Protein Alignment XNP and rad54l2

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_001076824.1
• Gene: rad54l2 / 733747
• XenbaseID: XB-GENE-5829376
• Length: 1396
• Species: Xenopus tropicalis
• Alignment Length: 1081
• Identity: 344/1081 - (31%)
• Similarity: 527/1081 - (48%)
• Gaps: 249/1081 - (23%)

  Fly   253 SLPKTKPAQKPKKMSSDSEEAATTSKKSRQRRSKSESEADSDYEAPAAEEEEEEERKSSGDEEEA 317
            |:..::|...|:.|..:.|:                 :.|.|.|    |||||:|..:.||:|:
 Frog     5 SISGSEPELDPEDMEEEEED-----------------DEDDDEE----EEEEEDEEDNDGDDED- 47

  Fly   318 ANSSDSEVMPQRKRRRKKSESDKGSSDFEPEEKQKKKGRKRIKKTSSGESDGDGDDDKQK----- 377
                         .::..:|..:.::..|...:|.::|.||  .|:||:|..:.|:.|:|
 Frog    48 -------------DKQDINEKSQNAALGEDSPEQGEEGWKR--STTSGQSGQESDEAKKKRLQKP 97

  Fly   378 -NKRKHIRKIIKTKDLDLTTKEAAKEEDDRRKRIEDRQKLY---------NRIFVKSE----SVE 428
             |.|::|||:::...|:..||.|.:||.:||||:|.::|.|         :..|::.|    :.:
 Frog    98 ANLRRNIRKLLREDQLESVTKTAQQEELERRKRLEQQRKDYPLPLTLPPVSLDFLQEEIELRAAD 162

  Fly   429 INELV-------LD-----FDEESK---------------------------------------- 441
            :::||       ||     .|:|.|
 Frog   163 VSQLVKSQEIICLDSSSGESDDEGKVKSHSIKDEIIELSSGEEDNLQISDNADSTNEVDGDITTE 227

  Fly   442 -------KALLQVD---------------------KGLLKKLKPHQVAGVKFMWDACFETLKESQ 478
                   .||.|.|                     ..|.:.:|.||:.|::|::|...|:|:...
 Frog   228 NSGSHVNDALNQADHLGRVLVNINHPPNEKDIFLAPQLARAVKSHQIGGIRFLYDNLVESLERFS 292

  Fly   479 EKPGSGCILAHCMGLGKTLQVVTLSHTLLVNTRRTGVDRVLIISPLSTVNNWAREFTSWM----- 538
            ...|.||||||.|||||||||::....|.   :.|....||.|.|::|:.||..||..|:
 Frog   293 GSSGFGCILAHSMGLGKTLQVISFLDVLF---QHTSAKTVLAIVPVNTLQNWLAEFNMWLPPPES 354

  Fly   539 ---------------KFANRNDIEVYDISRYKDKPTRIFKLNEWFNEGGVCILGYDMYRILA--- 585
                           |....||       .:|....|...:|:|..:|||.::||:|||:|:
 Frog   355 LPKDHNQELVQPRAFKVHTMND-------EHKTTAARAKVVNDWATDGGVLLMGYEMYRLLSLKK 412

  Fly   586 ---------NEKAKG-----LRKKQREQLM-----QALVDPGPDLVVCDEGHLLKNEKTSISKAV 631
                     ::||.|     |.::.|:|.|     :||..||||:|:|||||.:||...|.|:|:
 Frog   413 SFTAGRKKKSKKAAGPVIIDLDEEDRQQEMLKGIEKALSRPGPDVVICDEGHRIKNCHASTSQAL 477

  Fly   632 TRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFVNPITNGQYTDSTERDLRLM 696
            ..:|::||:||||.||||||.||:||:.||:|:.|||.:|:.|.|..||.|||..|||.:|.|||
 Frog   478 KNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCVDSTPQDKRLM 542

  Fly   697 KHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLYGYYMTTHREQSGGDVVGK 761
            ::|||:||.||||.:|||.::||...||.|.|:|:...||::|:.||..:|...|:  .|:....
 Frog   543 RYRSHVLHSLLEGFVQRRGHTVLKAQLPFKEEHVILVRLSKIQRDLYTEFMNRFRD--AGNSGWL 605

  Fly   762 GARLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGFICDETDEDEAASNSSDSCETF 826
            |....:.|....:||.||        :|:.:.|...:       :.:|.|.|.....:::.|.
 Frog   606 GLNPLKAFCVCCKIWNHP--------DVLYEALQKEN-------LANEQDLDVEDLGTNNRCN-- 653

  Fly   827 KSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSDLEMLGGLGGGSSVQKDD---PSEWWKPFVEE 888
                      |.|||:|......|...|  ..:..:.|.|:....|.:|.:   ..||.|..:.:
 Frog   654 ----------AQSGKIKVEPNSLGALMG--ETAHTKQLQGIVLNPSHEKANQVVTYEWAKEILSD 706

  Fly   889 RELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSLVDSNTKNYEFEGDVGDF 953
            .....:.:|||:::|..|:::...:|||:|||||||.:|.::|.||    :..|.....|..|..
 Frog   707 YIPGQLQNSPKMVLLFHLIEESMRMGDKILVFSQSLSTLSIMEEFL----AKRKMPIPAGSDGQE 767

  Fly   954 KGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAGGLGINLVAANRVVIFDVS 1018
            ...|....:|:|||||.|..:||.:..|||:.:|.:..|||:|||||.||:||:.|||||:||.|
 Frog   768 GHTWIRNVNYYRLDGSTSASERERLINQFNDPSNEKVWLFLLSTRAGCLGVNLIGANRVVVFDAS 832

  Fly  1019 WNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKRVIDEQQISRHYNQTD 1083
            |||.||.|::.||||:||.||||||||::..|:|:|:|:||:.||..:.||:|:.....::.:.:
 Frog   833 WNPCHDAQAVCRVYRYGQRKPCYIYRLVSDFTLEKKIYDRQITKQGMSDRVVDDLNPEVNFTRRE 897

  Fly  1084 LMELYSY-ELKPSTERE--------MPILPKDRL-FAEILTEHEKLIFKYHEHDSLLEQEEHENL 1138
            :..|..: |.:|...|:        ..:|.|..| :..::|:..      .:|:|||...:.:.|
 Frog   898 VENLLHFVEEEPDASRQHLDSSSFHEAVLQKACLQYPHLITKEP------FQHESLLLDRKEQKL 956

  Fly  1139 TEEERKSAWAEYEAEK------TRTVQASQYMSYDRNAFGN 1173
            |..|:|:|...||.||      ||......|.:.|.| .||
 Frog   957 TLAEKKAAKRGYEEEKRASVPYTRPSYTQYYPAPDHN-LGN 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	64/305 (21%)
		HepA	<382..1071	CDD:440319	283/826 (34%)
		DEXHc_ATRX	455..699	CDD:350826	114/285 (40%)
rad54l2	NP_001076824.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..103		32/134 (24%)
		DEXHc_ARIP4	269..545	CDD:350827	114/285 (40%)
		HepA	<272..885	CDD:440319	252/657 (38%)
		DEAH box	461..464		2/2 (100%)
		LXXLL motif 1	549..553		2/3 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1117..1168
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1194..1250
		LXXLL motif 2	1273..1277
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1340..1396