Protein Alignment XNP and Smarca1

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_001258119.1
• Gene: Smarca1 / 317575
• RGDID: 1561046
• Length: 1062
• Species: Rattus norvegicus
• Alignment Length: 1016
• Identity: 241/1016 - (23%)
• Similarity: 384/1016 - (37%)
• Gaps: 307/1016 - (30%)

  Fly   272 EAATTSKKSRQRRSKSESEADSDYEAPAAEEEEEEERKSSGDEEEAANSSDSEVMPQRKRRRKKS 336
            ||||.              |.||..|.....|:|:...|:..||.||.::........|..:|
  Rat     8 EAATV--------------AASDARATIVVLEDEQPGPSTFKEEGAAAAATEATTATEKGEKK-- 56

  Fly   337 ESDKGSSDFEPEEKQKKKGRKRIKKTSSGESDGDGD-DDKQKN------KRKHIRKIIK------ 388
              :|.:|.|:         .|...|||..|.:.|.: ::|..|      :.|....::|
  Rat    57 --EKITSPFQ---------LKLAAKTSKSEKEMDPEYEEKMVNIPLKADRAKRFEFLLKQTELFA 110

  Fly   389 -----------TKDLDLTTKEAAKEEDDRRKRIEDRQKLYNRIFVKSESVEINELVLDFDEESKK 442
                       |..|::.......::||::..|......:.|    :|..|..||:    .||:|
  Rat   111 HFIQPSAQKSPTSPLNMKLARPRVKKDDKQSLISVGDYRHRR----TEQEEDEELL----SESRK 167

  Fly   443 -----ALLQVDKGLLK--KLKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQVV 500
                 ...:|....:|  .|:.:|:.|:.::     .:|.|:    |...|||..||||||||.:
  Rat   168 TSNVCVRFEVSPSYVKGGPLRDYQIRGLNWL-----ISLYEN----GVNGILADEMGLGKTLQTI 223

  Fly   501 TLSHTLLVNTRRTGVDRVLIISPLSTVNNWAREFTSWMK------FANRNDIEVYDISRYKDKPT 559
            .|...|.......|...||:  |.||::||..||..|:.      |....|:....| |.:..|
  Rat   224 ALLGYLKHYRNFPGPHMVLV--PKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFI-RDEMMP- 284

  Fly   560 RIFKLNEWFNEGGVCILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDLVVCDEGHLLKNEK 624
                 .||    .||:..|:|.     .|.|.:.||...:.:           |.||.|.:||||
  Rat   285 -----GEW----DVCVTSYEMV-----IKEKSVFKKFHWRYL-----------VIDEAHRIKNEK 324

  Fly   625 TSISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFVNPITNGQYTDST 689
            :.:|:.|...::..|::||||||||||.|.:.::.|:.|::..:..::.:.|        .|.:.
  Rat   325 SKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWF--------DTKNC 381

  Fly   690 ERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLYGYYMTTHREQS 754
            ..|.:|::.    ||.:|:..:.||..:.:...||||.|..:|..||::|::.|     |.....
  Rat   382 LGDQKLVER----LHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWY-----TKILMK 437

  Fly   755 GGDVVGKGA-----RLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGFICDETDEDE 814
            ..||:....     ||......||:...||...
  Rat   438 DIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLF-------------------------------- 470

  Fly   815 AASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSDLEMLGGLGGGSSVQKDDPS 879
                                                                          |.:
  Rat   471 --------------------------------------------------------------DGA 473

  Fly   880 EWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSLVDSNTKNY 944
            |...|:..:..:  |.:|.|::.|.:||.:.:..|.::|:|||..:.||::|.:
  Rat   474 EPGPPYTTDEHI--VSNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDY----------- 525

  Fly   945 EFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAGGLGINLVAA 1009
                       |...|.:|.||||....|:||...:.| |..|....:|::|||||||||||.:|
  Rat   526 -----------CMWRGYEYCRLDGQTPHEEREEAIEAF-NAPNSSKFIFMLSTRAGGLGINLASA 578

  Fly  1010 NRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQ---------VAKQAT 1065
            :.|:::|..|||..|.|::.|.:|.||.||..::|||...|:|:::.||.         |.:|.
  Rat   579 DVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQG- 642

  Fly  1066 AKRVIDEQ----------QISRHYNQTDLMELYSYELKPSTEREMPILPKDRLFAEILTEHEKLI 1120
              |:||:|          |:.|| ..|.:......||            .|.....||...||..
  Rat   643 --RLIDQQSNKLAKEEMLQMIRH-GATHVFACKESEL------------TDEDIVTILERGEKKT 692

  Fly  1121 FKYHEHDSLLEQEEHENLTEEERKSAW----AEY-EAEKTRTVQASQYMSYDRNAFGNQVMGQFG 1180
            .:.:|....:.:....|...:..:|.:    .:| |.:|..||:..:....:|.|  |..:..:.
  Rat   693 AEMNERMQKMGESSLRNFRMDLEQSLYKFEGEDYREKQKLGTVEWIEPPKRERKA--NYAVDAYF 755

  Fly  1181 NASGSVTSNKI--------------FGFRSDILLQLLNMKI 1207
            ..:..|:..|:              |.|....|.:||..:|
  Rat   756 REALRVSEPKVPKAPRPPKQPNVQDFQFFPPRLFELLEKEI 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	46/218 (21%)
		HepA	<382..1071	CDD:440319	179/732 (24%)
		DEXHc_ATRX	455..699	CDD:350826	73/249 (29%)
Smarca1	NP_001258119.1	PLN03142	64..1061	CDD:215601	221/942 (23%)