Protein Alignment XNP and Chd6

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: XP_008760567.1
• Gene: Chd6 / 311607
• RGDID: 1310465
• Length: 2711
• Species: Rattus norvegicus
• Alignment Length: 1262
• Identity: 273/1262 - (21%)
• Similarity: 460/1262 - (36%)
• Gaps: 395/1262 - (31%)

  Fly    23 NSSSVSRRESATESKSASESESSPPR-SNTKQSRTHKNVKASGKATVSSSSDSDQAVANSSANDE 86
            |.|.:|......:.||.|..:.||.: .|.:::..|...:.....|                 :|
  Rat    19 NHSPMSDASVNFDYKSPSPFDCSPDQGENIEEAANHCLPQKDFYTT-----------------EE 66

  Fly    87 EKEPVCKIRIVPLEKLLASPKTKERPSRGS-QQKNVTINDSSDEEPLKGSKLVLPARKSRNKNAS 150
            |.:.:..      .||::....::...||: .:|.....:..::|..|.||
  Rat    67 EADTLFS------RKLMSHNGMEDNGGRGTGVKKKRKKKEPGEQEGTKASK-------------- 111

  Fly   151 IIELSDSEEVDEEEESLLVAIPLPKEAQQTKPEKNSSKASKESIEKRQKAQKEAT----TSSARA 211
                      |.|        |.||..::.|..|...:|.:   .||.|..|||.    ....|.
  Rat   112 ----------DRE--------PKPKRKREPKEPKEPRRAKE---PKRAKEPKEAKQKDGVKKPRK 155

  Fly   212 IRSVNGTRRGSLSSERSSRASSSRAESPPRPKRCVVRLKRVSLPKTKPAQKPKKMSSDSEEAATT 276
            .|..:||:.|                   :.||        |.....|..||||.|.|.......
  Rat   156 PREASGTKEG-------------------KEKR--------SCTDCGPRTKPKKASKDQGPTPVE 193

  Fly   277 SKKSRQRRSKSESEA-DSDYEAPAAEEEEEEERKSSGDEEEAANSSDSEVMPQRKRRRKKSESDK 340
            .||..:|::::..|: :.|...|....:..||...|.|.::..:..      |.|||:...:.|.
  Rat   194 RKKKGKRKNETTVESLELDQSLPNPSLQSPEEPSESADSQKRRSGR------QVKRRKYNEDLDF 252

  Fly   341 GSSDFEPEEKQKKKGRKRIKKTSSG----ESDGDGDDDKQKNKRKHIRKIIKTK----------- 390
            ...| :..|.....|..|....|:.    :::...:||     ...|.||:.:|
  Rat   253 KVVD-DDGETIAVLGAGRTSALSASTLAWQAEEPPEDD-----ANIIEKILASKTVQEVHPGEPP 311

  Fly   391 -DLDL----------------TTKEAAKEE--DDRRKRIEDRQKLYNRIFVKSES-------VEI 429
             ||:|                |.:|..|:.  ..:.||..::|.....||.:.:.       :||
  Rat   312 FDLELFYVKYRNFSYLHCKWATMEELEKDPRIAQKIKRFRNKQAQMKHIFTEPDEDLFNPDYIEI 376

  Fly   430 NELV-----------------------LDFDEESKKALLQVDKGLLKKLKPHQ----VAGVKFMW 467
            :.::                       |.::|.:.:....||...:|:.:..|    |..|:...
  Rat   377 DRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPAKVKEFESLQILPEVKPVERPA 441

  Fly   468 DACFETLKESQEKPGS----------------------GCILAHCMGLGKTLQVVTLSHTLLVNT 510
            ...::.|:.|:|...|                      .||||..||||||:|.:.....:.|.
  Rat   442 SDAWQKLETSREYKNSNRLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSIAFLSEIFVR- 505

  Fly   511 RRTGV-DRVLIISPLSTVNNWAREFTSWMKF---------ANRNDIEVYDISRYKDKP----TRI 561
               |: ...|||:||||:.||.|||.:|.:.         .:|..|:.|::. |:|..    :.:
  Rat   506 ---GIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHGSQISRQMIQQYEMV-YRDAQGNPLSGV 566

  Fly   562 FKLNEWFNEGGVCILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDL-------VVCDEGHL 619
            ||.:       |.|..::|  |||:                     .|:|       ||.||.|.
  Rat   567 FKFH-------VVITTFEM--ILAD---------------------CPELKKIHWSCVVIDEAHR 601

  Fly   620 LKNEKTSISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFVNPITNGQ 684
            |||....:.:.:..|..:.:::||||||||::.|.:.::.|::|:...:...::..|      |.
  Rat   602 LKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEF------GD 660

  Fly   685 YTDSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLYGYYMTT 749
            .  .||..::.       |..:|:..:.||....:...|.||.|.::...|:.:|:|.|...:
  Rat   661 L--KTEEQVKK-------LQSILKPMMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAIL-- 714

  Fly   750 HREQSGGDVVGKGA------RLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGFICD 808
               :.....:.|||      .|.....:||:...||..:....:.::
  Rat   715 ---EKNFSFLTKGANQHNMPNLINTMMELRKCCNHPYLINGAEEKIL------------------ 758

  Fly   809 ETDEDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSDLEMLGGLGGGSSV 873
               ||...::||::     ||..:..:..::|
  Rat   759 ---EDFRKAHSSEA-----SDFQLQAMIQAAG--------------------------------- 782

  Fly   874 QKDDPSEWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSLVD 938
                                     ||:::.:||.:..|.|.|:|:|||.::.||::|.:|.
  Rat   783 -------------------------KLVLIDKLLPKLIAGGHKVLIFSQMVRCLDILEDYLI--- 819

  Fly   939 SNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAGGLG 1003
              .:.|.:|                 |:||......|:|...:|....:.|. :||:.|||||||
  Rat   820 --QRRYTYE-----------------RIDGRVRGNLRQAAIDRFCKPDSDRF-VFLLCTRAGGLG 864

  Fly  1004 INLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKR 1068
            |||.||:..:|||..|||.:|.|:..|.:|.||.|...:||||...:.|::::::...|....|.
  Rat   865 INLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKA 929

  Fly  1069 VIDEQQISRHYNQTDLMELYSYELKPSTEREMPILPKDRLFAEILTEHEKLIFKYHEHDSLLEQE 1133
            ::  |.|:|..:...:.:|...|::       .:|.|....|.:..|.|...|...:.|.:|::.
  Rat   930 IL--QDINRKGSTNGVQQLSKMEVE-------DLLRKGAYGALMDEEDEGSKFCEEDIDQILQRR 985

  Fly  1134 EHENLTEEERKS---AWAEYEAEKTRT 1157
            .|....:.|.|.   |.|.:.|...||
  Rat   986 THTITIQSEGKGSTFAKASFVASGNRT 1012

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	71/359 (20%)
		HepA	<382..1071	CDD:440319	179/801 (22%)
		DEXHc_ATRX	455..699	CDD:350826	72/290 (25%)
Chd6	XP_008760567.1	PTZ00449	<100..372	CDD:185628	70/345 (20%)
		CD1_tandem_CHD5-9_like	287..352	CDD:349315	14/69 (20%)
		CD2_tandem_CHD5-9_like	371..429	CDD:349310	7/57 (12%)
		PLN03142	459..>984	CDD:215601	163/695 (23%)
		DEAD-like_helicase_N	460..681	CDD:475120	67/270 (25%)