Protein Alignment CG5112 and FAAH2

DIOPT Version :10

• Sequence 1: NP_651400.1
• Gene: CG5112 / 43083
• FlyBaseID: FBgn0039341
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_777572.2
• Gene: FAAH2 / 158584
• HGNCID: 26440
• Length: 532
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 210/526 - (39%)
• Similarity: 312/526 - (59%)
• Gaps: 23/526 - (4%)

  Fly    13 ALVHILSDRLLEFVLDWYLGEHKRVSGPPSLEQQT--TITK-----SAVELAQQIRERRQRSYDI 70
            |.:.:...|.|.|::. .:|....|.|.|....:|  .:|:     |.::||:.||:|:.:..|:
Human     7 ARIQLFLLRALGFLIG-LVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDV 70

  Fly    71 VKAYCERIESVNRDLNAVVDGPFPEALDQAREIDRKLDEKEYSDEDL-RRLPFLGVPFSTKDSTA 134
            |:||..||:.||..:|.:|...|.||:.:|..:|:||.||:..:..| .:.||||||.:.|::..
Human    71 VQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFLGVPLTVKEAFQ 135

  Fly   135 VAGRLHTLGLLARKSERSTTDAECVRLMKESGAIIIATSNVPEVNKWIESRNMLIGCTNNPYDLR 199
            :.|..::.||:.|:...:.|||..|.|:|.:|||.:..:|..|:..|.||.|.:.|.:||||||:
Human   136 LQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDLQ 200

  Fly   200 RSVGGSSGGEAALIAACCTGFGLGTDIGGSIRIPAFNCGIFGHKPTSGAV-NMAGCTFRTGKEKD 263
            ..||||||||...:||.|:..|:|:|||||||:|||..|||||||:.|.| |........|.: :
Human   201 HIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQ-E 264

  Fly   264 TMVCAGPMSRSARDLLPMMQVLVEPSLKAKLKLDQKVDLKRLRYFYVSSNGMA-QCNPINRETER 327
            ..:|.|||.|.|.||.||::|:..|.:| :||||.||.||.|:::::..:|.: ..:.::::...
Human   265 LFLCTGPMCRYAEDLAPMLKVMAGPGIK-RLKLDTKVHLKDLKFYWMEHDGGSFLMSKVDQDLIM 328

  Fly   328 VMYKIRKHFEAVSGKDVRHADLPYTKLTGKMWRYWMT------QEPANFNLLLG-NGAELNPFVE 385
            ...|:..|.|.:.|..|:|..|...|.:.::|...|:      :||..|..||| :|..::|..|
Human   329 TQKKVVVHLETILGASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWE 393

  Fly   386 LFKKILGQSDYSMAAI-YGLIDSVL--PKEKEKLMREATAKCKKSVQDLLGDDGVLFFHSSPRTA 447
            |.|..||.|.|::.:| ..|::..|  ..||.:..:......:|.:.|:||||||..:.|.|..|
Human   394 LIKWCLGLSVYTIPSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVA 458

  Fly   448 PFHYYPLVKFNDFAYFSLFNVLHLPATQVPMGLDSKGMPLGIQVVANPNNDRLCLAVAEELERTF 512
            |.|:.||.:..:|||..:|:.|.||.||.|:||::||:||||||||.|.||.|.||||:.||:||
Human   459 PKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTF 523

  Fly   513 GGWVPP 518
            ||||.|
Human   524 GGWVCP 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5112	NP_651400.1	GatA	50..520	CDD:439924	201/487 (41%)
FAAH2	NP_777572.2	GatA	45..524	CDD:439924	195/480 (41%)