Protein Alignment CG5112 and faah-1

DIOPT Version :9

• Sequence 1: NP_651400.1
• Gene: CG5112 / 43083
• FlyBaseID: FBgn0039341
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_501368.1
• Gene: faah-1 / 177613
• WormBaseID: WBGene00015047
• Length: 572
• Species: Caenorhabditis elegans
• Alignment Length: 608
• Identity: 149/608 - (24%)
• Similarity: 236/608 - (38%)
• Gaps: 155/608 - (25%)

  Fly     7 VLDALLALVHILSDR-----LLEFVLDWYLGEHKRVSGPPSLEQQTTITKSAVEL---------- 56
            ||.|:...||..::|     .||.|     .:.:|.....::||   ..|:|.:|
 Worm     9 VLGAIAFYVHFSNNRKKLIERLEIV-----AQRRRDDLSKNVEQ---ARKAADKLDTQRRDWIGS 65

  Fly    57 --AQQIRERRQRSY----DIVKAYCERIESVNRDLNAV----VDGPFPEALDQAREIDRKLDEKE 111
              .:|:|:..||.:    :.::||..:....:...|||    :|     |..||.|:|.:.....
 Worm    66 LDFEQLRDELQRGHVTCVEAIRAYFHKAILAHEKTNAVTCFILD-----AERQAEELDEQAKLPY 125

  Fly   112 YSDEDLRRLPFLGVPFSTKDSTAVAGRLHTLGLLARKSERSTTDAECVRLMKESGAIIIATSNVP 176
            |.     :.|..|||.|.|:...|.|...|.|.:......:|.|:..|...|:.|.|....:|||
 Worm   126 YV-----KPPLFGVPLSLKECLKVKGYDTTRGFVQDAYHPATEDSIQVEHYKKLGLIPFCQTNVP 185

  Fly   177 EVNKWIESRNMLIGCTNNPYDLRRSVGGSSGGEAALIAACCTGFGLGTDIGGSIRIPAFNCGIFG 241
            :........|.|.|.|.||||..|:.|||||||.|||.|..:..|:|||:|||:|||....|..|
 Worm   186 QSLLSYNCSNPLFGTTTNPYDSTRTCGGSSGGEGALIGAGGSLIGIGTDVGGSVRIPCHFTGTAG 250

  Fly   242 HKPT-------SGAVNMAGCTFRTGKEKDTMVCAGPMSRSARDLLPMMQVLVEPSLKAKLKLDQK 299
            .||:       .|..::.|.......:       |||::..:..:..::     ::...:.....
 Worm   251 IKPSKMRFAHRGGGASVPGKPLIDAND-------GPMAKDVKTNVEFLR-----NVWGDIDFQSD 303

  Fly   300 VD---------------LKRLRYFYVSSNGMAQCNPINRETERVMYKIRKHFEAVSGKDVRHADL 349
            .|               .|:||..|...:|.....|   ..:|.:.:.:||.||..     |..:
 Worm   304 RDPYCPPVHWNESVYSSEKKLRVGYYIDDGWFTPTP---ALQRAVLESKKHLEAAG-----HTVI 360

  Fly   350 PY--TKLTGKMWRYWMTQEPANFNLLLGNGAE--LNPFVELFKKILGQS---------------- 394
            |:  .:|...|..|        |..:..:|.:  ||   :|.|.|:..:
 Worm   361 PFYPPRLPSVMQLY--------FRAVCLDGGQYVLN---KLLKDIIEPTIRFQVTLWMVPVWIQR 414

  Fly   395 --DYSMAAIY---GLIDSVLPKEKEKLMREATAKCKKSVQDLLG----DD-GVLFFHSSPRTAPF 449
              .|.::.::   |::...|.::..:| |||.|..:...::.:|    |: .|:...:|...||.
 Worm   415 ILSYPVSLVFPRMGMLMQSLTRDTFEL-REAYADIEAYREEFVGLMMKDNLDVILCPASIMPAPQ 478

  Fly   450 HYYPLVKFNDFAYFSLFNVLHLPATQVPMGLDSK----------------------------GMP 486
            |..|....:..:|..|:|:|...|..||:...||                            |||
 Worm   479 HDIPSKVVSGVSYTCLYNLLDFGAGVVPVTAVSKSDEEKLINEYPETDKWYQITKKATLGAVGMP 543

  Fly   487 LGIQVVANPNNDRLCLAVAEELE 509
            :|:||.|.|..:...|....|:|
 Worm   544 IGVQVAAPPYREEAVLRTMREIE 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5112	NP_651400.1	PRK07488	52..513	CDD:236030	136/558 (24%)
		Amidase	69..502	CDD:302749	127/516 (25%)
faah-1	NP_501368.1	Amidase	84..559	CDD:279733	127/516 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D852596at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101248
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1914
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850