DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5112 and AgaP_AGAP001699

DIOPT Version :9

Sequence 1:	NP_651400.1	Gene:	CG5112 / 43083	FlyBaseID:	FBgn0039341	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	XP_321392.5	Gene:	AgaP_AGAP001699 / 1281476	VectorBaseID:	AGAP001699	Length:	559	Species:	Anopheles gambiae

Alignment Length:	520	Identity:	177/520 - (34%)
Similarity:	271/520 - (52%)	Gaps:	43/520 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VLDWYLGEHKR-VSG-------PPSLEQQTTITKSAVELAQQIRERRQRSYDIVKAYCERIESVN 82
            |..|::..:.: |||       ||.  :...:..||..||::||:|..||.|:|:||.:|.:.||
Mosquito    55 VFSWFVMPYSQCVSGRIERRKLPPI--EDPLLLLSATVLAERIRKREIRSEDVVRAYIQRCQQVN 117

  Fly    83 RDLNAVVDGPFPEALDQAREIDRKLDEKEY--SDEDLRRLPFLGVPFSTKDSTAVAGRLHTLGLL 145
            ..|||:|:..|..||::|:|:||:|.:...  ::|..|..|.||:|.|.|:|.||.|..:|.|..
Mosquito   118 PLLNAIVEDRFEAALEEAQEVDRQLAKGTLGPAEELARTKPLLGLPVSIKESLAVEGMSNTAGRK 182

  Fly   146 ARKSERSTTDAECVRLMKESGAIIIATSNVPEVNKWIESRNMLIGCTNNPYDLRRSVGGSSGGEA 210
            .|:.:.:.:||..|..:|.:|.|::..||.||:....|:.|...|.|.|||:|:|:.||||||||
Mosquito   183 LREKKVALSDAPVVHQIKRAGGIVLLVSNTPELCLCWETYNQCTGLTRNPYNLQRTAGGSSGGEA 247

  Fly   211 ALIAACCTGFGLGTDIGGSIRIPAFNCGIFGHKPTSGAVNMAG----CTFRTGKEKDTMVCAGPM 271
            |||||..:..|:.|||.||.|:||...|:|||||:...|:..|    |   ..:...:....|.|
Mosquito   248 ALIAAAGSLLGVTTDIAGSSRLPAMFTGVFGHKPSPYVVSPYGHHPSC---DDENWGSFFTPGAM 309

  Fly   272 SRSARDLLPMMQVLVEPSLKAKLKLDQKVDLKRLRYFYVSSNG-MAQCNPINRETERVMYKIRKH 335
            .|.|.||..:::.:.:|. ...:.|.:.|.:..|:.:|:.::| .....||:.:..:.:..:..|
Mosquito   310 CRYAEDLPLLLEAMRDPE-GTPVTLHKPVPIGALKCYYMENDGPSGLTRPIDADIVQAIRDVAAH 373

  Fly   336 FEA--VSGKDVRHA-DLPYTKLTGKMWRYWMTQEPANFNLLLGNGAELNPFV----ELFKKILGQ 393
            ..|  |:.|.:|.. |:...|:.          ...|...:....|...|..    |:||.:||.
Mosquito   374 LNAQRVNLKRLRWTLDISVCKML----------RMKNVETIYSPQANGKPDTTMKREVFKYLLGM 428

  Fly   394 SDYSMAAI-----YGLIDSVLPKEKEKLMREATAKCKKSVQDLLGDDGVLFFHSSPRTAPFHYYP 453
            |...:.::     ..::::.:|:.:...:...|.|.:|...||||.|||..:...|.||..||..
Mosquito   429 SKSDLPSVMIGPMQHIVNNYIPQSRLDFLDAQTEKLRKDFIDLLGTDGVFIYPGFPNTAHRHYRI 493

  Fly   454 LVKFNDFAYFSLFNVLHLPATQVPMGLDSKGMPLGIQVVANPNNDRLCLAVAEELERTFGGWVPP 518
            ..|..|..|..:||.:.|||....:|.|.:.:|:|:|:||.|..|.|..|||:||||.|||||.|
Mosquito   494 FHKLVDTTYMMVFNTVGLPAASCMVGFDREKLPIGVQIVAAPGQDHLIFAVAKELERRFGGWVAP 558

Fly 519 518
Mosquito 559 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5112	NP_651400.1	PRK07488	52..513	CDD:236030	164/479 (34%)
CG5112	NP_651400.1	Amidase	69..502	CDD:302749	148/451 (33%)
AgaP_AGAP001699	XP_321392.5	GatA	80..558	CDD:223232	169/491 (34%)
AgaP_AGAP001699	XP_321392.5	PRK07488	80..553	CDD:236030	164/486 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D852596at2759
OrthoFinder	1	1.000	-	-		FOG0002245
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X256
TreeFam	0	0.000	Not matched by this tool.
	4	3.920