Protein Alignment XNP and smarcad1a

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_001018610.2
• Gene: smarcad1a / 557875
• ZFINID: ZDB-GENE-050522-499
• Length: 972
• Species: Danio rerio
• Alignment Length: 1124
• Identity: 249/1124 - (22%)
• Similarity: 420/1124 - (37%)
• Gaps: 308/1124 - (27%)

  Fly    20 DDSNSSSVSRRESATESKSASESESSPPRSNTKQSRTHKNVKASGKATVSSSSDSDQAVANSSAN 84
            |.|||..        |:|.|.:.::.....:.|.||......:|....|....||...:......
Zfish    25 DGSNSDK--------ENKQAHQRKADGQFPSGKTSRQVLEDVSSDDEVVRMGKDSASDLQQHINK 81

  Fly    85 DEEKEPVCKIRIVP------LEKLLASPKT------------KERPSRGSQQKNVTINDSSDEEP 131
            |.|.:.:..:.|.|      |.:::.:..|            .:..|.|.:.|....:|  |::|
Zfish    82 DMEDKIIKLLEIFPQKSKKDLLEVIENTSTLDGAVAHCLMIYGDEDSGGRKDKGGRSDD--DDQP 144

  Fly   132 LKGSKLVLPARKSRNKNASIIELSDSEEVDEEEESLLVAIPLPKEAQQTKPEKNSSKASKESIEK 196
            .|       .||.:..::|..|..|||:.:.||.|......|.|:.::..|:  ..|.....|.|
Zfish   145 KK-------KRKIQRSDSSESEDEDSEDEESEEPSREKQEALLKKLKRKLPD--IEKEVLRDILK 200

  Fly   197 RQKAQKEATTSSARAIRSVNGTRRGSLSSERSSRASSSRAESPPRPKRCVVRLKRVSLPKTKPAQ 261
            ......|....|.....|.:.:......|::.|::|.|:.::                  .|..|
Zfish   201 EHDWDYENALGSLLVFSSTDTSSPEDQKSKQKSKSSHSKEKT------------------DKITQ 247

  Fly   262 KPKKMSSDSE----------EAATTSKKSRQRRSKSESEA-DSDYEAPAAEEEEEEERKSSGDEE 315
            :|...||.|.          |.::.|....|:.:.|:|.: :|.::....:|....:..:|.||:
Zfish   248 RPSGSSSLSRWLTAASSHVPEVSSMSALKTQKSALSKSTSKNSSFKRKRGDEMPLNDVSASEDED 312

  Fly   316 EAANSSDSEVMPQRKRRRKKSESDKGSSDFEPEEKQKKKGR---KRIKKTSSGESDG----DGDD 373
            |.    ||:|             |..|.|.:.|::....|.   |.|:.......|.    .|..
Zfish   313 EI----DSDV-------------DSMSDDQDSEDEDSISGTLQDKIIQFLQDASLDELALISGCS 360

  Fly   374 DKQKNKRKHIRKIIKTKDLDLTTKEAAKEEDDRRKRIEDRQKLYNRIFVKSESVEIN-------- 430
            .|:..|...:|.....||:        ||:                 |.|...:.|:
Zfish   361 IKKAQKIISLRPFNTWKDV--------KEQ-----------------FFKDNGLSIDLVHGCKVV 400

  Fly   431 ----ELVLDFDEESKK----------ALLQVDKGLLK---------KLKPHQVAGVKFMWDACFE 472
                ::|||.....:|          .:::...|.:|         ||:.:|:.|:|::
Zfish   401 LKERQVVLDLMGRCEKIAQKMTKDVTQVIEAGMGSIKQPKVLNSNLKLQAYQLIGLKWL------ 459

  Fly   473 TLKESQEKPGSGCILAHCMGLGKTLQVVTLSHTLLVNTRRTGVDRV-LIISPLSTVNNWAREFTS 536
            .|....:..|   |||..||||||:|.:    ..|.:....|:... ||..|.||::||.||...
Zfish   460 ILLHQHKLSG---ILADEMGLGKTIQAI----AFLAHLYEKGIKGPHLITVPSSTLDNWVRELGL 517

  Fly   537 WMKFANRNDIEVY----DISRY--KDKPTRIFKLNEWFNEGGVCILGYDMYRILANEKAKGLRKK 595
            |.....   :.:|    :..:|  :|..|.:...|       :.:..|::  .:.|:..:.|.:|
Zfish   518 WCPSLK---VLIYYGSVEDRKYLRQDILTGLIDFN-------IIVSTYNL--TIGNDHDRSLFRK 570

  Fly   596 QREQLMQALVDPGPDLVVCDEGHLLKNEKTSISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQF 660
            .:.:           ..|.||||:|||..:...:.:..:..:.|::||||||||||.|...::.|
Zfish   571 LKLK-----------YAVFDEGHMLKNMNSLRYRHLMTINAEHRLLLTGTPLQNNLLELMSLLNF 624

  Fly   661 VKPNLLGTYKEYMNRFVNPITNGQYTDSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPP 725
            :.|::..:....:::..:       |.|:|.:....|.|......:::..|.||..|.:...|||
Zfish   625 IMPSMFSSSTSQISKMFS-------TRSSEEESSFHKDRIAQARLIMKPFILRRVKSEVLKELPP 682

  Fly   726 KHEYVVYTTLSELQQKLYGYYMTTHREQSGGDVVGKGARLFQDFQDLRRIWTHPMNLRVNSDNVI 790
            |.|.:....:|:.|.|||.......::...||    ...|......||::..||:..|
Zfish   683 KMEKIEMCPMSDAQHKLYDILFKRLKKTPNGD----KRELCNVMMQLRKMANHPLLHR------- 736

  Fly   791 AKRLLSNDDSDMEGFICDETDEDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGG 855
                                             :.:.||.    |||.|..:.|..|..
Zfish   737 ---------------------------------QYYTSDK----LAAMSKAMLKEPTHY------ 758

  Fly   856 DSDSDLEMLGGLGGGSSVQKDDPSEWWKPFVEERELNN-----------------VHHSPKLLIL 903
            |:|..|           :|:|      ...:.:.||:|                 :..|.|..:|
Zfish   759 DADPAL-----------IQED------MEVMSDFELHNLCREYSSISGFQLEKALILDSGKFALL 806

  Fly   904 LRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSLVDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDG 968
            .:.|.:.:..||::::|||....||::|..|..:|                      ..|.||||
Zfish   807 TKTLAKLKEKGDRVVLFSQFTMMLDIVEILLKHLD----------------------HQYVRLDG 849

  Fly   969 SCSVEQREAMCKQFNNITNLRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYR 1033
            |..:.:|..:..::|  ||....:||:||||||.||||.:||.|::.|:..||.:|.|:..|.:|
Zfish   850 STPMAERIGLIDKYN--TNPEIFVFLLSTRAGGQGINLASANTVILHDIDCNPFNDKQAEDRCHR 912

  Fly  1034 FGQIKPCYIYRLIAMGTME 1052
            .||.:...:.:||:..::|
Zfish   913 MGQTRTVQVIKLISKDSIE 931

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	60/335 (18%)
		HepA	<382..1071	CDD:440319	168/726 (23%)
		DEXHc_ATRX	455..699	CDD:350826	63/250 (25%)
smarcad1a	NP_001018610.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..76		14/58 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..177		17/60 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..333		29/150 (19%)
		ComEA	<348..>381	CDD:441164	7/40 (18%)
		HepA	<439..944	CDD:440319	154/631 (24%)
		DEGH box	579..582		2/2 (100%)