Protein Alignment XNP and lds

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: XP_061511887.1
• Gene: lds / 1280703
• VectorBaseID: AGAMI1_003319
• Length: 1197
• Species: Anopheles gambiae
• Alignment Length: 1300
• Identity: 284/1300 - (21%)
• Similarity: 468/1300 - (36%)
• Gaps: 404/1300 - (31%)

  Fly    11 TDAATPLTTDDSNSSSVSRRESATESKSA------------------SESESSPPRSNTKQSRTH 57
            ::|.........|||||...|...|.:|.                  :|||||......::.:..
Mosquito    41 SEAMNSSAASSPNSSSVVSSEEEEEEESVVRQMKKRQSVRMSLHPIHAESESSDEDETKEEGQDE 105

  Fly    58 KN-VKASGKATVSSSSDSDQAVANSSANDEEKE-----PVCKIR---IVPLEKLLASPKTKERPS 113
            .| |.|:....:.:|.|.|        .:||.|     |..::.   |.|.|    :.:.::.|:
Mosquito   106 SNDVSAAAGKLLLTSDDED--------GEEEVERRAYSPATRMSIHGIAPAE----TTEDEDTPT 158

  Fly   114 RG-----------------SQQKNVTINDSSDEEPLKGSKLVLPARKSRNKNASIIELSDSEEVD 161
            .|                 .|:||:.|:|..:||..|           |::|........:...:
Mosquito   159 GGGSDGGSDDDEEIIAVPRKQRKNLIISDDEEEEDRK-----------RSRNNMSFNADGTPRPN 212

  Fly   162 EEEESLLVAIPLPKEAQQTKPEKNSS-------KASKESIEKRQKAQKEATTSSAR---AIRSVN 216
            .:..:|....||.:|.|::...|.||       :.|.|.:::|::::.|.:....|   ::|:..
Mosquito   213 PKRRNLSTTSPLEQEEQESVNTKLSSSLKSDEMERSSEQVDEREQSRGELSFIGGRHSISMRASI 277

  Fly   217 GTR-----------RGSLSSERSSRASSSRAESPPRPKRCVVRLKRVSLPKTKPAQKPKKMSSDS 270
            |.:           .|.:::..:..||:..|:||.:                :.|...:|:  ||
Mosquito   278 GEKLSSTHIGEMDPLGPMANVETVFASAENAQSPIK----------------EGAHSSEKV--DS 324

  Fly   271 EEAATTSKKSRQRRSKSE-----SEADSDYEAPAAEEEE-------------------------- 304
            ...|.....|.:...|||     |.:|.|.|....||..
Mosquito   325 NSPAKDDSSSVRLIEKSEEILCLSSSDDDGEVTFVEETRPSIDVKTRPQALVQPTITSFVRSQDT 389

  Fly   305 -EEERKSSGDEEEA-----ANSSDSEVMPQRKRRRKKSESDKG-----------------SSDFE 346
             ::.::.|..|.:|     |......||.....|......|||                 |.|.|
Mosquito   390 AQQRQRVSQSEYDAKVRRMAELKSQVVMIDNVMRNSAKLPDKGAGLVRRLAEVKSQIFELSKDIE 454

  Fly   347 PEEKQKKKGRKRIKKTSSGESDGD--GDDDKQKNKRKHIR-KIIKTKDLDLTTKEAAKEEDDRRK 408
            .......||   ||||.....|.:  |.|.|.: ...||. ..||....|:..:...|:    ..
Mosquito   455 MTRATPSKG---IKKTIQRNFDENISGGDTKPR-PADHISWDTIKRATDDIQPRHTGKQ----GI 511

  Fly   409 RIEDRQKL--YNRIFVKSESVEINELVLDFDEESKKALLQVDKGLLKKLKPHQVAGVKFM-WDAC 470
            ...:.|||  .:|:....:|:|..        .|:..|....|.|..:|..||...:.:| |
Mosquito   512 ATFENQKLLTMDRLETLHKSIETC--------PSEDTLADPPKLLKIELMDHQRHALAWMLW--- 565

  Fly   471 FETLKESQEKPGSGCILAHCMGLGKTLQVVTL----------------------------SHTLL 507
                :|:| ||..| |||..|||||||.:::|                            :|...
Mosquito   566 ----RETQ-KPRGG-ILADDMGLGKTLSMISLVLKSAELDPDGEQLERASESEDDEGDEENHNPN 624

