Protein Alignment XNP and Ttf2

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: XP_036019252.1
• Gene: Ttf2 / 74044
• MGIID: 1921294
• Length: 1155
• Species: Mus musculus
• Alignment Length: 1211
• Identity: 256/1211 - (21%)
• Similarity: 429/1211 - (35%)
• Gaps: 358/1211 - (29%)

  Fly    16 PLTTDDSNSSSVSRRESATESKSASESESSPPRSNTKQ-SRTHKNVKASGKATVSSSSDSDQAVA 79
            |....:.|..::.|::...|.:..:..:..  |.|.:| ....|..|....:.:.....||....
Mouse   126 PFRVLNKNQKTLERKQFVEEGERKTADKKL--RENNEQLLDQRKEQKPKSNSRMEKDPSSDLVAT 188

  Fly    80 NSSANDEEKEPVCKIRIVPLEKLLASPKTKERPSRGSQQKNVTINDSSDEEPLKGSKLVLPARKS 144
            ..|..|.|::          ||....||||:.....|:|        ...|.|:|    :|....
Mouse   189 RQSGGDREEQ----------EKSKFQPKTKKAEGMASKQ--------GHGEVLQG----IPKGPH 231

  Fly   145 RNKNASIIELSDSEEVDEEEESLLV-AIPLPKEAQQTKPEKNSSKASKESIEKRQKAQKEATTSS 208
            .:::.|....:..|.:.|:|..||| ::|      ...||   ||..||....|:.. |.....|
Mouse   232 MSESESRGVPNKPETLREKETQLLVPSVP------GQNPE---SKVQKEGHVSREPL-KNGEAPS 286

  Fly   209 ARAIRSVNGTRRGSLSSERSSRASSSRAESPPRPKRCVVRLKRVSLPKTKPAQKPKKMSSDSEEA 273
            |:..:  .|..:|.|  :..|:......|:|..|:.|           :..|......|.|||:.
Mouse   287 AQVTQ--RGLAQGPL--QGPSKTWRPVPEAPAAPELC-----------SGMAHHATSSSEDSEDD 336

  Fly   274 ATTSK-----------KSRQRRSKSESEADSDYEAPAAEEEEEEERKSSGDEEEAANSSDSEVMP 327
            ..:|:           .|:::.|...|:.....:.|||....::     ||..:.|        .
Mouse   337 GVSSRPGSPLLFDSTVDSQKKGSLQHSDQSVQRQMPAASGVSKK-----GDSSDPA--------A 388

  Fly   328 QRKRRRKKSESDKGSSDFEPEEKQKKKGRKRIKKTSSGE--------SDGDGDDDK---QKNKRK 381
            ||.....:.:..||:......:....||.|.:|:..:.|        |...|..:|   |:.::.
Mouse   389 QRANLTTQLKQKKGTLAAVNIQALPDKGEKLLKQIQALEDALSALALSPEQGTKEKCSAQEPEQS 453

  Fly   382 HIRK-------IIKTKDL---------DLTTKEAAKEEDDRRKRIE------------------- 411
            :|.|       ::..:.|         .|..|...:|..:...:..
Mouse   454 NITKAAAAPLHLVPPQPLPRPLIQPASSLGLKAGRQETPEGASQCSGEGWPGTCCMDQVGLQALG 518

  Fly   412 --DRQKLYNRIFVKSESV-EINELVLDFDEESKKALLQVDKGLLKKLKPHQVAGVKF-MWDACFE 472
              ::..|||...:.||:: |::..:.....|:  |:.:...||...|..||...:.: :|
Mouse   519 HMNQHHLYNVWKITSEAIDELHRSLKSCPGET--AVAEDPAGLKVPLLLHQKQALAWLLW----- 576

  Fly   473 TLKESQEKPGSGCILAHCMGLGKTLQVVTLSHTLLVNTRRTGVDR-------------------V 518
              :||| ||..| |||..|||||||.::.|..|.....:....:|                   .
Mouse   577 --RESQ-KPQGG-ILADDMGLGKTLTMIALILTKKNQQKSKEKERSEPVTWLSKNDSSVFTSSGT 637

