Protein Alignment XNP and SWR1

DIOPT Version :9

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_010621.1
• Gene: SWR1 / 851934
• SGDID: S000002742
• Length: 1514
• Species: Saccharomyces cerevisiae
• Alignment Length: 1480
• Identity: 323/1480 - (21%)
• Similarity: 546/1480 - (36%)
• Gaps: 445/1480 - (30%)

  Fly    19 TDDSNSSSV----------SRRESATESKSASESESSP-PR----SNTKQSRTHKNVKASGKATV 68
            :|.||..|:          .:||:|...|..||.:.:| |.    :..:.....|..:.|...|:
Yeast   136 SDHSNRKSIVPQKRPIQHLKKREAAKSLKFKSERKENPLPLHEHIAEERYDHIAKVEEPSEAFTI 200

  Fly    69 SSSSD-----------SDQAVANSSANDEE---------KEPVCKIRIVPLEKLLASPKTKERP- 112
            ...||           ||.....:|:.:|:         |:|..|:.:.|.::.:.:|....:|
Yeast   201 KCPSDDSSFENTSEHYSDNFYFTTSSEEEDIKKKRGRKKKKPRIKLVVHPPKQTITNPLHVVKPG 265

  Fly   113 ---------SRGSQQKNVTI---NDSSDEEPLKGSKLVLPARKSRNKNASIIELSDSEEVDEEEE 165
                     |..|.:.::|:   |...||:     :.:|...|...:|.::       :.|:|.:
Yeast   266 YESLHEYIASFKSLEDDLTLEEYNKYIDEQ-----RRLLSRLKKGIENGAL-------KYDKETD 318

  Fly   166 SLLVAIPLPKEAQQT----KPEKNS----------------------SKASKESIEKRQKAQKEA 204
            ||.   |:..:..:|    ||:..|                      ||..:.|.:.|....|:.
Yeast   319 SLQ---PITSKEIKTIITYKPDPISYFYKQQDLQIHTDHLINQGIHMSKLFRSSTKARIARAKKV 380

  Fly   205 TTSSARAIRSVNGTRRGSLSSERSSRASSSRAESPPRPKRC--------VVR------LKRVS-- 253
            :....:..:.|.|........|...:.|.:|.......||.        ::|      |||:.
Yeast   381 SQMIEQHFKHVAGAEERKAKEEERHKKSLARFAVQAVKKRWNMAEKAYRILRKDEEEQLKRIEGK 445

  Fly   254 ------LPK-TKPAQKPKKMSSDSEEAATTSKKSRQRRSKSESEADSDYEAPAAEEEEEEERKSS 311
                  |.| |:..:......:|...::|.|..|..  ..|||:.|.|.|...:.:|:||.....
Yeast   446 QHLSKMLEKSTQLLEAQLNQVNDDGRSSTPSSDSND--VLSESDDDMDDELSTSSDEDEEVDADV 508

  Fly   312 GDEEEAAN----------------------SSDSEVMPQRKRRRK-----KSESDKGSSDF---- 345
            |.|...|:                      :..|.|...|.:..|     |.||....|..
Yeast   509 GLENSPASTEATPTDESLNLIQLKEKYGHFNGSSTVYDSRNKDEKFPTLDKHESSSSESSVMTGE 573

  Fly   346 -------EPEEKQKKKGRKRIKKTSS----------GESDGDGD-DDKQKNKRKHIRKIIKTKDL 392
                   ...|.|.:..|:...||.|          .|||||.| ||.:
Yeast   574 ESSIYSSSENESQNENDRESDDKTPSVGLSALFGKGEESDGDLDLDDSE---------------- 622

  Fly   393 DLTTKEAAKEEDDRRK-RIEDRQKLYNRI--FVKSESVEINELVLDFDEES-----KKALLQVD- 448
            |.|...::.|.::..| ::::....:.|.  ||.::: |..:.:.|.:|::     ::.|..||
Yeast   623 DFTVNSSSVEGEELEKDQVDNSAATFERAGDFVHTQN-ENRDDIKDVEEDAETKVQEEQLSVVDV 686

  Fly   449 --KGLLK-KLKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQVVTLSHTLLVNT 510
              ..||: .|:.:|..|:.::         .|.....:..|||..||||||:|.::|...|....
Yeast   687 PVPSLLRGNLRTYQKQGLNWL---------ASLYNNHTNGILADEMGLGKTIQTISLLAYLACEK 742

  Fly   511 RRTGVDRVLIISPLSTVNNWAREFTSWMKFANRNDIEVYDISRYKDKPTRIFKLNEWFNEGG--V 573
            ...|..  ||:.|.|.:.||..||   .:||....:..|    |.....|..|...|.....  |
Yeast   743 ENWGPH--LIVVPTSVLLNWEMEF---KRFAPGFKVLTY----YGSPQQRKEKRKGWNKPDAFHV 798

