Protein Alignment CG5111 and Nub1

DIOPT Version :10

• Sequence 1: NP_651402.1
• Gene: CG5111 / 43085
• FlyBaseID: FBgn0039343
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_063141761.1
• Gene: Nub1 / 296731
• RGDID: 1359489
• Length: 621
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 180/648 - (27%)
• Similarity: 306/648 - (47%)
• Gaps: 89/648 - (13%)

  Fly     1 MSQINNIFIKLRARLRERDIKLWEEPYYFEEVGSIESEMDRLARDISGELGISVSDCRIALGELQ 65
            |:|...:..||...|||..|:||:.| |.||...:...:..||:..|..|....::....:.|::
  Rat     9 MAQKKYLQAKLTQFLREDRIQLWKPP-YTEENKEVGLALKDLAKRYSERLECCENEVENIIEEIR 72

  Fly    66 DGALRKLAARREFNDTGLATFNVRC-----VDSKGGTVQMLEIKCSLGGLGSDLQAEVAKKLDIV 125
            ..|:.:......:..||:||..|..     .|.|    .:||.:  |...|.||::::|:....
  Rat    73 CKAIERGTGNEHYRTTGIATIEVFLPPRLRKDKK----SLLETR--LHVTGRDLRSKIAETFGF- 130

  Fly   126 DSSHVKCISGGRIINGQKTLASQGLKTNQHLMVV----------------VGGTNEGQELHERIQ 174
            ..:::|.:...:.:...|:|..||:..|...||:                ....||.::..:|||
  Rat   131 QENYIKIVINKKQLQLGKSLEEQGVTHNVKAMVLELKQSEEDVRRNLQLEEEEQNEAEQKEKRIQ 195

  Fly   175 RIRADLELVADADR---------FMEMEDQDGRPIFLPREENRSLLMAMSMYEVARVAMHKENFD 230
            |.:..||::|:...         ::::.:|.||.|.:|..|.::|::||..:|..|..:.::.:.
  Rat   196 RTKRGLEILAERAEMVVDPETMPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYG 260

  Fly   231 EALLILLEADELFSQCDSKLLEGVDNYALINLDIVWCYLRLKNITQLPDAQRRLDICERGFVKSY 295
            .||..||:||..|.:| .:||:.|||||::.|||||||.||:.:..|.||:::|::.:..|...|
  Rat   261 IALPCLLDADRYFCEC-KELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQTCFTNCY 324

  Fly   296 GEQFIRLFSIKGPSSPERALIMRLHLLQGVLLFHQNRRDEAYEKLEVATKDLYEVKMNDTELSTL 360
            ||...||.:|||....|:.|.:||:||||:..:|....:||.|.|..|.:...|:.::.:::..|
  Rat   325 GENHQRLVNIKGNCGKEKVLFLRLYLLQGIRNYHSGNGEEAREYLNKARQLFKELYIDPSKVHNL 389

  Fly   361 VEMGYEESDARLALRSCAGQVDRAIQYIQERSERISEERKNSAAERQVNQEMIFAGQGGEWVNPR 425
            :::|:...:|||.||:|.|.||.|..:|..|.|.:::.||....:|:...|
  Rat   390 LQLGFTAQEARLGLRACDGNVDHAATHISNRREELAQIRKEEKEKRKRRLE-------------- 440

  Fly   426 SIIRLMEMGYERRLVVEALKRTKNNLDRSLDLLQRH-------SDELRANLPPIPPVDESLLTTL 483
            |:..|..|||..:...:||.:.:.|||.:|.:|..:       ..:...|.....|..|| :..|
  Rat   441 SVNTLRGMGYSTQAAKQALHQARGNLDDALKILLSNPHMWWLQDSDSENNSRQASPSQES-IDQL 504

  Fly   484 QHLGFSEISARDALETTGNSFHKSLKFLLK---SFPNESELLHVIETMTKVLEVQEPTSSTNATA 545
            .::||..:.|..||.....:...:.:.|..   |.|.:.:.            ..|.:|||
  Rat   505 VYMGFDTVVAEAALRVFAGNVQLAAQTLAHHGGSLPPDLQF------------SGEDSSST---- 553

  Fly   546 NSTTPLVNLSNSKVNLLQTVLSEAKSEIESYNAFKRFNENLAENNNHYLNLPLDQEEQILIEY 608
            .||:|..:...|..:..:.:.:||.:||         .|::.|:...||:..|:.||.|:.||
  Rat   554 PSTSPSDSAGTSSASTDEDMETEAVNEI---------LEDIPEHEEDYLDSTLEDEEVIIAEY 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5111	NP_651402.1	Ubl_NUB1	82..160	CDD:340582	21/98 (21%)
		UBA1_NUB1_like	353..388	CDD:270477	12/34 (35%)
		UBA2_UBP13	424..458	CDD:270570	11/33 (33%)
		rad23	<427..>533	CDD:273167	24/115 (21%)
Nub1	XP_063141761.1	None