Protein Alignment XNP and Smarca4

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: XP_063120900.1
• Gene: Smarca4 / 171379
• RGDID: 621728
• Length: 1650
• Species: Rattus norvegicus
• Alignment Length: 1323
• Identity: 299/1323 - (22%)
• Similarity: 479/1323 - (36%)
• Gaps: 416/1323 - (31%)

  Fly     6 PNARHTDAATPLTTDDS--NSSSVSRRESATESKSASESESSPPRSNT---------------KQ 53
            |.....:||.|.:|...  ......|...|..:...:.|...||::.:               ||
  Rat   285 PEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPLVPLHQKQ 349

  Fly    54 SRTHKNVKASGKATVSSSSDSDQAVANSSANDEEKEPVCKIRIVPLEKLLASPKTKERPSRGSQQ 118
            ||.....|..|...|....:.:..:....|:          ||..||.|..|       ..|..:
  Rat   350 SRITPIQKPRGLDPVEILQEREYRLQARIAH----------RIQELENLPGS-------LAGDLR 397

  Fly   119 KNVTINDSSDEEPLKGSKLVLPARKSRNKNASIIELSDSEEV------DEEEESLLVAIPLPKEA 177
            ...||.       ||..:|:...|:.|            :||      |...|:.|.|    |..
  Rat   398 TKATIE-------LKALRLLNFQRQLR------------QEVVVCMRRDTALETALNA----KAY 439

  Fly   178 QQTKPEKNSSKASKESIEKRQKAQKE------------ATTSSARAIRSVNGTRRGSL------- 223
            :::|.:........|.:||:||.::|            :....|:..|..:.:..|.|
  Rat   440 KRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFREYHRSVTGKLQKLTKAV 504

  Fly   224 -----SSERSSRASSSRAESPPRPKRCVVRLKRV------SLPKTKPAQKPKKMS-----SD--- 269
                 ::||..:..:.|.|..        |::|:      ...|....:|.|:::     :|
  Rat   505 ATYHANTEREQKKENERIEKE--------RMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYV 561

  Fly   270 --------SEEAATTSKKSRQRRSKSESEADSDYEAPA----AEEEEEEERKS------------ 310
                    ..:||..:|:.::::.|.::| :::.:.||    .|..:|..:.|
  Rat   562 ANLTELVRQHKAAQVAKEKKKKKKKKKAE-NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESG 625

  Fly   311 ---SGDEEEAANSSDS--------EVMPQRKRRRKKSESDKGSSDFEPEEKQKKKGRKRIKKTSS 364
               :|.:...|...::        ||.|       :|:|::..|:.|.||:::::.:.....|..
  Rat   626 KILTGTDAPKAGQLEAWLEMNPGYEVAP-------RSDSEESGSEEEEEEEEEEQPQPAQPPTLP 683

  Fly   365 GES-----DGDGDDDKQKNKRKHIRKIIKTKDLDLTTKEAAKEEDDRRKRIEDR-----QKLYNR 419
            .|.     |.|.||..:.:.|..|              |.||::.|....:...     |..|..
  Rat   684 VEEKKKIPDPDSDDVSEVDARHII--------------ENAKQDVDDEYGVSQALARGLQSYYAV 734

  Fly   420 IFVKSESVEINELVLDFDEESKKALLQVDKGLLKKLKPHQVAGVKFMWDACFETLKESQEKPGSG 484
            ....:|.|:            |::.|.|: |:||:   :|:.|::::.......|..
  Rat   735 AHAVTERVD------------KQSALMVN-GVLKQ---YQIKGLEWLVSLYNNNLNG-------- 775

  Fly   485 CILAHCMGLGKTLQVVTLSHTLLVNTRRTGVDRVLIISPLSTVNNWAREFTSWMKFANRNDIEVY 549
             |||..||||||:|.:.|...|:.:.|..|  ..|||.||||::|||.||..|..       .|.
  Rat   776 -ILADEMGLGKTIQTIALITYLMEHKRING--PFLIIVPLSTLSNWAYEFDKWAP-------SVV 830

  Fly   550 DISRYKDKPT--RIFKLNEWFNEGGVCILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDLV 612
            .:| ||..|.  |.|.......:..|.:..|: |.|    |.|.:..|.|.:.|
  Rat   831 KVS-YKGSPAARRAFVPQLRSGKFNVLLTTYE-YII----KDKHILAKIRWKYM----------- 878

  Fly   613 VCDEGHLLKNEKTSISKAV-TRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLL---GTYKEYM 673
            :.||||.:||....:::.: |.....||::||||||||.|.|.:.::.|:.|.:.   .|::::.
  Rat   879 IVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWF 943

  Fly   674 NRFVNPIT-NGQYTDSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSE 737
            |.   |.. .|:..|..|.:..|:..|   |||:|...:.||....:...||.|.|||:...:|.
  Rat   944 NA---PFAMTGEKVDLNEEETILIIRR---LHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSA 1002

  Fly   738 LQQKLY------GYYMTTHREQSGGDVVGKGA--RLFQDFQDLRRIWTHPMNLRVNSDNVIAKRL 794
            ||:.||      |..:|...|:   |..|||.  .|......||:|..||
  Rat  1003 LQRVLYRHMQAKGVLLTDGSEK---DKKGKGGTKTLMNTIMQLRKICNHP--------------- 1049

  Fly   795 LSNDDSDMEGFICDETDEDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDS 859
                      ::....:|                                              |
  Rat  1050 ----------YMFQHIEE----------------------------------------------S 1058

  Fly   860 DLEMLGGLGGGSSVQKDDPSEWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSL 924
            ..|.||..||               .|:..:|...  |.|..:|.|:|.:..|...|:|:|.|..
  Rat  1059 FSEHLGFTGG---------------IVQGLDLYRA--SGKFELLDRILPKLRATNHKVLLFCQMT 1106

  Fly   925 QSLDVIEHFLSLVDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLR 989
            ..:.::|.:          :.:.|    ||        |.||||:...|.|..:.|.||. ....
  Rat  1107 SLMTIMEDY----------FAYRG----FK--------YLRLDGTTKAEDRGMLLKTFNE-PGSE 1148

  Fly   990 ARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQK 1054
            ..:||:||||||||:||.:|:.|:|||..|||..|.|:..|.:|.||.....:.||..:.::|:|
  Rat  1149 YFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEK 1213

  Fly  1055 VYERQVAKQATAKRVID----EQQISRHYNQTDLMELYSYE------------------------ 1091
            :......|....::||.    :|:.|.|..:..|..:..:|
  Rat  1214 ILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPP 1278

  Fly  1092 --LKPSTEREMPI-----LPKDRLFAEILTEHEKLIFKYHEHDSLLEQEEHEN------LTEEER 1143
              :.|..| |.|:     :|.|....:::..||:....:...|....:||..|      |.||:.
  Rat  1279 AGVNPDLE-EPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDE 1342

  Fly  1144 KSAW------------AEYEAEK 1154
            ..:|            .|.|.||
  Rat  1343 LPSWIIKDDAEVERLTCEEEEEK 1365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	65/369 (18%)
		HepA	<382..1071	CDD:440319	185/708 (26%)
		DEXHc_ATRX	455..699	CDD:350826	74/250 (30%)
Smarca4	XP_063120900.1	None