  Fly   519 LIISPLSTVNNWAREFTSWMKFANRNDIEVYDISRYKDKPTRIFKLNEWFNEGGVCILGYDM--- 580
            ||:.|.|.:::|..|..   |....|.:.:|    ....|.|        :.....:..||:
Mouse   638 LIVCPASLIHHWKNEVE---KRVTSNRLRIY----LYHGPNR--------SRHAKVLSTYDIVIT 687

  Fly   581 -YRILANEKAKGLRKKQREQLMQALVDPGPDL----------------VVCDEGHLLKNEKTSIS 628
             |.:||.|..   ..||..::      ||.:|                ::.||.|.:||.:...|
Mouse   688 TYSLLAKEIP---TTKQEGEV------PGANLSVEGTSAPLLQVVWARIILDEAHNVKNPRVQTS 743

  Fly   629 KAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFVNPITNG---------- 683
            .||.:::.:.|..:||||:||||.:.|.:::|::.:....:..:.::..|....|
Mouse   744 IAVCKLQAQARWAVTGTPIQNNLLDMYSLMKFLRCSPFDEFSLWKSQVDNGSMKGGERLSILTKS 808

  Fly   684 -------QYTDSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQK 741
                   ...|||.:.|..:..|...||:|.....:|..|.:.               |:..:..
Mouse   809 LLLRRTKDQLDSTGKPLVALPARRCQLHRLKLSEDERAVYDIF---------------LARSRSA 858

  Fly   742 LYGYYMTTHREQSGGDVVGKG-----ARLFQDF----------QDLRRIWTHPMNLRVNSDNV-- 789
            |..|   ..|::..|...|:.     :|:.|:|          .|.:|    |..:.|.|..:
Mouse   859 LQSY---LKRQEGRGSHHGRSPDNPFSRVAQEFGSSVSQGCPAADSQR----PSTVHVLSQLLRL 916

  Fly   790 --------IAKRLLSNDDSDMEGFICDETDEDEAASNSSDSCETFKSDASMSGLAASSGKVKKRK 846
                    :.|..|...:.:.||.:                   ...:..:|.|..
Mouse   917 RQCCCHLSLLKSALDPTELESEGLV-------------------LSLEEQLSALTL--------- 953

  Fly   847 TRNGNAGGGDSDSDLEMLGGLGGGSSVQKDDPSEWWKPFVE------EREL-NNVHHSPKLLILL 904
                                    |.|...:||    |.|.      :.|| ::...|.|   :.
Mouse   954 ------------------------SKVDVSEPS----PTVSLNGTCFKAELFDDTRRSTK---VS 987

  Fly   905 RLLQQCEAI-----GDKLLVFSQSLQSLDVIEHFLSLVDSNTKNYEFEGDVGDFKGCWTSGKDYF 964
            .||.:.|||     ..|.::.||....|.|:...|.      ||                ...|.
Mouse   988 SLLAELEAIQKGPGSQKSVIVSQWTSMLQVVALHLK------KN----------------RLTYA 1030

  Fly   965 RLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDTQSIF 1029
            .:|||.:.:||..:.:.||:  :...::.|||..|||:|:||...|.:.:.|:.||||.:.|:..
Mouse  1031 TIDGSVNPKQRMDLVEAFNH--SQGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACD 1093

  Fly  1030 RVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKRVI 1070
            |:||.||.|...|:|.:..||:|:|:.:.|..|:..||:|:
Mouse  1094 RIYRVGQKKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	64/346 (18%)
		HepA	<382..1071	CDD:440319	176/821 (21%)
		DEXHc_ATRX	455..699	CDD:350826	70/300 (23%)
Ttf2	XP_036019252.1	zf-GRF	4..44	CDD:480736
		HepA	<550..1135	CDD:440319	163/725 (22%)
		DEXHc_TTF2	563..813	CDD:350830	66/282 (23%)