DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5112 and faah.3

DIOPT Version :9

Sequence 1:	NP_651400.1	Gene:	CG5112 / 43083	FlyBaseID:	FBgn0039341	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	XP_012817414.2	Gene:	faah.3 / 100145539	XenbaseID:	XB-GENE-997956	Length:	588	Species:	Xenopus tropicalis

Alignment Length:	549	Identity:	142/549 - (25%)
Similarity:	222/549 - (40%)	Gaps:	122/549 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PSLEQQTTITKSAVELAQQIRERRQRSYDIVKAYCERIESVNRDLNAVVDGPFPEALDQAREIDR 105
            |.::.:..::.|..||.:::|:.......::..|.::...|.||.|.:.  .|      ..:.:.
Frog    72 PGVDSRRILSMSLQELTEKLRDGSLSPESVLYPYVKKALEVTRDTNCIT--VF------MNDCET 128

  Fly   106 KLDE-KEYSDEDLRRLPFLGVPFSTKDSTAVAGRLHTLGLLARKSERSTTDAECVRLMKESGAII 169
            :|.| |:...:.|    ..|||.|.|:.....|...|.||:....|....|:..|:::|:.||||
Frog   129 QLQEVKKQKQKGL----LYGVPVSIKEHVGYQGHPSTCGLVQYLDELEEEDSVIVKVLKKQGAII 189

  Fly   170 IATSNVPEVNKWIESRNMLIGCTNNPYDLRRSVGGSSGGEAALIAACCTGFGLGTDIGGSIRIPA 234
            .|.:|||:.....|:.|.:.|.|.||::..:...||||||.|||....:..|.|||||||||:|:
Frog   190 FAKTNVPQTLICYETSNPIYGLTTNPHNHTKGAAGSSGGEGALIGGGGSILGFGTDIGGSIRLPS 254

  Fly   235 FNCGIFGHKPTSGAVNMAGCTFRTGKEKDTMVCAGPMSRSARDLLPMMQVLVEPSLKAKLKLDQK 299
            ..|||.|.|||...:::.|...........::|.|||:|....|:..|:.|:...:   .|||.:
Frog   255 SFCGIAGLKPTPNRLSLHGVRPCVDGMLAVLLCIGPMARDVDSLVLCMKALLCDEM---FKLDPR 316

  Fly   300 V-----------DLKRLRYFYVSSNGMAQCNPINRETERVMYKIRKHFEAVSGKDVRHADLPYTK 353
            |           ..:.||..|..::|....||..|   ||..:.:|..|     :..|..:|:..
Frog   317 VPPLPFNEEVYSTSQPLRIGYYETDGYTLPNPAMR---RVFLETKKLLE-----EAGHMLIPFKP 373

  Fly   354 LTGKMWRYWMTQEPANFNLLLGNGAEL------NPFVE--------------LFKKILGQSDYSM 398
            ...:    :|..| .....|.|:|.:.      |..|:              :.||||.
Frog   374 PRTE----YMLNE-LYMKSLFGDGGQTLSEKFKNNIVDQRLRDLCLLCNLPKIVKKILA------ 427

  Fly   399 AAIYGLIDSVLPKEKEKLMREATAKCKK-------SVQDL----------LGDDGVLFFHSSPRT 446
                .::..:.|:....|.....|.|.|       :|::.          |..|.||    :|..
Frog   428 ----FILKPLRPRYALSLSSAQGASCVKDHWKQNTAVEEYQTEFIAEWRKLNLDVVL----APML 484

  Fly   447 APFHY--YPLVKFNDFAYFSLFNVLHLPATQVPMG--------------------LD-------- 481
            .|...  ||....:..:|..|:|::..||..||:|                    ||
Frog   485 GPAFNPGYPAKLLSAASYTMLYNLVGFPAGVVPVGSVTQTDEEELKNYKGHFNDQLDKLFVKAVE 549

  Fly   482 -SKGMPLGIQVVANPNNDRLCLAVAEELE 509
             ..|:||.:|..|.|..|.|||.:.:|:|
Frog   550 GGLGLPLSVQCAALPYQDELCLRLMKEVE 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5112	NP_651400.1	PRK07488	52..513	CDD:236030	141/538 (26%)
CG5112	NP_651400.1	Amidase	69..502	CDD:302749	133/512 (26%)
faah.3	XP_012817414.2	Amidase	99..571	CDD:418511	133/513 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303593at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010