Protein Alignment XNP and LOC1269656

DIOPT Version :10

• Sequence 1: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: XP_061499833.1
• Gene: LOC1269656 / 1269656
• VectorBaseID: AGAMI1_004919
• Length: 3238
• Species: Anopheles gambiae
• Alignment Length: 2187
• Identity: 445/2187 - (20%)
• Similarity: 669/2187 - (30%)
• Gaps: 1059/2187 - (48%)

  Fly     3 KKNPNARHTDAATPLTTDDSNSSSVSRRESATESKSASESESSPPRSNTKQSRTHKNVKASG-KA 66
            |.|.::.:...:.|       |...|.|:|:..||:...|         |..|:..:..||| :|
Mosquito   419 KGNESSHYHHGSAP-------SGGSSGRKSSKASKAGDSS---------KHDRSGASTSASGSEA 467

  Fly    67 TVSSSSDSDQAVANSSAN---DEEKEPVCKIRIVPLEKLLASPKTKERPSRGSQQKNVTINDSSD 128
            |.:......|..|....:   .|:.:.:.:|.:.|:.|..|:.|     ||.|:.      :.::
Mosquito   468 TAADQHQQPQTSATQHMDFDISEKLKEMGEISVKPVSKTDANTK-----SRASEL------ECNE 521

  Fly   129 EEPLKGSKLVLPARKSRNKNASIIELSDSEEVD-----------------EEEESLLVAIPLPKE 176
            |..|:.:|.....||..|...:|.|:.|..::|                 :|::.::      :|
Mosquito   522 EISLEITKKDAAMRKVSNLRKNIKEVMDDNQLDASTLAAQRQELERLARVQEQQRII------RE 580

  Fly   177 AQ-QTKPEKNSSKASKESIEKRQ------KAQKEATTSSARAIRSVNGTRRGSLSSERSSRAS-- 232
            .| |...|:.::|..::.::..|      |:|:.:|:|:|     .:|:..|.::|....|..
Mosquito   581 VQRQLALERQTNKTEQKVMQFLQGHASILKSQQPSTSSTA-----ASGSGSGGVASTTPIRVGYV 640

  Fly   233 ----SSRAESPPRPKRCVVRLKRVSLPKT-----------------KPAQKPKKMSSDSEEAATT 276
                .:|.. ||:.::.::.....||..|                 .|:.....:.:.|..||.|
Mosquito   641 KNPFETRGR-PPKNRQLLISTATTSLLTTTTTTVAASTTAATSTNLTPSVSIAPVKASSVAAAVT 704

  Fly   277 -----SKKSRQRRSKSESEAD-SDYEAPAAEEEEEEERKSSGDEEEAANSSDSEV--MPQRKR-- 331
                 |.......|.|.|... ..:|.....|||.|..:...||:|   .||.||  :|::|.
Mosquito   705 PVGPPSTTIAASASPSPSLIPVRTFEEMVDSEEELEPEEEPEDEDE---DSDGEVIALPEKKEIV 766

  Fly   332 -RRKKSESD---KGSSDFEPEEKQKKKGRKRIKKTSSGESDGDGDDDKQKNKRKHIRKIIKTKD- 391
             ....|:.|   ....|.|||:                    :.|||.| |...|:.......|
Mosquito   767 TIDSSSDDDCIVLSDDDEEPED--------------------ESDDDPQ-NSGLHVNDAYNVPDE 810

  Fly   392 ---LDLTTKEAAKEEDDRRKRIEDRQKLYNRIFVKSESVEINELVLDFDEESKKALLQVDKGLLK 453
               :.:....|..|||               ||:..:...|
Mosquito   811 QGRVVINVGHADGEED---------------IFLAPQIARI------------------------ 836

  Fly   454 KLKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQVVTLSHTLLVNTRRTGVDRV 518
             :||||:.||:|::|...|:::......|.||||||.||||||||:|......|   |.|....|
Mosquito   837 -IKPHQIGGVRFLFDNIIESIERYDSSTGFGCILAHSMGLGKTLQLVCFCDIFL---RHTSSKTV 897

  Fly   519 LIISPLSTVNNWAREFTSWMKFANRNDIEVYDISRYKDKPTRIFKLN-----------------E 566
            |||.|::|:.||..||.:|:.    .|.|...:..:.:...|.|:::                 |
Mosquito   898 LIIMPINTLQNWLNEFNTWLP----EDAENSPLRNHGEVRPRNFRIHILNDSHKTLKSRSKVVLE 958

