Protein Alignment XNP and rrp2

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_596602.1
• Gene: rrp2 / 2540464
• PomBaseID: SPBC23E6.02
• Length: 1040
• Species: Schizosaccharomyces pombe
• Alignment Length: 1227
• Identity: 258/1227 - (21%)
• Similarity: 428/1227 - (34%)
• Gaps: 362/1227 - (29%)

  Fly     3 KKN-PNARHTDAATPLTTDDSNSSSVSRRESATESKSA------SESESSPPRSNTKQSRTHKNV 60
            |.| |:...:.::..|..:|.|...:.||.:....|.|      .:|.||   .||.:|...|
pombe    30 KNNTPDYSSSASSDQLLKNDINRHEMERRIAFLNRKQALFNAFMHDSSSS---LNTMESNIEK-- 89

  Fly    61 KASGKATVSSSSDSDQAVANSSANDEEKEPVCKIR---IVPLEKLLASPKT-KERPS-------- 113
                   |:....:|.:|.....|:|:......:.   ....:..|.:||. .:||:
pombe    90 -------VNGLFPNDNSVIALKPNEEKLNSSLSVENNDSTYTDATLIAPKIGLDRPNINAITIDV 147

  Fly   114 RGSQQKNVTINDSSDE-EPLKGSKLVLPARKSR--NKNASIIELSDSEEVDEEEESLLVAIPLPK 175
            .|...:| .|:.|:|: .|.:...|....:.|.  |.|| :|.:||||..|..
pombe   148 DGHSLQN-EISSSTDKLSPSQSDALFEQKQDSLFWNDNA-VIVVSDSESDDNN------------ 198

  Fly   176 EAQQTKPEKNSSKASKESIEKRQKAQKEATTSSARAIRSVNGTRRGSLSSERSSRASSSRAESPP 240
              .:||    ||....:.:..::|...|        :..:|..|:              :.|.|.
pombe   199 --VRTK----SSLNDHDKVNMKEKRNLE--------LAFMNSKRK--------------KLELPS 235

  Fly   241 RPKRCVVRLKRVSLPKTKPAQKPKKMSSDSEEAATTSKKSRQRRSKSESEADSDYEAPAAEEEEE 305
            .|.     |.......|.....|.....::.:...|:......:. .:.:..|:.....::||:.
pombe   236 LPV-----LSTAGPSYTNSLALPPFHHHNNYKMFNTTHTLEDDKF-LQGKGTSNNPISLSDEEDN 294

  Fly   306 E---ERKSSGDEEEAANSSDSEVMPQRKRRRKKSESDKGSSDFEPEEKQKKKGRKRIKKTSSGES 367
            |   :.|..|        |||.::|
pombe   295 EINFQNKRYG--------SDSVILP---------------------------------------- 311

  Fly   368 DGDGDDDKQKNKRKHI-------RKIIKTKDLDLTTKEAAKEEDDRRKRIEDRQKLYNRIFVKSE 425
            .|...|.|.....||:       .:....:..:|:.....|.:||:::::|
pombe   312 GGLLHDSKLPEPGKHLFHLQWYHDRFHNIEGFNLSDSNNQKVQDDQQQQLE-------------- 362

  Fly   426 SVEINELVLDFDEE--SKKALLQ-VDKGLLKKLKPHQVAGVKFMWDACFETLKESQEKPGSGCIL 487
                 ||..|.||:  :...:.: ...||:..|..||..|:  ||   .:.|:||.:|.|   ||
pombe   363 -----ELFKDLDEQLVNDPTIREGTPAGLIPTLMEHQKEGL--MW---LKRLEESSKKGG---IL 414

  Fly   488 AHCMGLGKTLQVVTLSHTLLVNTRRTGVDRVLIISPLSTVNNWAREFTSWMKFANRNDIEVYDIS 552
            |..||||||:|.:.|..|....::  .|...|||:|:|.:..|..|..:.:..::|..:.::..|
pombe   415 ADDMGLGKTVQALALLVTRPPESK--SVKTTLIITPVSLLQQWHNEILTKIAPSHRPTVYIHHGS 477

