Protein Alignment XNP and chd-1

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_491994.2
• Gene: chd-1 / 172432
• WormBaseID: WBGene00010369
• Length: 1461
• Species: Caenorhabditis elegans
• Alignment Length: 1241
• Identity: 285/1241 - (22%)
• Similarity: 477/1241 - (38%)
• Gaps: 371/1241 - (29%)

  Fly    20 DDSNSSSVSRRESATESKSASESESSPPRSNTKQSRTHKNVKA-SGKATVSSSSDSDQAVANSSA 83
            :.|.|||.|..|...::......|.:|..::|.:....|...| |.:::...|.|||.|..|||:
 Worm     3 NQSESSSGSDAEPDEKTDEPVREEENPEGNSTSEDNDEKEKAADSPESSSDQSDDSDDASENSSS 67

  Fly    84 NDEEKEPVCKIRIVPLEKLLASPKTKERPSRGSQQKNVTINDSSDEEPLKGSKLVLPARKSRNKN 148
            : |..||              :||.|...:||.        |:...:.|:.......:::|:.:
 Worm    68 S-EPDEP--------------APKKKNNNNRGM--------DAETRKLLENENYFRRSKRSKRQ- 108

  Fly   149 ASIIELSDSEEVDEEEESLLVAIPLPKEAQQTKPEKNSSKASKESIEKRQKAQKEATTSSARAIR 213
                   |....|..|||           |.::.:.:..:..:.::.|:...|.:...|..:. :
 Worm   109 -------DDSPSDNSEES-----------QSSEDDWDDRRKPRRTVTKKVVKQTKKAVSVVKR-K 154

  Fly   214 SVNGTRRGSLSSERSSRASSSRAESPPRPKRCVVRLKRVSLPKTKPAQKPKKMSSDSEE------ 272
            ||.|....:..:...........|....|              ..||:.|..::...|.
 Worm   155 SVKGNVNYAEKNSDDDIDDDDVLEWDEEP--------------AVPAEGPAILTETVERVIKWRH 205

  Fly   273 -------AATTSKKSRQRRSKSESEADSDYEAPAAEEEEEEERKSSG---------DEEEAA--N 319
                   :|||......:       .|.:.:.|..:.|::...|.:|         .|...|  |
 Worm   206 GVPGATGSATTCYNIADK-------GDPNDQIPGDKTEQQFFVKWTGWSHLHNTWESENSLALMN 263

  Fly   320 SSDSEVMPQRKRRRKKSESDKGSSD------FEPEE-------KQKKKGRKRIKKTSSGESDGDG 371
            :...:.:....:::|:.|..|.|:|      ||.|:       ::.||..:.:...:|.:...||
 Worm   264 AKGLKKVQNYVKKQKEVEMWKRSADKEYIEFFECEQQMAEELCEEYKKVERVVAHQTSRDRAADG 328

  Fly   372 DDDKQKNKRKHIRKIIKTKDL---DLTTKEAAKEEDDRRKRIEDRQKLYNRI-FVKSESVEINEL 432
            .        .....:||...|   |.|.      ||::....|..:..|:|| .:||.:...|.|
 Worm   329 S--------MATEYLIKWSGLPYSDCTW------EDEKMVAPEQIKAYYHRIENLKSPNKNSNVL 379

  Fly   433 VL--DFDE-ESKKALLQVDKGLLKKLKPHQVAGVKFM---WDACFETLKESQEKPGSGCILAHCM 491
            ..  .|:: ||....|:.|.....||:.:|:.|:.:|   |  |          .|:..|||..|
 Worm   380 RKRPKFEKFESMPDFLKTDGESTHKLRDYQLEGLNWMVYAW--C----------KGNSSILADEM 432

  Fly   492 GLGKTLQVVTLSHTLLVNTRRTGVDRVLIISPLSTVNNWAREFTSWMKFANRNDIEVY---DISR 553
            |||||:|.::|..:|.......|  ..|::.||||:..|.:||..|   |...::.||   .:||
 Worm   433 GLGKTIQSISLLASLFHRYDLAG--PYLVVVPLSTMAAWQKEFAQW---APEMNLVVYMGDVVSR 492

