Protein Alignment XNP and smarca2

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: XP_031746549.1
• Gene: smarca2 / 734002
• XenbaseID: XB-GENE-1013843
• Length: 1606
• Species: Xenopus tropicalis
• Alignment Length: 1228
• Identity: 284/1228 - (23%)
• Similarity: 446/1228 - (36%)
• Gaps: 392/1228 - (31%)

  Fly    44 SSPPRSNTKQSRTHKNVKASGKATVSSSSDSDQAVANSSANDEEKEPVCKIRIVPLEKLLASPKT 108
            |.||...|             ||||...:   ..:.|......::...|..|...||..|.|...
 Frog   384 SLPPDLRT-------------KATVELKA---LRLLNFQRQLRQEVVACMRRDTTLETALNSKAY 432

  Fly   109 KERPSRGSQQKNVTINDSSDEEPLKGSKLVLPARKSRNKNASIIELSDSEEVDEEEESLLVAIPL 173
            |       :.|..|:.::...|.|:..:.:...||.|.|:            .|...|:|
 Frog   433 K-------RSKRQTLREARMTEKLEKQQKIEQERKRRQKH------------QEYLNSIL----- 473

  Fly   174 PKEAQQTKPEKNSSKASKESIEKRQKAQKEATTSSARAIRSVNGTRRGSLSSERSSRASSSRAES 238
                |..|..|...::....|:|..||   ..|..|              ::||..:..:.|.|.
 Frog   474 ----QHAKDFKEYHRSVTGKIQKLSKA---VATWHA--------------NTEREQKKETERIEK 517

  Fly   239 PPRPKRCVVRLKRVSLPKTKPAQKPKKMSSDSEEAATTSKKSRQRRSKSESEADSDY-------- 295
            .        |::|:             |:.|.|.......:.:.||.....:...:|
 Frog   518 E--------RMRRL-------------MAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTSLV 561

  Fly   296 ----EAPAAEEEEEEERKSSGDE----------------EEAANSSDSEV------------MPQ 328
                :|.||:|::::::|...:|                :|::..||..|            .|:
 Frog   562 WEHKKAQAAKEKKKKKKKKKAEENAEGVGSGLGMDGELIDESSQMSDLPVKVIHTETGKVLLAPE 626

  Fly   329 RKRRRK---------------KSESDKGSSDFEPEEKQKKKGR------KRIKKTSSGESDGDGD 372
            ..:..:               :|:|:..||::|.||.:::..|      ||:         |...
 Frog   627 APKASQLETWLEMNPGYEVAPRSDSEGSSSEYEEEEDEEESSRLDTEEKKRL---------GLNT 682

  Fly   373 DDKQKNKRKHIRKIIKTKDLDLTTKEAAKEEDDRRKRIEDRQKLYNRIFVKSESVEINELVLDFD 437
            :|..|:..|.|.:..| :|:|   .|.:.:||.|:.     |..|......:|.||
 Frog   683 EDNVKHDAKQIIETAK-QDVD---DEYSMQEDARQS-----QSYYGVAHAVTERVE--------- 729

  Fly   438 EESKKALLQVDKGLLKKLKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQVVTL 502
               |::.|.::    ..||.:|:.|:::|.......|..         |||..||||||:|.:.|
 Frog   730 ---KQSSLLIN----GSLKHYQIQGLEWMVSLFNNNLNG---------ILADEMGLGKTIQTIAL 778

  Fly   503 SHTLLVNTRRTGVDRVLIISPLSTVNNWAREFTSW----MKFANRNDIEVYDISRYKDKPTRIFK 563
            ...|:.:.|..|  ..|||.||||::||..||..|    :|.|            ||..|.....
 Frog   779 ITYLMEHKRLNG--PYLIIVPLSTLSNWLYEFDKWAPSVVKIA------------YKGTPAMRRS 829

  Fly   564 LNEWFNEG--GVCILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDLVVCDEGHLLKNEKTS 626
            |......|  .|.:..|: |.|    |.|.:..|.|.:.|           :.||||.:||....
 Frog   830 LVPQLRTGKFNVLLTTYE-YII----KDKHILAKIRWKYM-----------IVDEGHRMKNHHCK 878

  Fly   627 ISKAV-TRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLL---GTYKEYMNRFVNPIT-NGQYT 686
            :::.: |.....|||:||||||||.|.|.:.::.|:.|.:.   .|::::.|.   |.. .|:..
 Frog   879 LTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNA---PFAMTGERV 940

  Fly   687 DSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLY------GY 745
            |..|.:..|:..|   |||:|...:.||....:...||.|.|||:...:|.||:.||      |.
 Frog   941 DLNEEETILIIRR---LHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGI 1002

  Fly   746 YMTTHREQSGGDVVGKGA--RLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGFICD 808
            .:|...|:   |..|||.  .|......||:|..||                         ||..
 Frog  1003 LLTDGSEK---DKKGKGGAKTLMNTIMQLRKICNHP-------------------------FIFQ 1039

  Fly   809 ETDEDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSDLEMLGGLGGGSSV 873
            ..:|..|                 ..|..|:|.:      ||        .||....|
 Frog  1040 HIEESFA-----------------EHLGYSNGII------NG--------PDLYRTSG------- 1066

  Fly   874 QKDDPSEWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSLVD 938
                                     |..:|.|:|.:..|...::|:|.|....:.::|.:.:.
 Frog  1067 -------------------------KFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAF-- 1104

  Fly   939 SNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAGGLG 1003
               :|:.                 |.||||:...|.|.::.|:||. ......:||:||||||||
 Frog  1105 ---RNFL-----------------YLRLDGTTKSEDRASLLKRFNE-EGSPFFIFLLSTRAGGLG 1148

  Fly  1004 INLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKR 1068
            :||.||:.|||||..|||..|.|:..|.:|.||.....:.||..:.::|:|:......|....::
 Frog  1149 LNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1213

  Fly  1069 VID----EQQISRHYNQTDLMELYSYELKPSTER---------------EMPILPKDRLFAEILT 1114
            ||.    :|:.|.|..:..|..:..:|.:..:::               |...:|.|....:::.
 Frog  1214 VIQAGMFDQKSSSHERRAFLQAILEHEEQNESQKKDDLSGDISQEGASQEEDEVPDDETLNQMIA 1278

  Fly  1115 EHEKLIFKYHEHDSLLEQEEHEN------LTEEERKSAW------------AEYEAEK 1154
            .||:....:...|....:|:..|      |.||:...:|            .|.|.||
 Frog  1279 RHEEEFELFMRMDLDRRREDARNPNRKPRLMEEDDLPSWIIKDDAEVERLTCEEEEEK 1336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	63/347 (18%)
		HepA	<382..1071	CDD:440319	189/707 (27%)
		DEXHc_ATRX	455..699	CDD:350826	77/254 (30%)
smarca2	XP_031746549.1	Atrophin-1	31..>467	CDD:460830	24/117 (21%)
		QLQ	175..209	CDD:462622
		HSA	453..525	CDD:214727	22/130 (17%)
		BRK	605..648	CDD:462196	4/42 (10%)
		PLN03142	697..>1218	CDD:215601	189/704 (27%)
		DEXHc_SMARCA2	717..967	CDD:350821	90/310 (29%)
		SnAC	1293..1360	CDD:464219	10/44 (23%)
		Bromo_SNF2L2	1416..1522	CDD:99947