  Fly   553 RYKDKPTRIFKLNEWFNEGGVCILGYDM----YRILANEKAKGLRKKQREQLMQALVDPGP---- 609
            ..|.|...             .::.||:    |.::|.|      .|.:....:::.|..|
pombe   478 SKKHKIAE-------------QLMSYDIVLTTYNVIAYE------FKNKMAYDKSIEDNAPIKKF 523

  Fly   610 ----------DLVVCDEGHLLKNEKTSISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPN 664
                      ..|:.||...:||..|..::....:.:..|..|:|||:||.:.|:|.:|:|::..
pombe   524 EHLPFFEAEWYRVILDEAQTIKNRNTLAARGCCLLESTYRWCLSGTPMQNGVEEFYSLIKFLRIK 588

  Fly   665 LLGTYKEYMNRFVNPITNGQYTDSTERDLRLMKHRSHILHKLLEGCIQRRDYS-------VLAPY 722
            ....:..:...|..|:::...|.:..:..|          .||:..:.||..:       :|.
pombe   589 PYSDWSSFSKDFTIPLSSNINTSAPMKRFR----------GLLKAVLLRRTKNTKIDGKPILT-- 641

  Fly   723 LPPKHEYVVYTTLSELQQKLY-----GYYMTTHREQSGGDVVGKGARLFQDFQDLRRIWTHPMNL 782
            ||||......|.||..:.:.|     |..:...:....|.:......|......||:...||.
pombe   642 LPPKTAVKSETDLSSSEMEFYNTLQSGAQIQMRKYLQEGTITTHYGSLLVLLLRLRQACCHPW-- 704

  Fly   783 RVNSDNVIAKRLLSNDDSD--------------------------------ME------------ 803
                  :|..|..:.||:|                                |:
pombe   705 ------LIVAREAAVDDNDSFQAKNRAIYNQIYPEAVNRLKLIETLQCSLCMDVVAELLIIVPCG 763

  Fly   804 GFICDE-------TDEDEAASNSSDS-------CETFKSDASM---------SGLAASSGKVKKR 845
            .|:|.|       :.||.|...|:::       ||.:.....:         ||:|.......|.
pombe   764 HFLCRECLTHVITSSEDMAKQTSNENISPKCSVCEEYIDTERLLSYALFRRYSGMAPIVDADNKL 828

  Fly   846 KTRNGNAGGGDSDSDL------EMLGGLGGGSSVQKDDPSEWWKPFVEERELNNVHHSPKLLILL 904
            :|.|        .|:|      .:|.....|..: ..||..|......|:.||.|....|
pombe   829 RTEN--------ISELLPKQYSNILENRQMGMKI-FTDPKHWTTSTKIEKALNAVKEIIK----- 879

  Fly   905 RLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSLVDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDGS 969
                  :...||:|:|||          |:|.::..|..:..|            |..|....|.
pombe   880 ------KQPTDKILIFSQ----------FVSFLELFTVPFRQE------------GIKYLMYTGG 916

  Fly   970 CSVEQREAMCKQFNNITNLRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRF 1034
            .|..:|......|....|:  |:.|||.:||.:|:||..||.|:|.|..|||..:.|::.|.:|.
pombe   917 LSTAERNQALINFEVDPNV--RVLLISLKAGNVGLNLTCANHVIILDPFWNPYIEEQAVDRAHRI 979

  Fly  1035 GQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKRVIDE---QQISRHYNQTDLMELY 1088
            ||.||..|.|::...|:|::|...|..|:......:.|   ::||| .|..:|..|:
pombe   980 GQDKPVNILRIVTNNTIEERVLALQDRKRELIDSALGEKGLREISR-LNTKELSFLF 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	44/299 (15%)
		HepA	<382..1071	CDD:440319	178/801 (22%)
		DEXHc_ATRX	455..699	CDD:350826	64/261 (25%)
rrp2	NP_596602.1	HepA	<380..1016	CDD:440319	167/728 (23%)
		RING_Ubox	742..812	CDD:473075	10/69 (14%)