|
Fly 22 SNSSSVSRRESATESKSASESESSPPRSNTKQSRTHKNVKASGK---ATVSSSS-----DSDQAV 78
|.|||....||:.::|...:..||..::...:.:...:::.|.| |.::||| |.||..
Human 1151 SGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNS 1215
Fly 79 ANSSANDEEK-EPVCKIRIVPLEKLLASPKTKERPSRG----SQQKNVTINDSSDE---EPLKGS 135
....::||:| :|| .|.|:.|..|....|.| |:...||::|..|: |.....
Human 1216 IGEGSSDEQKIKPV-------TENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1273
Fly 136 KLVLPARKSRNKNASIIELSDSEEVDEEEESLLVAIPLPKEAQQTKPEKNSSKASKESIEKRQKA 200
|::|...|: .||..|:...::| ||:. :||...
Human 1274 KMLLEEIKA--------NLSSDEDGSSDDE----------------PEEG---------KKRTGK 1305
Fly 201 QKEATTSSARAIRSVNGTRRGSLSSERSSRASSSRAESPPRPKRCVVRLKRVSLPKTKPAQKPKK 265
|.|.......|...|| |...|.|.....||.:..::|.| :::...:..::.|.
Human 1306 QNEENPGDEEAKNQVN-----------SESDSDSEESKKPRYRHRLLRHK-LTVSDGESGEEKKT 1358
Fly 266 MSSDSEEAATTSKKSRQRRS-KSESEADSDYEAPAAEEE----EEEERKSSGDEEEAANSSDSEV 325
...:.:|. |.|.||. .||...|||::.....|| |:|:|..:...::|....:...
Human 1359 KPKEHKEV-----KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRS 1418
Fly 326 MPQRKRRRK------KSESDKGSSDFEPEEKQKKKGRKRIKKTSSGESDGDGDDDKQKNK-RKHI 383
..|:|:||: .|..:|.:|:.|.|||::::.. ::....|.:.:.||.|...| ||.|
Human 1419 YKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEE---EEEEEEEEEDENDDSKSPGKGRKKI 1480
Fly 384 RKIIKTKDLDLTTKEAAKEEDDRRKRIEDRQKLYNRIFVKSESVEINE-----------LVLDFD 437
|||:|...|...|:.|.|||::|||||.:|::...:: .|.:||.: ||||.|
Human 1481 RKILKDDKLRTETQNALKEEEERRKRIAEREREREKL---REVIEIEDASPTKCPITTKLVLDED 1542
Fly 438 EESKKALLQVDKGLLKKLKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQVVTL 502
||:|:.|:||.:.::.|||||||.||:||||.|.|::|::::.||||||||||||||||||||:.
Human 1543 EETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSF 1607
Fly 503 SHTLLVNTRRTGVDRVLIISPLSTVNNWAREFTSWMK-FANRNDIEVYDISRYKDKPTRIFKLNE 566
.||:|: ..:......|::.||:|..||..||..|.: ..:...:||.:::..|....|.:.|..
Human 1608 LHTVLL-CDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQR 1671
Fly 567 WFNEGGVCILGYDMYRILA---NEKAKGLRKKQREQLMQALVDPGPDLVVCDEGHLLKNEKTSIS 628
|..:|||.|:||:|||.|| |.|: :|.:|...:||||||||.|||||||:||||.:::|
Human 1672 WQEDGGVMIIGYEMYRNLAQGRNVKS----RKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVS 1732
Fly 629 KAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFVNPITNGQYTDSTERDL 693
||:..:|::|||:||||||||||.||:||:.|:|.||||:.||:.|||:|||.|||..|||..|:
Human 1733 KAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDV 1797
Fly 694 RLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLYGYYMTTHREQSGGDV 758
|:||.|:|||:::|.||:||:||:.|..:||||||||:...::.:|.|||.||: .|....|.:.
Human 1798 RVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYL-DHLTGVGNNS 1861
Fly 759 VG----KGARLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGFICDETDEDEAASNS 819
.| .||:||||||.|.||||||..|:: |.:..:.....|:..|:.||..::||...:.:|
Human 1862 EGGRGKAGAKLFQDFQMLSRIWTHPWCLQL--DYISKENKGYFDEDSMDEFIASDSDETSMSLSS 1924
Fly 820 SDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSDLEML---------GGLGG------ 869
.|..:..| |.||.|..:.::|.| ||:|:|:: ||.|.
Human 1925 DDYTKKKK-------------KGKKGKKDSSSSGSG-SDNDVEVIKVWNSRSRGGGEGNVDETGN 1975
Fly 870 ----------GSSVQKDDPS----EWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVF 920
..:....:|| :|:|.||.:.:...:.||.|:::|..:|:..|.||||:|||
Human 1976 NPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF 2040
Fly 921 SQSLQSLDVIEHFLSL-----VDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCK 980
||||.|||:||.||.| .:...|...::|: |.|....||:|||||.:.:.|:...:
Human 2041 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGE-----GKWLRNIDYYRLDGSTTAQSRKKWAE 2100
Fly 981 QFNNITNLRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRL 1045
:||:.||:|.|||:|||:||.|||||||||||:|||.|||||:|.|||||||||||.||.|:||.
Human 2101 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRF 2165
Fly 1046 IAMGTMEQKVYERQVAKQATAKRVIDEQQISRHYNQTDLMELYSYEL----KPSTE----REMPI 1102
:|.||||.|:|:|||.||:.:.||:|:||:.||:...:|.|||::|. .|::| |:.|:
Human 2166 LAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPM 2230
Fly 1103 LPKDRLFAEILTEHEKLIFKYHEHDSLLEQEEHENLTEEERKSAWAEYEAEKTRTV--------- 1158
||||.:.||:|..|::.|..||||||||:.:|.|.|||||||:|||||||||....
Human 2231 LPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGT 2295
Fly 1159 --------QASQYMSYD---RNAFGNQVMGQFGN--------ASGSVTSNKIFGFRSDILLQLL- 1203
..:.|:.:: .:|..||.:....| |:.|||:.:|... .||:..:.
Human 2296 NLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPL-EDIISAVWK 2359
Fly 1204 -NMKISKDH-----------QELN--------------QNQVIQ-----LVPTYLQQLYNEMNNG 1237
||.:|:.. |||: |..:|. |:...|||.||:....
Human 2360 ENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQ 2424
Fly 1238 DPTMYKDLLNLHSNIVHPSGMYMNPLLYANQNPNAAGYNQGTGGVPPMAGGSVAHGPPAAPAP 1300
..|..:..|. |..:..|..:.|||..| |..:..|..| |:||| ...||...||
Human 2425 QMTYQQATLG-HLMMPKPPNLIMNPSNY--QQIDMRGMYQ------PVAGG--MQPPPLQRAP 2476
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