Protein Alignment XNP and Rad54b

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_001034645.1
• Gene: Rad54b / 623474
• MGIID: 3605986
• Length: 886
• Species: Mus musculus
• Alignment Length: 1033
• Identity: 251/1033 - (24%)
• Similarity: 406/1033 - (39%)
• Gaps: 328/1033 - (31%)

  Fly   298 PAAEEEEEEERKSSGDEEEAAN--SSDSEV-MPQRKRRRKKSESD-----KGSSDFEPEEKQKKK 354
            |......:|..:|...||||::  ...|.| ....|::.||.|.|     :|.|....:.:.|..
Mouse    81 PPVHSASKEITESKAQEEEASSLLKYFSVVWCKASKKKHKKWEGDAILIVRGRSFTLKDLEGKDI 145

  Fly   355 GR------KRIKKTSSGESDGDG-----------DDDKQKNK-------------RKHIRKIIKT 389
            ||      |.::....|::...|           .||....|             .:..||....
Mouse   146 GRGIGYKFKDLENVEEGQTLIIGGKEIEILGTISSDDFNSGKCFQHGSGSPAVPSSQAARKCFSN 210

  Fly   390 --KDLDLTTKEAAKEEDDRRKR--------------IEDRQKLYNRIFVKSESVEINELVLDFDE 438
              |.:..:|:...|..:|.|.|              .|:.|:::||     ....|.::|
Mouse   211 PFKSVCQSTQAQGKRWNDCRPRHNPCTPNALVMPRPDENHQRMFNR-----HCSPIVDVV----- 265

  Fly   439 ESKKALLQVDKGLLKKLKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQVVTLS 503
                    :|..|:..|:|||..|:.|::: |...::...:   .|.|||..||||||||.::|.
Mouse   266 --------IDPHLVHHLRPHQKDGIIFLYE-CVMGMRAVGK---CGAILADEMGLGKTLQCISLI 318

  Fly   504 HTLLVNTRRTG---VDRVLIISPLSTVNNWAREFTSWMKFANRNDIEVYDISRYKDKPTRIFKLN 565
            .||.......|   :.:.||::|.|.||||.:||..|:   ....|:::.:.  :|.....| :|
Mouse   319 WTLQCQGPYGGKPVIKKTLIVTPGSLVNNWRKEFQKWL---GSERIKIFTVD--QDHKVEEF-IN 377

  Fly   566 EWFNEGGVCILGYDMYRILANEKAKGLRKKQREQLMQAL--VDPGP-DLVVCDEGHLLKNEKTSI 627
            ..|:  .|.|:.|:|                   |:::|  :...| .|::|||||.|||.....
Mouse   378 STFH--SVLIISYEM-------------------LLRSLDQIKTIPFGLLICDEGHRLKNSSIKT 421

  Fly   628 SKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFVNPITNGQYTDSTERD 692
            :.|::.:..::.::|||||:||:|:|::.::.||.|.:||:...|...:..||...:...|::.:
Mouse   422 TTALSSLSCEKTVILTGTPVQNDLQEFFALVDFVNPGILGSLSSYRKIYEEPIIISREPSSSKEE 486

  Fly   693 LRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLYGYYMTTHREQS--- 754
            ..|.:.|:..|.:|....|.||...|:..|||||.|.||:.....||.:||...:   |.||
Mouse   487 RELGERRATELTRLTGRFILRRTQEVINKYLPPKIENVVFCRPGALQIELYRKLL---RSQSVRF 548

  Fly   755 --------GGDVVGKGARLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGFICDETD 811
                    ...::..||        |:::..||..|   ..:|..|...|:         |:|.:
Mouse   549 CLQGLLENSAHLICIGA--------LKKLCNHPCLL---FSSVKGKEFSSS---------CEENE 593

  Fly   812 EDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSDLEMLGGL-----GGGS 871
            |                                   ||             :..||     .|.:
Mouse   594 E-----------------------------------RN-------------LCQGLLSVFPAGYN 610

  Fly   872 SVQKDDPSEWWKPFVEERELNNVHHSPKLLILLRLLQQCEAI--GDKLLVFSQSLQSLDVIEHFL 934
            .:|          |.||       .|.||.:|::||.....:  .:|:::.|...|:|:|:|..
Mouse   611 PLQ----------FSEE-------ESGKLQVLVKLLAVIHELRPTEKVILVSNYRQTLNVLEEV- 657

  Fly   935 SLVDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNN--ITNLRARLFLIST 997
                                 |...|....||||...|.||:.:...||:  .|:.   :||:|:
Mouse   658 ---------------------CKRHGYACARLDGQTPVSQRQHIVDSFNSKYSTDF---IFLLSS 698

  Fly   998 RAGGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAK 1062
            :|||:|:||:..:.::::|:.|||:.|.|::.||:|.||..|.:||||:..||:|:|:|:||::|
Mouse   699 KAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQISK 763

  Fly  1063 QATAKRVIDEQQISRHYNQTDLMELYSYELKPSTEREMPILPKDRLFAEILTEHEKLIFKYHE-- 1125
            |..:..|:|..:.|.|                               .:...|..|.:|..||
Mouse   764 QGLSGAVVDLTRSSEH-------------------------------IQFSVEELKNLFTLHESS 797

  Fly  1126 ----HDSLLEQEEHENLTEEERKSAWAEYEAEKTRTVQASQYMSYDRNAFGNQVMGQFGNASGSV 1186
                || ||:                .|...||..|..||:                     |.|
Mouse   798 HCVTHD-LLD----------------CECTGEKGHTEDASE---------------------GPV 824

  Fly  1187 TSNKI-FGFRSDILLQLLNMK-------ISKDHQELNQ---NQVIQLVPTYLQQLYNE 1233
            .|.:. ||.:....|:.|:|.       .|.||..|..   .::.:.|..:.|.:.|:
Mouse   825 ASRQCQFGPQKSDALRPLSMSQLKQWKHFSGDHLNLPDPFLERIRENVSFFFQNITNQ 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	44/215 (20%)
		HepA	<382..1071	CDD:440319	193/730 (26%)
		DEXHc_ATRX	455..699	CDD:350826	75/249 (30%)
Rad54b	NP_001034645.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95		3/13 (23%)
		HepA	<274..772	CDD:440319	177/641 (28%)
		DEXHc_RAD54B	274..508	CDD:350824	79/264 (30%)
		DEGH box	409..412		2/2 (100%)