  Fly   508 VNTRRTG-----VDRVLIISPLSTVNNWAREFTSWMKFANRNDIE--VYDISRYKDKPTRIFKLN 565
            ...:..|     ....||:.|.|.:..|..|.|:.:|   ||.:.  |:..::.:.||..:.|
Mosquito   625 GGWKSKGRKDYYAGGTLIVCPASLMRQWEGEITNRVK---RNSLAVCVHHGTQRESKPRHLAK-- 684

  Fly   566 EWFNEGGVCILGYDM----YRILANEKAKGLRKKQREQLMQALVDPGPDLVVCDEGHLLKNEKTS 626
                        ||:    |.:::.|...|..:.     ...:.....:.::.||.|:::|.|::
Mosquito   685 ------------YDVVITTYNLVSRESRAGTARG-----ASGVYGVNWERIILDEAHVIRNHKSA 732

  Fly   627 ISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVK--P-NLLGTYKEYMNR-------FVNPIT 681
            :|:|...::.:.|.:|||||:||...:.|.:::|::  | |.|..:|.:::.       .:|.|.
Mosquito   733 MSEACCGLKGRYRWLLTGTPIQNKEMDVYALMKFLRCTPFNDLVHWKRWIDNKTAGGAMRLNTIM 797

  Fly   682 NGQYTDSTERDL-------------------RLMKHRSHILHKLLEGCIQRRDYS--VLAPYL-- 723
            .......|::.|                   :|.|...::..|:|.       ||  :.|.:|
Mosquito   798 KSIMLRRTKKQLQERGALTSLPSKTIEIIEVQLEKDEMNVYQKVLM-------YSKHLFAQFLHQ 855

  Fly   724 -PPKHEYVVY------TTLSE------------LQQKLYGYYMTTHREQSGGDVVGKGARLFQDF 769
             ..|...:.|      .|.|:            :.|||    .:.|..:.|.:|  |..::....
Mosquito   856 RAEKEHAINYGFGGARPTFSQRAHGGANQAFDKVHQKL----KSMHAAKDGSEV--KQHQILVLL 914

  Fly   770 QDLRRIWTHPMNLRVNSDNVIAKRLLSNDDS---DMEGFICDETDEDEAASNSSDSCETFKSDAS 831
            ..||::..||         .:...:||:||.   ||.|     ..|:|.         :|.::..
Mosquito   915 LRLRQVCCHP---------GLIYEMLSDDDQSNLDMTG-----GGEEEG---------SFGAEVD 956

  Fly   832 MSG----------LAASSGKVKKRKTRNGNAGGGDSDSDLEMLGGLGGGSSVQKDDPSEWWKP-- 884
            :.|          ||....||    ..||.|.|...:..|.:        |.|.|.|....|.
Mosquito   957 LLGALNKLKLSDVLADHEAKV----AANGGADGSKQELSLNL--------SDQFDRPEAMAKAAS 1009

  Fly   885 ---------FVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSLQSLDVIEHFLSLVDSN 940
                     |..||..:.:..:.:|     |.::.....||.::.||....||::...||
Mosquito  1010 KVMLKSNPIFRIERPSSKIEKTMQL-----LEEKIFHTDDKAIIVSQWTSMLDILATHLS----- 1064

  Fly   941 TKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRARLFLISTRAGGLGIN 1005
            .:|..|                 ..|.|...|:.|..:...||..:. ::::.|:|..|||:|:|
Mosquito  1065 ERNVPF-----------------VSLTGKVQVKFRNDIVLDFNKPSG-KSKVMLLSLTAGGVGLN 1111

  Fly  1006 LVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKRVI 1070
            ||.||.:::.|..|||..:.|:..||||.||.||.||::.:...|:|||:...|..|...|..|:
Mosquito  1112 LVGANHLLLLDPHWNPQLEAQAQDRVYRVGQTKPVYIWKFMCAETVEQKIQALQEHKLGIADGVL 1176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	75/366 (20%)
		HepA	<382..1071	CDD:440319	186/807 (23%)
		DEXHc_ATRX	455..699	CDD:350826	69/312 (22%)
lds	XP_061511887.1	None