DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5112 and AgaP_AGAP011315

DIOPT Version :9

Sequence 1:	NP_651400.1	Gene:	CG5112 / 43083	FlyBaseID:	FBgn0039341	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	XP_309335.4	Gene:	AgaP_AGAP011315 / 1270620	VectorBaseID:	AGAP011315	Length:	537	Species:	Anopheles gambiae

Alignment Length:	532	Identity:	211/532 - (39%)
Similarity:	303/532 - (56%)	Gaps:	38/532 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ALLALVHILSDRLLEFVLDW----YLGEH-KRVSGPPSLEQQTTITKSAVELAQQIRERRQRSYD 69
            :||..|..:..:.|..::.|    ..||| ||:  ||.  ....:.:||..||.:||.|:..|.:
Mosquito    17 SLLKTVINVGHKFLVLLVRWLSRTIYGEHGKRM--PPI--TNLILMESATSLATKIRTRKLTSVE 77

  Fly    70 IVKAYCERIESVNRDLNAVVDGPFPEALDQAREIDRKLDEKEYSDEDL-RRLPFLGVPFSTKDST 133
            :.:|:.:|...||..||.|||..|..||..|...|:.:.....:.|.| |..||||||.||||..
Mosquito    78 VTQAFIDRCREVNPLLNCVVDERFEAALKDAERADKLIASGTMTVEQLEREKPFLGVPISTKDCI 142

  Fly   134 AVAGRLHTLGLLARKSERSTTDAECVRLMKESGAIIIATSNVPEVNKWIESRNMLIGCTNNPYDL 198
            .|.|.|||.|:..|::.|...||..:.||:.:|||..|.:||.|...| ||.|.:.|.:.||||.
Mosquito   143 RVEGLLHTSGIWNRRNIRGDKDARAMELMRRAGAIPFALTNVSECCMW-ESVNTIHGRSRNPYDA 206

  Fly   199 RRSVGGSSGGEAALIAACCTGFGLGTDIGGSIRIPAFNCGIFGHKPTSGAVNMAG-CTFRTGKEK 262
            .|.||||||||..:.||..:.||||:|||||||:|||..||||||||...|:..| ......:|:
Mosquito   207 NRIVGGSSGGEGCIQAAAASPFGLGSDIGGSIRMPAFFNGIFGHKPTKFVVSNEGQYPVALSEEQ 271

  Fly   263 DTMVCAGPMSRSARDLLPMMQVLVEPSLKAKLKLDQKVDLKRLRYFY-VSSNGMAQCNPINRETE 326
            ::.:..|||.|.|.||.||::::.:.: ..||:||:.||||::::|| ::..|....:|::.:..
Mosquito   272 NSFLGIGPMCRYATDLKPMLRIIADEN-APKLRLDEPVDLKQVKFFYQINDGGAHLVSPVDLDIR 335

  Fly   327 RVMYKIRKHFEAVSGKDVRHADLPYTKLTGKMWRYWM-TQEPANFNLLLGN--GAELNPFVELFK 388
            ..|.|:..||.|....:|:...|...:.:..||...| |.....|:..|.|  || :||::||.|
Mosquito   336 DAMEKVMAHFRATVKAEVKKVYLDKLRKSAPMWLANMKTPSKVGFDSQLANLEGA-INPWLELAK 399

  Fly   389 KILGQSDYSMAAI-----------YGLID-SVLPKEKEKLMREATAKCKKSVQDLLGDDGVLFFH 441
            ..|..|::::..|           ||..: ....::|::|:.|        .:|:||::||..:.
Mosquito   400 WPLRMSNHTLIGILTALTERGGVKYGSAEYHHYVQQKQELVSE--------FRDMLGENGVFIYP 456

  Fly   442 SSPRTAPFHYYPLVKFNDFAYFSLFNVLHLPATQVPMGLDSKGMPLGIQVVANPNNDRLCLAVAE 506
            :.|..||:|..||::..:|:|.::.|||.||||.||:||..:|:|:|:||||..|.||||||||.
Mosquito   457 THPTVAPYHNEPLIRALNFSYTAIINVLGLPATAVPLGLGREGLPVGLQVVAGVNQDRLCLAVAC 521

  Fly   507 ELERTFGGWVPP 518
            ||||.|||||.|
Mosquito   522 ELERAFGGWVAP 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5112	NP_651400.1	PRK07488	52..513	CDD:236030	193/478 (40%)
CG5112	NP_651400.1	Amidase	69..502	CDD:302749	176/450 (39%)
AgaP_AGAP011315	XP_309335.4	PRK07488	60..528	CDD:236030	193/478 (40%)
AgaP_AGAP011315	XP_309335.4	Amidase	77..517	CDD:302749	176/450 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D54749at33392
OrthoFinder	1	1.000	-	-		FOG0002245
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X256
TreeFam	0	0.000	Not matched by this tool.
	5	4.820