  Fly   567 WFNEGGVCILGYDMYRILANEKAKGLRKKQR--------------------EQLMQALVDPGPDL 611
            |...|||.::||:|||:|:.:|....:||::                    :.:.:|||.|||||
Mosquito   959 WARNGGVLLIGYEMYRLLSQKKMTKKKKKKKGVAVELEEEKESTEEQRNMFDDIHEALVKPGPDL 1023

  Fly   612 VVCDEGHLLKNEKTSISKAVTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEYMNRF 676
            |||||||.:||...|||.|:.::::|||:||||.||||||.||:||:.||:||.|||..|:.|.|
Mosquito  1024 VVCDEGHRIKNSHASISVALKQIKSKRRVVLTGYPLQNNLLEYWCMVDFVRPNYLGTKTEFSNMF 1088

  Fly   677 VNPITNGQYTDSTERDLRLMKHRSHILHKLLEGCIQRRDYSVLAPYLPPKHEYVVYTTLSELQQK 741
            ..||.|||..|||.:|::||::|:|:||.||.|.:|||.:|||...||.|.|||:...::|.|:|
Mosquito  1089 ERPIQNGQCIDSTPQDIKLMRYRAHVLHSLLLGFVQRRSHSVLQTSLPQKEEYVLLIRMTEFQRK 1153

  Fly   742 LYGYYMTTHREQSGGDVVGKGA--RLFQDFQDLRRIWTHP-------------MNLRVNS----- 786
            ||..:|        .|||...|  ...:.|....:||.||             ::|.:..
Mosquito  1154 LYSVFM--------NDVVRTKAVPNPLKAFAVCCKIWNHPDVLYNFLKQSERDLDLELEEPEPPP 1210

  Fly   787 --------------------------------DNVI----------------------------- 790
                                            |:.:
Mosquito  1211 VPGGVPGAVKPGEIPSTGITPATSGTVTPMEVDSAVAAVPGAIPGTANTMEVSPISSIVPSIGGP 1275

  Fly   791 -------------AKRLL----------------------------------------SNDDSDM 802
                         ||.|.                                        ||.:.|.
Mosquito  1276 AKPGRKNAAVPKPAKPLALKKDGTPRKPRTSKKATVATNKSQAVGKDGKMVPAATISPSNVNKDP 1340

  Fly   803 EGFICDET--------------------------------------------------------- 810
            ...:.|.|
Mosquito  1341 AAMMMDTTPGAPGGSADFPKMEGSGPDFGTEGGSSVKQEAGGAMYPQQADGMQYPGASGMGPSYP 1405

  Fly   811 ----------------------------------------------------------------- 810
                                                                             
Mosquito  1406 YQPYPGAGPMAPNHAYGSYGQGMNMMGGPDQSNVYGNTYANAGANGQYGSGSNQAGGPGGATDPY 1470

  Fly   811 -----------------------------------------------DEDEAASNSSDS------ 822
                                                           :..|..:||..|
Mosquito  1471 NGGYGNNYYRNDYTSSYNQSSAYGSAGNTSAAATGGYDHQSQYPYGANTSEGVANSQYSSNGSEP 1535

  Fly   823 ------CETFKSD-ASMSGLAA------------------------------------------- 837
                  ..::.|| |:|:|..:
Mosquito  1536 GIQNPQSNSYWSDSANMNGSNSYYDQQQQQQQQQQQQQQQPTPTNEANGGTGTPYPGYGAGYEGA 1600

  Fly   838 ------------------SSG-------------------------------------------- 840
                              |||
Mosquito  1601 NGGTQQQQQPPISTDQNGSSGMFNFPNAEQQSAAEAPSTVNPQSQTTPSYDNFATPETLPANGLP 1665

  Fly   841 KVKKRKTRNGN--AGGGDS---------------------------------------------- 857
            |....::.|||  |.|||:
Mosquito  1666 KWDAEQSSNGNHSAVGGDAELPQSQTAESAVTEQEATAASTTTPTTDAPLVVPAQSSAETNESNP 1730

  Fly   858 --------------------------------------------------DSDLEM--------- 863
                                                              |.:||:
Mosquito  1731 DAAAITQEQANAQYANQPSLEDLNDPVKPDLTGEKPPEIVGMDVKEIDKLDDELEIKQEIKQEKE 1795

