Protein Alignment XNP and ercc6l2

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_001314698.2
• Gene: ercc6l2 / 553504
• ZFINID: ZDB-GENE-110411-274
• Length: 1269
• Species: Danio rerio
• Alignment Length: 693
• Identity: 189/693 - (27%)
• Similarity: 295/693 - (42%)
• Gaps: 195/693 - (28%)

  Fly   455 LKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQVVTLSHTLLVNTRRTGV---- 515
            |:.:|..|:||:    ::...:|:     ||||...||||||:||:.....:|   ::||.
Zfish    60 LRDYQREGIKFI----YQNYAKSR-----GCILGDDMGLGKTVQVIGFLAAVL---QKTGTWKDV 112

  Fly   516 --------------DRV----LIISPLSTVNNWAREFTSWMKF------ANRNDIEVYDISRYKD 556
                          :||    :|::|||.:.||..|..:|..|      ..|.|.|:..:.|
Zfish   113 ENNRPQFLLSQKPSERVQKVFVIVAPLSVLYNWKDELDTWGHFRVVVVHGVRKDEELARVQR--- 174

  Fly   557 KPTRIFKLNEWFNEGGVCILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDLVVCDEGHLLK 621
                           |.|.:....:..|.      |...|...:..|       .|:.||.|.:|
Zfish   175 ---------------GRCEIALTTFETLR------LCLDQFNSINWA-------AVIVDEAHKIK 211

  Fly   622 NEKTSISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFVNPITNGQYT 686
            |.|:.|::|:.:||.|.||.||||.|||||.|.:|::.:..|..||:...:.|||.:||..||..
Zfish   212 NHKSKITQAMKQMRCKVRIGLTGTILQNNLEELWCVMNWAVPRCLGSLGAFKNRFSDPIEKGQKH 276

  Fly   687 DSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLYGYYMTTHR 751
            ..|:|.|...:.....|.|.|.....||..|:::..||.|.:.|||.:|::.|:.:|
Zfish   277 TVTKRALAEGRKAVQELAKKLSRWFLRRTKSLISDQLPKKDDRVVYCSLTDFQRTVY-------- 333

  Fly   752 EQSGGDVVGKGARLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGFICDETDEDEAA 816
                                                    :.:|.:||..:             .
Zfish   334 ----------------------------------------RAVLDSDDVTL-------------M 345

  Fly   817 SNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSD----SDLEMLGGLGGGSSV--QK 875
            ..||..|            ..|||:.:|:.....||.|....    |.|.:|..:....::  .|
Zfish   346 LQSSGKC------------PCSSGRPRKKCCYKLNADGVPVRHLYFSYLAILRKVANHVALLQSK 398

  Fly   876 DDPSEWWKPFV--------------EER-------ELNNVHHSPKLLILLRLLQQCEAIGDKLLV 919
            |..|:..:.:|              .||       .:::..:|.|:.::.:||....|..||:|:
Zfish   399 DGTSKKQEKYVTTICEQVFRKFPDFTERCKQAAFEAMSDPMYSGKMKVMQKLLNHFIAKKDKVLL 463

  Fly   920 FSQSLQSLDVIEHFLSLVDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNN 984
            ||.|.:.|||:|.:                      |...|.:|.||||:...:.|..:.|:||:
Zfish   464 FSLSTKLLDVLESY----------------------CMAEGLEYHRLDGNTKSKDRVKIVKEFNS 506

  Fly   985 ITNLRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMG 1049
            ..::  .|.|:||.|||||:|.:.||.||:||.:|||::|.|:|.||||.||.:...::|||::|
Zfish   507 SRDV--NLCLVSTLAGGLGLNFIGANVVVLFDPTWNPANDLQAIDRVYRIGQCRDVTVFRLISLG 569

  Fly  1050 TMEQKVYERQVAKQATAKRVIDEQQISRHYNQTDLMELYSYEL 1092
            |:|:.:|.|||.||.....||.::...|::......:.|:.||
Zfish   570 TVEEIIYLRQVYKQQLQSSVIGQENARRYFEAVQGTDGYAGEL 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	1/4 (25%)
		HepA	<382..1071	CDD:440319	184/670 (27%)
		DEXHc_ATRX	455..699	CDD:350826	80/271 (30%)
ercc6l2	NP_001314698.2	None