Protein Alignment XNP and smarca2

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: XP_073805988.1
• Gene: smarca2 / 334032
• ZFINID: ZDB-GENE-030131-5964
• Length: 1578
• Species: Danio rerio
• Alignment Length: 1275
• Identity: 281/1275 - (22%)
• Similarity: 471/1275 - (36%)
• Gaps: 380/1275 - (29%)

  Fly    40 SESESSPPRSNTKQSRTHKNVKASGKATVSSSSDSDQAVANSSANDEEKEPVCKIRIVPLEKLLA 104
            :.::||.|:..|:           |:...:||:.....::..|.......|:......|:.....
Zfish   250 THTQSSGPKQWTE-----------GQGAETSSTPQKLLISAPSGRPSPAPPLAPTGTQPVPSTSL 303

  Fly   105 SPKTKERPSRGSQQKNVTINDSSDEEPLKGSKLVLPARKSRNKNASIIELSDSEEVDEEEESLLV 169
            :.:.:.:|..|..|.::.|.....:      ..|.|.:|.:.        .|..|:.:|.|..|.
Zfish   304 TSQPQPQPPAGPGQPSLIIQLQQKQ------NRVTPIQKPQG--------LDPVELLQEREYRLQ 354

  Fly   170 AIPLPKEAQQTKPEKNSSKASKESIEKRQKAQKEATTSSARAIRSVNGTRRGSLSSERSSRASSS 234
            |    :.|.:.:..:|...:....:  |.||     |...:|:|.:|..|:..|......|..::
Zfish   355 A----RIAHRIQELENLPGSLPPDL--RTKA-----TVELKALRLLNFQRQLRLDVVACMRRDTT 408

  Fly   235 -----RAESPPRPKRCVVRLKRVSLPKTKPAQKPKKMSSDSEEAATTSKKSRQRRSKSESEADSD 294
                 .:::..|.||..:|..|:    |:..:|.:|:           ::.|:||.|.:...:|.
Zfish   409 LETALNSKAYKRSKRQTLREARM----TEKLEKQQKI-----------EQERKRRQKHQEYLNSI 458

  Fly   295 YEAPAAEEEEEEERKSSG-------------DEEEAANSSDSEVMPQRKRRRKKSESDKGSSDFE 346
            .:  .|::.:|..|..||             ...|.....::|.:.:.:.||..:|.::|.....
Zfish   459 LQ--HAKDFKEYHRSISGKIQKLSKAIATWHTNTEREQKKETERIEKERMRRLMAEDEEGYRKLI 521

  Fly   347 PEE--------------------------------KQKKKGRKRIKKTSSGESDGDG-------- 371
            .::                                |:|||.||: ||..:|:::|.|
Zfish   522 DQKKDKRLAYLLQQTDEYVANLTELVYEHKAAQAAKEKKKKRKK-KKKEAGDAEGMGAIGPDGEP 585

  Fly   372 -DDDKQKNK------RKHIRKIIKTKDLDLTTKEAA-----------------------KEEDDR 406
             |::.|.::      :....|:::..|...:::..|                       :||||.
Zfish   586 IDENSQMSELPVKVIQTETGKVLQGTDAPKSSQLEAWLEMNPGYEVAPRSDSEESGSDFEEEDDE 650

  Fly   407 R--KRIEDRQKLYNRIFVKSESVEINELVL---------DFDEE--------SKKALLQVDKGLL 452
            .  .|.|..:|.    .:...|.|::|...         |.|:|        |.::...|...::
Zfish   651 EVVSRAESEEKK----VIDPNSDEVSETAAKHIIESAKQDVDDEYSSQAGQTSSQSYYGVAHAVI 711

  Fly   453 KK------------LKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQVVTLSHT 505
            ::            ||.:|:.|:::|.......|..         |||..||||||:|.:.|...
Zfish   712 ERVDKQSTFLINGTLKQYQIQGLEWMVSLYNNNLNG---------ILADEMGLGKTIQTIGLITY 767

  Fly   506 LLVNTRRTGVDRVLIISPLSTVNNWAREFTSW----MKFANRNDIEVYDISRYKDKPTRIFKLNE 566
            |:.:.|..|  ..|||.||||::||..|...|    :|.|            ||..|:....|..
Zfish   768 LMEHKRLNG--PYLIIVPLSTLSNWVYELDKWAPSIVKIA------------YKGTPSMRRSLVP 818

  Fly   567 WFNEG--GVCILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDLVVCDEGHLLKNEKTSISK 629
            ....|  .|.|..|: |.|    |.|.:..|.|.:.|           :.||||.:||....:::
Zfish   819 QLRSGKFNVLITTYE-YII----KDKHILAKIRWKYM-----------IVDEGHRMKNHHCKLTQ 867

  Fly   630 AV-TRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLL---GTYKEYMNRFVNPIT-NGQYTDST 689
            .: |.....||::||||||||.|.|.:.::.|:.|.:.   .|::::.|.   |.. .|:..|..
Zfish   868 VLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNA---PFAMTGERVDLN 929

  Fly   690 ERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLY------GYYMT 748
            |.:..|:..|   |||:|...:.||....:...||.|.|||:...:|.:|:.||      |..:|
Zfish   930 EEETILIIRR---LHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSAIQKVLYRHMQGKGILLT 991

  Fly   749 THREQSGGDVVGKGA--RLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGFICDETD 811
            ...|:   |..|||.  .|......|::|..||...: :.:...|:.|         ||
Zfish   992 DGSEK---DKKGKGGAKTLMNTIMQLKKICNHPYMFQ-HIEESFAEHL---------GF------ 1037

  Fly   812 EDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSDLEMLGGLGGGSSVQKD 876
                                                .||...|    .||....|
Zfish  1038 ------------------------------------PNGIISG----PDLYRASG---------- 1052

  Fly   877 DPSEWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSLVDSNT 941
                                  |..:|.|:|.:.:|...::|:|.|....:.::|.:...
Zfish  1053 ----------------------KFELLDRILPKLKATNHRVLLFCQMTSLMTILEDYFGY----- 1090

  Fly   942 KNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAGGLGINL 1006
            :|:.                 |.||||:...|.|..:.|:||. ...:..:||:||||||||:||
Zfish  1091 RNFL-----------------YLRLDGTTKSEDRAMLLKKFNE-EGSQYFIFLLSTRAGGLGLNL 1137

  Fly  1007 VAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKRVID 1071
            .||:.|||||..|||..|.|:..|.:|.||.....:.||..:.::|:|:......|....::||.
Zfish  1138 QAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ 1202

  Fly  1072 ----EQQISRHYNQTDLMELYSYELKPSTEREMPILPKDRLFAEILTEHEKLIFKYHEHDSLLEQ 1132
                :|:.|.|..:..|..:..:|.:...|.|   :|.|....:::..:|.....:...|....:
Zfish  1203 AGMFDQKSSSHERRAFLQAILEHEEQNMEEDE---VPDDETLNQMIARNEDEFELFMRMDLDRRR 1264

  Fly  1133 EEHEN------LTEEERKSAW------------AEYEAEK 1154
            |:..|      |.||:...:|            .|.|.||
Zfish  1265 EDARNPKRKPRLMEEDELPSWILKDDAEVERLTCEEEEEK 1304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	69/405 (17%)
		HepA	<382..1071	CDD:440319	187/761 (25%)
		DEXHc_ATRX	455..699	CDD:350826	76/254 (30%)
smarca2	XP_073805988.1	None