|.|..|.......:.|:|.|:||||||.||.  :|
Human   122 CVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGS--KT 184

  Fly   265 GRLRMIRALDPALPFFRYAKPKERLTAEDADYVEVLHTSVG------SYGFDRPVGHVDFYANWG 323
            ..|..|..|||....|.....:.||...|||:|:|:||...      .:|.::.:||:||:.|.|
Human   185 PGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPNGG 249

  Fly   324 SQQPGC-------------FWH------ECSHWRAFMLFAESLARDQATGFLSQGCPAAEWQQLT 369
            ...|||             .|.      .|:|.|::..:.||:....  ||.:..|.:.:..:..
Human   250 ESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPD--GFAAYPCTSYKSFESD 312

  Fly   370 RFHRCPKDTGVMQTMGGDLANVSAEFLAQRQGVYYFQTND 409
            :...|| |.|..|.  |..|:..|...::.|..::..|.:
Human   313 KCFPCP-DQGCPQM--GHYADKFAGRTSEEQQKFFLNTGE 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4582	NP_651403.1	Pancreat_lipase_like	138..409	CDD:238363	84/298 (28%)
PNLIPRP1	NP_006220.1	Lipase	18..353	CDD:395099	84/299 (28%)
		PLAT_PL	356..467	CDD:238857