  Fly   574 CILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDLVVCDEGHLLKNEKTSISKAVTRMRTKR 638
            ||:.|.:  ::.::.:   .|::|.|.|           |.||.|.:||.:::..:|:....|:|
Yeast   799 CIVSYQL--VVQDQHS---FKRKRWQYM-----------VLDEAHNIKNFRSTRWQALLNFNTQR 847

  Fly   639 RIVLTGTPLQNNLREYYCMIQFVKPNL------------LGTYKEYMNRFVNPI--TNGQYTDST 689
            |::||||||||||.|.:.::.|:.|..            |..::::..|.|:.|  |...:....
Yeast   848 RLLLTGTPLQNNLAELWSLLYFLMPQTVIDGKKVSGFADLDAFQQWFGRPVDKIIETGQNFGQDK 912

  Fly   690 ERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLYGYYMTTHREQS 754
            |....:.|     ||::|...:.||..:.:...:|.|:|::||..||:.|:.||..:|:  |.|:
Yeast   913 ETKKTVAK-----LHQVLRPYLLRRLKADVEKQMPAKYEHIVYCKLSKRQRFLYDDFMS--RAQT 970

  Fly   755 GGDVV-GKGARLFQDFQDLRRIWTHPMNLRVN-------------SDNVIAKRLL---------- 795
            ...:. |....:......||::..||....|.             ||....:|.|
Yeast   971 KATLASGNFMSIVNCLMQLRKVCNHPNLFEVRPILTSFVLEHCVASDYKDVERTLLKLFKKNNQV 1035

  Fly   796 ------------SNDDSDMEGFICDE------------------------TDEDEAAS--NSSDS 822
                        :.:|.|:..:..:|                        .:|...||  |..|:
Yeast  1036 NRVDLDFLNLVFTLNDKDLTSYHAEEISKLTCVKNFVEEVNKLRETNKQLQEEFGEASFLNFQDA 1100

  Fly   823 CETFK--------SDASMSGLAASSGKV-----------------KKRKTRNGNAGGGDSD---- 858
            .:.||        ....|........|:                 |.|:.:...:...|::
Yeast  1101 NQYFKYSNKQKLEGTVDMLNFLKMVNKLRCDRRPIFGKNLIDLLTKDRRVKYDKSSIIDNELIKP 1165

  Fly   859 ------------------------SDLEMLG-GLGGGSSVQKDDPSEWWKPFVEERELNNVHHS- 897
                                    .|:..|. ||...|||.::..   .|......|::|..|.
Yeast  1166 LQTRVLDNRKIIDTFAVLTPSAVSLDMRKLALGLNDDSSVGENTR---LKVMQNCFEVSNPLHQL 1227

  Fly   898 ------------------PKLLILLRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSLVDSNTKNY 944
                              .||..|..||||.:..|.:.|:|:|..:.|||:|.||        ||
Yeast  1228 QTKLTIAFPDKSLLQYDCGKLQKLAILLQQLKDNGHRALIFTQMTKVLDVLEQFL--------NY 1284

  Fly   945 EFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAGGLGINLVAA 1009
            .              |..|.||||:..:|.|:.:.::||  |:.|..:|::|:|:|||||||..|
Yeast  1285 H--------------GYLYMRLDGATKIEDRQILTERFN--TDSRITVFILSSRSGGLGINLTGA 1333

  Fly  1010 NRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKRVIDEQQ 1074
            :.|:.:|..|||:.|.|...|.:|.||.:..:|||.::..|:|.     .:.|:|..||.:|...
Yeast  1334 DTVIFYDSDWNPAMDKQCQDRCHRIGQTRDVHIYRFVSEHTIES-----NILKKANQKRQLDNVV 1393

  Fly  1075 ISR------HYNQTDLMELYSYEL-KPSTEREMPILPKDRLFAEILTEHEKLIFKYHEHDSL--- 1129
            |..      ::::..:.:|...|| :.::..:.|::....:.|:...:.|:|:.:..:.|.:
Yeast  1394 IQEGDFTTDYFSKLSVRDLLGSELPENASGGDKPLIADADVAAKDPRQLERLLAQAEDEDDVKAA 1458

  Fly  1130 --------LEQEEHENLT-------EEERKSAWAEYEAEKTRTVQASQYM 1164
                    ::.::.:..|       |||..:...|||.    |....:||
Yeast  1459 NLAMREVEIDNDDFDESTEKKAANEEEENHAELDEYEG----TAHVDEYM 1504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	DTHCT	258..335	CDD:285332	20/103 (19%)
		SNF2_N	458..779	CDD:278600	90/337 (27%)
		DEXDc	483..646	CDD:238005	49/164 (30%)
		Helicase_C	913..1035	CDD:278689	44/121 (36%)
SWR1	NP_010621.1	HSA	340..>393	CDD:413434	7/52 (13%)
		HepA	<659..1413	CDD:223627	196/827 (24%)
		DEXQc_SRCAP	696..932	CDD:350761	73/274 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910