DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5112 and TOC64-III

DIOPT Version :9

Sequence 1:	NP_651400.1	Gene:	CG5112 / 43083	FlyBaseID:	FBgn0039341	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_188424.2	Gene:	TOC64-III / 819660	AraportID:	AT3G17970	Length:	589	Species:	Arabidopsis thaliana

Alignment Length:	432	Identity:	92/432 - (21%)
Similarity:	159/432 - (36%)	Gaps:	85/432 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 PFLGVPFSTKDSTAVAGRLHTLGL--LARKSERSTTDAECVRLMKESGAIIIATSNVPEVNKWIE 183
            |..|:.|:..|...:.|.:...|.  ..|..|.:::.:..|..:.|.||..:..:.|.|....|.
plant    57 PLTGLTFAVSDVFDITGYVTGFGHPDWVRTHEAASSTSPVVSTLVEGGATCVGKTVVDEFAFSIS 121

  Fly   184 SRNMLIGCTNNPYDLRRSVGGSSGGEAALIAACCTGFGLGTDIGGSIRIPAFNCGIFGHKPTSGA 248
            ..|.......||....|..||:..|.|..:|.....|.||.|..|.:|:||..||:.|.|.:.||
plant   122 GENKHYDSPTNPAAPTRIPGGACSGAAVAVATNAVDFALGIDTVGGVRVPAGYCGVLGFKSSYGA 186

  Fly   249 VNMAGCTFRTGKEKDTMVCAGPMSRS-------ARDLLPMMQVLVEPSLKAKLKLDQKVDLKRLR 306
            ::..|..              |:|.|       |||          |:           .|:|:.
plant   187 ISNTGII--------------PVSSSLDSVGWFARD----------PN-----------TLRRVG 216

  Fly   307 YFYVSSNGMAQCNP------------INRETERVMYKIRKHFEAVSGKD-VRHADLP---YTKLT 355
            :..:......|.||            :....:|:...:.|..|.:.|:. ::|.:|.   .||:.
plant   217 HVLLQLPFATQRNPRQIILADDCFQLLKIPVDRITQVVTKSAEKLFGRQLLKHQNLETYFETKVP 281

  Fly   356 GKMWRYWMTQEPANFNL----LLGNGAELNPFVELFKKILGQSDYSMAAIYGLIDSVLPK---EK 413
             .:..:..|:..||..:    ||.|..:|   ::..:.:....|: :..:...||.|:..   |.
plant   282 -SLKEFARTKAIANTKVSTSRLLANVMQL---LQRHEFLQNHGDW-INTVKPAIDPVILSQVCEN 341

  Fly   414 EKLMREATA-------KCKKSVQDLLGDDGVLFFHSSPRTAPFHYYPLVKFNDF-----AYFSLF 466
            .:|..|.|.       :.:.::..||.|||:|...:.|...|......:...|:     :..|:.
plant   342 PELTNEETENLNAIRNETRVAIGSLLKDDGILVIPTLPAVPPKLGSKEITSEDYQNRASSLLSIA 406

  Fly   467 NVLHLPATQVPMGLDSKGMPLGIQVVANPNNDRLCLAVAEEL 508
            ::.......||:|...| .|:.:..:.....||..|...:.:
plant   407 SISGCCQVTVPLGHHEK-CPISVSFIGRHGGDRFLLDTVQTM 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5112	NP_651400.1	PRK07488	52..513	CDD:236030	92/432 (21%)
CG5112	NP_651400.1	Amidase	69..502	CDD:302749	91/424 (21%)
TOC64-III	NP_188424.2	Amidase	33..451	CDD:418511	92/432 (21%)
		3a0801s09	463..>588	CDD:273380
		TPR repeat	474..502	CDD:276809
		TPR repeat	507..537	CDD:276809
		TPR repeat	542..569	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810