  Fly   554 YKDKPTRIFKLNEWFNEGGV------CILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDLV 612
                  .:.:..||| .||.      .||  ..|.||..:||           ..:.:|....||
 Worm   493 ------DMIRQYEWF-VGGTKKMKINAIL--TTYEILLKDKA-----------FLSSIDWAALLV 537

  Fly   613 VCDEGHLLKNEKTSISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRFV 677
              ||.|.|||:::.:.|::|:.|...::::|||||||:|:|.:.::.|:.|.....::|:
 Worm   538 --DEAHRLKNDESLLYKSLTQFRFNHKLLITGTPLQNSLKELWALLHFIMPEKFDCWEEF----- 595

  Fly   678 NPITNGQYTDSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQKL 742
                ...:.:|..:.:       ..|||.||..:.||....:...||||.|.::...::..|::.
 Worm   596 ----ETAHNESNHKGI-------SALHKKLEPFLLRRVKKDVEKSLPPKTEQILRVDMTAHQKQF 649

  Fly   743 YGYYMT-THREQSGGDVVGKGARLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDMEGFI 806
            |.:.:| .:||.|.| |.|..........:|::...| .:|....|::.       ||
 Worm   650 YKWILTKNYRELSKG-VKGSINGFVNLVMELKKCCNH-ASLTRQYDHIY-------DD------- 698

  Fly   807 CDETDEDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSDLEMLGGLGGGS 871
                                 :...:..|..|||
 Worm   699 ---------------------AQGRLQQLLKSSG------------------------------- 711

  Fly   872 SVQKDDPSEWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSL 936
                                       ||::|.:||.:.:..|.::|:|||.:..||:::.:|.|
 Worm   712 ---------------------------KLILLDKLLCRLKDKGHRVLIFSQMVMMLDILQEYLQL 749

  Fly   937 VDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFN--NITNLRARLFLISTRA 999
                 :.:..:                 |||||...:.|:.....:|  ..|:.   .||:||||
 Worm   750 -----RRFPSQ-----------------RLDGSMRADLRKQALDHYNAPGSTDF---AFLLSTRA 789

  Fly  1000 GGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQ----- 1059
            |||||||..|:.|:|||..|||.:|.|::.|.:|.||.|...||||:..|::|:::.||.
 Worm   790 GGLGINLATADTVIIFDSDWNPQNDLQAMSRAHRIGQTKTVNIYRLVTKGSVEEEIVERAKRKLV 854

  Fly  1060 ----------------VAKQATAKRVI--DEQQISRHYNQTDLMELYSYEL---KPSTEREMPIL 1103
                            ::|.|||...:  |:|::|.      :::..:.||   |...|:| |.:
 Worm   855 LDHLVIQRMDTTGKTVLSKNATASGSVPFDKQELSA------ILKFGAVELFKEKEGEEQE-PEV 912

  Fly  1104 PKDRLF---------AEILTEHEKL-IFKY------HEHD---------SLLEQEEHENLTEEER 1143
            ..||:.         .|::.|:|.| .|||      .|.|         :::.:|:...:.||||
 Worm   913 DIDRILMGAETREAEEEVMKENELLSSFKYANFAIDEEKDIAAATDEWAAIIPEEDRNRILEEER 977

  Fly  1144 KSAWAE 1149
            ....||
 Worm   978 MKELAE 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	59/330 (18%)
		HepA	<382..1071	CDD:440319	185/733 (25%)
		DEXHc_ATRX	455..699	CDD:350826	71/255 (28%)
chd-1	NP_491994.2	CD1_tandem_CHD1-2_like	194..275	CDD:349313	12/87 (14%)
		CD2_tandem	308..363	CDD:349306	13/68 (19%)
		PLN03142	404..1245	CDD:215601	192/762 (25%)
		DUF4208	1298..1367	CDD:464035