Protein Alignment XNP and Smarca5

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_444354.2
• Gene: Smarca5 / 93762
• MGIID: 1935129
• Length: 1051
• Species: Mus musculus
• Alignment Length: 965
• Identity: 220/965 - (22%)
• Similarity: 361/965 - (37%)
• Gaps: 282/965 - (29%)

  Fly   233 SSRAESPPRPKRCVVRLKRVSLPKTKPAQKPKKMSSDSEEAATTSKKSRQRRSKSESEADSDYEA 297
            ||..|.||.|               .|...|.|.|:.....:::..|.......:.:...:....
Mouse     2 SSAVEPPPPP---------------PPESAPSKPSAAGAGGSSSGNKGGPEGGAAPAAPCAAGSG 51

  Fly   298 PA-AEEEEEEERKSSGDEEEAANSSDSEVMPQRKRRRKKSESDKGSSDFEPEEKQ---------- 351
            || .|.||..:..|.|.::        |:........:|.::|: ::.||...||
Mouse    52 PADTEMEEVFDHGSPGKQK--------EIQEPDPTYEEKMQTDR-ANRFEYLLKQTELFAHFIQP 107

  Fly   352 -----------KKKGRKRIKKTSSGESDGDGDDDKQKNKRKHIRKIIKTKDLDLTTKEAAKEEDD 405
                       .|.||.|:||           |:||        .::...  |...:...:|||:
Mouse   108 AAQKTPTSPLKMKPGRPRVKK-----------DEKQ--------NLLSVG--DYRHRRTEQEEDE 151

  Fly   406 RRKRIEDRQKLYNRIFVKSESVEINELVLDFDEESKKALLQVDKGLLKKLKPHQVAGVKFMWDAC 470
            .               :.:||.:...:...|::...    .|..|   ||:.:||.|:.::
Mouse   152 E---------------LLTESSKATNVCTRFEDSPS----YVKWG---KLRDYQVRGLNWL---- 190

  Fly   471 FETLKESQEKPGSGCILAHCMGLGKTLQVVTLSHTLLVNTRRTGVDRVLIISPLSTVNNWAREFT 535
             .:|.|:    |...|||..||||||||.::|...:.......|...||:  |.||::||..||.
Mouse   191 -ISLYEN----GINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLV--PKSTLHNWMSEFK 248

  Fly   536 SWMKFANRNDIEVYDISRYKDKPTR------IFKLNEWFNEGGVCILGYDMYRILANEKAKGLRK 594
            .|:.       .:..:....||..|      :....||    .||:..|:|   |..||:...:.
Mouse   249 KWVP-------TLRSVCLIGDKEQRAAFVRDVLLPGEW----DVCVTSYEM---LIKEKSVFKKF 299

  Fly   595 KQREQLMQALVDPGPDLVVCDEGHLLKNEKTSISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQ 659
            ..|             .:|.||.|.:||||:.:|:.|...:|..|::||||||||||.|.:.::.
Mouse   300 NWR-------------YLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLN 351

  Fly   660 FVKPNLLGTYKEYMNRFVNPITNGQYTDSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLP 724
            |:.|::..:..::.:.|        .|::...|.:|::.    ||.:|...:.||..:.:...||
Mouse   352 FLLPDVFNSADDFDSWF--------DTNNCLGDQKLVER----LHMVLRPFLLRRIKADVEKSLP 404

  Fly   725 PKHEYVVYTTLSELQQKLYGYYMTTHREQSGGDVVGKGA-----RLFQDFQDLRRIWTHPMNLRV 784
            ||.|..:|..||::|::.|     |.......|::....     ||......||:...||...
Mouse   405 PKKEVKIYVGLSKMQREWY-----TRILMKDIDILNSAGKMDKMRLLNILMQLRKCCNHPYLF-- 462

  Fly   785 NSDNVIAKRLLSNDDSDMEGFICDETDEDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRN 849
                                                                             
Mouse   463 ----------------------------------------------------------------- 462

  Fly   850 GNAGGGDSDSDLEMLGGLGGGSSVQKDDPSEWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIG 914
                                       |.:|...|:..:..|  |.:|.|:::|.:||.:.:..|
Mouse   463 ---------------------------DGAEPGPPYTTDMHL--VTNSGKMVVLDKLLPKLKEQG 498

  Fly   915 DKLLVFSQSLQSLDVIEHFLSLVDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMC 979
            .::|:|||..:.||::|.:..     .:|||                 |.||||....::|:...
Mouse   499 SRVLIFSQMTRVLDILEDYCM-----WRNYE-----------------YCRLDGQTPHDERQDSI 541

  Fly   980 KQFNNITNLRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYR 1044
            ..:|. .|....:|::|||||||||||..|:.|:::|..|||..|.|::.|.:|.||.|...::|
Mouse   542 NAYNE-PNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFR 605

  Fly  1045 LIAMGTMEQKVYERQVAKQATAKRVIDE-QQISRHYNQTDLMELYSYELKPST----EREMPILP 1104
            .|...|:|:::.||...|......||.: :.:.::.|:....|:.......:|    .:|..|..
Mouse   606 FITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFASKESEITD 670

  Fly  1105 KDRLFAEILTEHEKLIFKYHEHDSLLEQEEHENLTEEERKSAWAEYEAEKTRTVQ 1159
            :|  ...||....|...:.:|..|.:.:....|.|.:...|.: .:|.|..|..|
Mouse   671 ED--IDGILERGAKKTAEMNEKLSKMGESSLRNFTMDTESSVY-NFEGEDYREKQ 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	45/248 (18%)
		HepA	<382..1071	CDD:440319	167/699 (24%)
		DEXHc_ATRX	455..699	CDD:350826	72/249 (29%)
Smarca5	NP_444354.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		19/101 (19%)
		PLN03142	68..1011	CDD:215601	202/884 (23%)
		DEAH box	307..310		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1014..1051