Protein Alignment XNP and pqn-15

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_001367558.1
• Gene: pqn-15 / 180705
• WormBaseID: WBGene00004106
• Length: 2171
• Species: Caenorhabditis elegans
• Alignment Length: 1251
• Identity: 293/1251 - (23%)
• Similarity: 471/1251 - (37%)
• Gaps: 343/1251 - (27%)

  Fly     6 PNARHTDAATPLTTDDSNSSS--VSRRESATESKSA--SESESSPPRSNTK----------QSRT 56
            ||....:.|.|:.....|.:.  ...:...|..|:.  ::.:|.|.::|.|          |..|
 Worm   719 PNGLPPNNAGPMIQQGKNIAGGYPPNQNKVTPGKNVPKNQQQSRPQQANGKVQAKSSPDLSQPST 783

  Fly    57 HKNVKASGKATVSSSSDS--DQAVANSSANDEEKEPVCK-----------------IRIVPLEKL 102
            .|....:.||.::...|:  .....:.....|..|.||:                 .|.:.:.||
 Worm   784 SKQRPPANKADMTVIRDAIVSHVKGSRKMTPEYIEYVCEELNRLMRELEKADMKTDRRYISVRKL 848

  Fly   103 LASPKTKERPSRGSQQKNVTINDSSDEEPLKGSKLVLPARKSRNKNASIIELSDSEEVDEEEES- 166
            ||.          .|::.:||        :...::.:|||....:.:    |.| |.|||..|.
 Worm   849 LAL----------IQEEKLTI--------IIPPRIPMPARYPPTEES----LGD-EPVDETVEDR 890

  Fly   167 ----------LLVAIPL---------------PKEAQQTKPE--KNSSKASKESI-----EKRQK 199
                      |..|.||               .|||...:.:  ||.....||::     |::.|
 Worm   891 AARYDDYMQVLANAYPLNTWDSNFMKIDDDIIRKEALHYRDQDMKNREMYLKENLHTFPEERQTK 955

  Fly   200 AQKEATTSSARAIRSVNGTRRGSLSSERSSRASSSRAESPP-----------------------R 241
            |:.|..           |.......:|...:..::....||                       .
 Worm   956 AKIEYL-----------GLSLLDFQTELRKKVLATTVLVPPNDFLINPWSIRRTKYEYLQELKRH 1009

  Fly   242 PKRCVVRLKR--------VSLPKTKPAQKPKKMSSDSEEAATTSKKSRQRRSKSESEADSDYEAP 298
            |.|.::..:|        .||  ||.|::.|:....:....|..:||.|:...:|::.
 Worm  1010 PDRAILEKRRKVTNFHFLQSL--TKHAREFKEFHKRNMLNHTKVRKSMQQYITNENKR------- 1065

  Fly   299 AAEEEEEEER----KSSGDEEEAANSSDSEVMPQRKRRRKKSESD--KGSSDFEPEEKQKKKGRK 357
            .|.||.:.|:    |...::||...:...|...||.....:...|  |...|...:::....|..
 Worm  1066 IAREEMKNEKNRIQKLIQEDEEGYRAMLDEKKDQRLVYLLEQTDDYIKSLCDLLKQQQNATAGSL 1130

  Fly   358 RIKKTSSGESDGDGDDDKQKNKRKHIRKIIKTKDLDLTTKEAAKEEDDRRKRIEDRQKLYNRIFV 422
            ..|.....|.||..::||.|:            .||....:..:.|:..:..|||       .:.
 Worm  1131 ATKSYIRKEYDGVAEEDKVKS------------ILDKARNDDDEYENKTKMNIED-------YYT 1176

  Fly   423 KSESVEINELVLDFDEESKKALLQVDKGLLK-KLKPHQVAGVKFMWDACFETLKESQEKPGSGCI 486
            .:..|.         ||.|:....:..|... ||||:|:.|:::|.......|..         |
 Worm  1177 TAHGVR---------EEIKEQHFMMGGGNPSLKLKPYQIKGLEWMVSLFNNNLNG---------I 1223

