Protein Alignment XNP and rrp1

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_594246.1
• Gene: rrp1 / 2542440
• PomBaseID: SPAC17A2.12
• Length: 897
• Species: Schizosaccharomyces pombe
• Alignment Length: 1063
• Identity: 243/1063 - (22%)
• Similarity: 388/1063 - (36%)
• Gaps: 309/1063 - (29%)

  Fly   155 SDSEEVDEEEESLLVAIPLPKEAQQTKPEKNSSKASKESIEKRQKAQKEATTSSARAIRSVNGTR 219
            |..:::..:||.          |::.:.|.|||..|........:.|.|.....||
pombe    11 STFQQLQNDEEL----------ARRLQDEWNSSSPSSAPSSSSSQNQVELDEQFAR--------- 56

  Fly   220 RGSLSSERSSRASSSRAESPPRP----------KRCVVRLKRVSLPKTKPAQKPKKMSSDSEEAA 274
              ||.:.:||..|....:.||..          ||.  |.||:...|..|.:.|.:::|
pombe    57 --SLQNSQSSSYSLPPFDHPPSKNPTSSSLSTRKRW--RQKRLWSFKNFPFRPPTRLTS------ 111

  Fly   275 TTSKKSRQRRSKSESEADSDYEAPAAEEEEEEERKSSGDEEEAANSSDSEVMPQRKRRRKKSESD 339
            |.|..|......|.|...|....|                  ...||.|..:|          |.
pombe   112 TPSNSSSLPSIPSSSSTPSISSIP------------------HTTSSVSNDIP----------SV 148

  Fly   340 KGSSDF-----EPEE----------KQKKKGRKRIKKTSSGE------SDGDGDDDKQKNKRKHI 383
            .||||.     .||.          ||..:....:...||..      |.......::|.:.:|:
pombe   149 LGSSDHPIDLDNPEHLTPPSSFITAKQLSRLPTPLPPPSSSSLPTGTISTNSFCPYERKVQPEHV 213

  Fly   384 RKIIKTKDLDLTTKEAAKEEDDRRKRIEDRQKLYNRIFVKSESVEINELVLDFDEESKKALLQVD 448
                 ||:|....:.......|    ..|.|       :|:|.|:                   .
pombe   214 -----TKELHQLLQHNTPSPFD----TIDLQ-------LKNEQVQ-------------------S 243

  Fly   449 KGLLKKLKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQVVTLSHTLLVN---- 509
            .|||..|.||||.|..:|     |::::|.:   .|.::|..||||||:|.:.|   ||..
pombe   244 AGLLVSLLPHQVEGHAWM-----ESMEQSSK---CGGVMADDMGLGKTIQTIAL---LLTQKSQD 297

  Fly   510 -TRRTGVDRVLIISPLSTVNNWAREFTSWMKFANRNDIEVYDISRYKDKPTRIFKLNEWFNEGGV 573
             .|:|.    ||:..::.::.||.|.::.:..:.:..:.::..|..|:..:  ::|::
pombe   298 PLRKTN----LIVVSVALLHQWAEELSTKVHPSKKLSVYIHHGSTKKNLDS--YELSQ------- 349

  Fly   574 CILGYDM----YRILANEKAKGLRKKQREQLMQ---ALVDPGPDL---------VVCDEGHLLKN 622
                ||:    |.:||.|      .||.:....   |...|.|..         :|.||.|.::|
pombe   350 ----YDVVLTTYSMLAYE------MKQNDAFNNNNPATATPPPACSLLETSWYRIVLDEAHTIRN 404

  Fly   623 EKTSISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFVNPITNGQYTD 687
            ..|..:|...::..|.|..|:|||:||::.|:|.:::|::......:..:......|:.:.: .|
pombe   405 RDTLAAKCCVKLDAKYRWCLSGTPIQNHIDEFYSLLKFLRIKPYCVWSLFAKDISRPLKSYR-AD 468

  Fly   688 STERDLRLMKHRSHILHKLLEGCIQRRDYSVLA---PY--LPPKHEYVVYTTLSELQQKLYGYYM 747
            ..|..|:.       |..||...:.||......   |.  ||||....|...|...::.||...|
pombe   469 IVEAALKR-------LRILLASTVFRRTKETRVNNLPIVNLPPKTIRTVSVNLLPEERALYNEQM 526

  Fly   748 TTHRE------QSGGDVVGKGARLFQDFQDLRRIWTHPMNLRVNS-DNVIAKRLLSNDDSDMEGF 805
            ::.:.      .:..|:...|. |......||:...||..::.:| ||....|     ||:....
pombe   527 SSAQSLVDNYFNNDHDLSRYGF-LLVSLLRLRQFCCHPWLVKSSSLDNSFRIR-----DSENVRN 585

  Fly   806 ICDETD----------EDEAASNSSDSCET---------FKSDASMS-------GLAASSGKVKK 844
            .|...|          :|...|...|.|..         |.....||       |.:::|..:.|
pombe   586 ACKSLDPLTIERIATLQDFNCSVCLDPCLAPVFIIPCGHFTCQECMSMLVGQKYGSSSTSTIIAK 650

  Fly   845 RKTRNGNAGGGDSDSDLEMLGGLGG--------------GSSVQKDDPSEW-------------- 881
            .....||. ..||..|..:|..:.|              ..|.|:.....|
pombe   651 CPMCRGNI-VQDSLVDATILQAIHGPLNSLKQLELDMNQSFSEQESIKLRWENRIDQMFTKKFGK 714

  Fly   882 ----WKPFVEERELNNVHHSPKLLILLRLLQQCEAIG----DKLLVFSQSLQSLDVIEHFLSLVD 938
                ||   ...:||....:    ||       :.||    :|:||:||..|.|.::.|.|.|
pombe   715 RASEWK---SSSKLNQARQT----IL-------DIIGSKRNEKILVYSQFSQYLCLVSHMLKL-- 763

  Fly   939 SNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAGGLG 1003
            .|.:                    :.|.||:.|..||:.....|||..::  .:.|:|.:||.:|
pombe   764 ENIR--------------------HVRYDGTMSANQRQKSLHSFNNDKDV--LVMLVSLKAGSVG 806

  Fly  1004 INLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKR 1068
            :||..||.|::.:..:|||.:.|:|.||:|.||.||..:||.|...|:|:::...|..|:...|.
pombe   807 LNLTIANHVILQEPFYNPSIEDQAIDRVHRLGQQKPVTVYRFITKDTIEERIVSVQRKKRQLVKE 871

  Fly  1069 VIDEQQ---ISRHYNQTDLMELY 1088
            .:|..:   :|| .::.:|:.|:
pombe   872 ALDSNENNPLSR-LDKEELLYLF 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	66/317 (21%)
		HepA	<382..1071	CDD:440319	185/783 (24%)
		DEXHc_ATRX	455..699	CDD:350826	64/264 (24%)
rrp1	NP_594246.1	HepA	<244..874	CDD:440319	175/716 (24%)
		RING_Ubox	603..663	CDD:473075	13/60 (22%)