DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5112 and faah.1

DIOPT Version :9

Sequence 1:	NP_651400.1	Gene:	CG5112 / 43083	FlyBaseID:	FBgn0039341	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	XP_012817045.1	Gene:	faah.1 / 100487591	XenbaseID:	XB-GENE-5837110	Length:	586	Species:	Xenopus tropicalis

Alignment Length:	587	Identity:	140/587 - (23%)
Similarity:	235/587 - (40%)	Gaps:	138/587 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LALVHILSDRLLEFVLDWYLGEHKRVSGPPSLEQQTTITKSAVELAQQIRERRQRSYDIVKAYCE 76
            |..:|.|.  |::..:..:..:|      |.::....::.:..:|..|:::....:...:.||.|
Frog    50 LQRLHALD--LMQKTISQFKKQH------PDVDTGHIVSLTLSQLVDQLKKGSLTAESALIAYTE 106

  Fly    77 RIESVNRDLNAVVDGPFPEALDQAREIDRKLDEKEYSDEDLRRLPFLGVPFSTKDSTAVAGRLHT 141
            :...||::||.:.|. ..|...|.:|:      |:..::.|    ..|||.:.||:....|....
Frog   107 KALEVNKELNCLTDF-LSECEAQLQEV------KKQKEKGL----LYGVPITLKDNVGYKGHDSH 160

  Fly   142 LGLLARKSERSTTDAECVRLMKESGAIIIATSNVPEVNKWIESRNMLIGCTNNPYDLRRSVGGSS 206
            .||:.........|:..|:::|:.||:....:|:|:.....:..|.:.|.|.||::.:::.||||
Frog   161 CGLVQFLGIVDQEDSVIVQVLKKQGAVPFVKTNIPQSMINFDCSNSIFGQTLNPHNHKKTCGGSS 225

  Fly   207 GGEAALIAACCTGFGLGTDIGGSIRIPAFNCGIFGHKPTSGAVNMAGCTFRTGKEKDTMVCAGPM 271
            ||||||||......|:|||:.||||:|...|||.|.||:...::..|.:......|..::..|||
Frog   226 GGEAALIAGGGAVLGVGTDVLGSIRMPCSFCGICGLKPSGNRLSSLGFSTPVSGMKSAVMMPGPM 290

  Fly   272 SRSARDLLPMMQVLVEPSLKAKLKLDQKV-----------DLKRLRYFYVSSNGMAQCNP----I 321
            :|....|...|:.::...:   .:||..|           ..|.|...:..::|.....|    .
Frog   291 ARDVDSLALFMKAVLCDDM---FQLDPTVPPVPFRDEIYNSSKPLTIGFYDTDGYFLPTPGMKRA 352

  Fly   322 NRETE----------------RVMYKIR----KHFEAVSGK---DVRHADLPYTKLTGKMWRYWM 363
            .:||:                |:.|.:.    :.|.|..|.   :..:||:....|..:|..|
Frog   353 IQETKALLEEAGHKLVPFSPPRIEYALNELCIRGFFADGGSTLVEKFNADIVDPNLKQQMLLY-- 415

  Fly   364 TQEPANFNLLLGNGAELNPFVELFKKILGQSDYSMAAIYGLIDSVLPK-----EKEKLMREATA- 422
             :.|.                 |.|||:   .:.|..|:..|.:.:..     ..::|.:..||
Frog   416 -KVPT-----------------LVKKII---SFFMRPIFPRIANHVDAHCGVGSVKQLWKHNTAI 459

  Fly   423 ---KC------KKSVQDLLGDDGVLFFHSSPRTAP-FHY-YPLVKFNDFAYFSLFNVLHLPATQV 476
               :|      ||     |..|.:|    .|...| |:. .|...|..|.:..|||:|:.||..:
Frog   460 KEYRCEYINEWKK-----LNLDALL----CPMLGPAFNIGCPGKLFAGFCFTMLFNILNFPAGVL 515

  Fly   477 P----------------------------MGL-DSKGMPLGIQVVANPNNDRLCLAVAEELERTF 512
            |                            ||: |..|:||.:|.||.|..:..||.:.:|:|...
Frog   516 PVTTVTPEDEEELKHYKGYYNDLWDKEVIMGMQDGAGLPLAVQCVALPWQEEQCLRLMKEVENVT 580

  Fly   513 GG 514
            .|
Frog   581 RG 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5112	NP_651400.1	PRK07488	52..513	CDD:236030	133/544 (24%)
CG5112	NP_651400.1	Amidase	69..502	CDD:302749	127/516 (25%)
faah.1	XP_012817045.1	Amidase	103..570	CDD:366635	127/512 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303593at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010