  Fly   864 ---LGGLGGGSSVQ--------------------------------KDDP-------------SE 880
               :.|.....|||                                .|.|             ||
Mosquito  1796 VEDIKGEKETESVQVKQEEQDSVVVKNEIKVEENGEKIANDACGDMPDKPAGEVKEEEKLTESSE 1860

  Fly   881 WWKPF------------------------------------------------------------ 885
            ..||.
Mosquito  1861 DVKPIKKEELTEDVEIKQEDEQKPSTEGETIKSMEEKKVDEDSVVDKKEEIEIPIEKKEAADQEA 1925

  Fly   886 ---------------------------------------------VEEREL-------------- 891
                                                         |||:|.
Mosquito  1926 EEAKAKEEVEKVVEEDVKLIVKDADGEEKLKDDTTQLEEGEVVVKVEEKESPTADKDPLSTTSTT 1990

  Fly   892 ------------------------------------------------NNVHHSPKLLILLRLLQ 908
                                                            :.:.:|||:.|...:|:
Mosquito  1991 TSTTTSTTITTTTTTTTATAGTKEGKGKDAKDEIPYEWAFELMKGYIPDLLENSPKMDIFFCILE 2055

  Fly   909 QCEAIGDKLLVFSQSLQSLDVIEHFLSLVDSN----TKNYEFEGDVGDFKGCWTSGKDYFRLDGS 969
            :...:||:||||||||.:|::||.||   ..|    |:||            |.....|||||||
Mosquito  2056 ESIRLGDRLLVFSQSLLTLNLIERFL---QHNKIPGTENY------------WAKNISYFRLDGS 2105

  Fly   970 CSVEQREAMCKQFNNITNLRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRF 1034
            ...::||.:..:||  :|....|||:|||||.||||||.|||||:||.||||.||||::.||||:
Mosquito  2106 TVAQEREKLINEFN--SNPNVHLFLVSTRAGSLGINLVGANRVVVFDASWNPCHDTQAVCRVYRY 2168

  Fly  1035 GQIKPCYIYRLIAMGTMEQKVYERQVAKQATAKRVIDEQQISRHYNQTDLMELYSY------ELK 1093
            ||.|||::|||:....:|:|:|:||:.||..:.|::||.....|.:..::..| .|      |:|
Mosquito  2169 GQKKPCFVYRLVMDNCLEKKIYDRQINKQGMSDRIVDECNPDAHLSMKEITSL-CYDDGEDGEMK 2232

  Fly  1094 PSTEREMPILPKDRLFAEILTEH------EKLIFKYHEHDSLLEQEEHENLTEEERKSAWAEYEA 1152
            ..:|      .||: |.:|:.:|      :||......|:|||...:.:.|:..|::.|...||.
Mosquito  2233 DFSE------DKDK-FIDIVMQHLLESHSKKLTKAPFAHESLLIDRKEKKLSSAEKRQAQRGYEL 2290

  Fly  1153 EKTRTVQASQYMSYDRNAFGNQVMGQFGNASGSVTSNKIFGFRSDILLQLLNMKISKDHQELNQN 1217
            ||    ||:....|...:.|..... ...:.||:....:...|.        |:..    :.|:.
Mosquito  2291 EK----QAATKPQYSYTSMGTTYRA-IRTSDGSIIHRPVASVRP--------MQAG----DANKT 2338

  Fly  1218 QVIQLVPT-------------YLQQLYNEMNNGDPTMYKDLLNLHSNIV-----------HPSGM 1258
            ......||             ..|::...::...||...|    .||||           .|.|:
Mosquito  2339 TTTGARPTRWIAAEVWQRQGMTAQEMTLPIDVVIPTSSAD----KSNIVLKAGQKVMVLKSPKGI 2399

  Fly  1259 YM---NPLLYANQNPNAAGYNQGTGGVPPMAGGSVAHGPPAA 1297
            ||   :..:.|.:.....|.::.|   ||..||.::..|.||
Mosquito  2400 YMQLESGKIIAIRTAFKVGQSKET---PPAKGGIISTTPAAA 2438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XNP	NP_651398.1	PTZ00121	<173..>460	CDD:173412	67/334 (20%)
		HepA	<382..1071	CDD:440319	292/1476 (20%)
		DEXHc_ATRX	455..699	CDD:350826	116/280 (41%)
LOC1269656	XP_061499833.1	None