  Fly   487 LAHCMGLGKTLQVVTLSHTLLVNTRRTGVDRVLIISPLSTVNNWAREFTSWMKFANRNDIEVYDI 551
            ||..||||||:|.:... |.|:..::|. ...|:|.|||||.||..||..|.  ||     |:.|
 Worm  1224 LADEMGLGKTIQTIAFI-TYLMEIKKTS-GPFLVIVPLSTVPNWQNEFDKWA--AN-----VHLI 1279

  Fly   552 SRYKDKPTRIFKLNEWFNEGGVCILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDLVVCDE 616
            :....|.||  |:.|...:.|...:....:..:..|||  |..|.|.:.|           :.||
 Worm  1280 AYKGPKETR--KVFEPIIKSGKFNVLLTTFEYVIREKA--LLGKLRWKYM-----------IIDE 1329

  Fly   617 GHLLKNEKTSISKAV-TRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFVNPI 680
            ||.|||:...:::.: ||.:.:||:::|||||||.|.|.:.::.|:.|::..:...:...|..|.
 Worm  1330 GHRLKNQHCKLTEMLNTRFQCQRRLLITGTPLQNKLPELWALLNFLLPSIFSSCSTFEQWFNAPF 1394

  Fly   681 -TNGQYTDSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKLYG 744
             |.|:..:.|:.:..|:..|   |||:|...:.||....:...||.|.|:||...:|.||:.||.
 Worm  1395 ATTGEKVELTQEETMLIIRR---LHKVLRPFLLRRLKKEVESELPDKMEFVVRCDMSALQKVLYK 1456

  Fly   745 YYMTTHREQSGGDVVGK---GARLFQDFQ-DLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGF 805
            :.      |.|..:.||   |::..::.. .||::..||                         |
 Worm  1457 HM------QKGLLLDGKTNTGSKSLRNTMIHLRKLCNHP-------------------------F 1490

  Fly   806 ICDETDEDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSDLEMLGGLGGG 870
            :.:..:|         ||..|
 Worm  1491 LFENVEE---------SCRNF-------------------------------------------- 1502

  Fly   871 SSVQKDDPSEWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLS 935
                      |...|:...:|..|  |.||.:|.|:|.:.:|.|.::|:|.|....:.::|.||:
 Worm  1503 ----------WDARFISAVDLYRV--SGKLELLSRILPKLQATGHRVLMFFQMTSMMTIVEDFLA 1555

  Fly   936 LVDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAG 1000
                       .|.:           .|.|||||...::|.|:..:| |..|....||::|||||
 Worm  1556 -----------GGTI-----------QYLRLDGSTKPDERGALLDKF-NAPNSEYFLFMLSTRAG 1597

  Fly  1001 GLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAKQAT 1065
            |||:||..|:.|:|||..|||..|.|:..|.:|.||.....::|||...::|:|:......|...
 Worm  1598 GLGLNLQTADTVIIFDSDWNPHQDMQAQDRAHRIGQKAEVRVFRLITANSVEEKILAAARYKLNV 1662

  Fly  1066 AKRVIDEQQISRHYNQTDLMELYSYELKPSTE-REMPILPKDRLFAEILTEHEKLIFKYHEHDSL 1129
            .::||...:........:..|:....:|...| .|...:|.|....:||:..|:....:.:
 Worm  1663 DEKVIQAGKFDNRSTGAERREILENIIKTENESEEDEEVPNDEDINDILSRSEEEFELFQK---- 1723

  Fly  1130 LEQEEHENLTEEERKS 1145
            ::||..||  |:.:|:
 Worm  1724 MDQERFEN--EQAQKA 1737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	66/346 (19%)
		HepA	<382..1071	CDD:440319	184/695 (26%)
		DEXHc_ATRX	455..699	CDD:350826	77/245 (31%)
pqn-15	NP_001367558.1	Med15	<1..>288	CDD:312941
		Med15	<372..>592	CDD:312941
		HSA	1011..1083	CDD:214727	18/80 (23%)
		PLN03142	1062..>1726	CDD:215601	216/857 (25%)
		SnAC	1727..1799	CDD:464219	5/13 (38%)