DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4553 and RRG9

DIOPT Version :9

Sequence 1:	NP_651396.1	Gene:	CG4553 / 43078	FlyBaseID:	FBgn0039336	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_014186.1	Gene:	RRG9 / 855508	SGDID:	S000005157	Length:	214	Species:	Saccharomyces cerevisiae

Alignment Length:	241	Identity:	52/241 - (21%)
Similarity:	96/241 - (39%)	Gaps:	59/241 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RMIQRGLHTARSCLLARAPRRANPGLGYQLEQLQEHPEKSSEASEDYADLESDFMDVQKTHRQYE 68
            |:..|..|    ||  |.....|...|:..:::.:...|||.:::::.:   ...|..|...:::
Yeast     5 RIACRSFH----CL--RCGPLLNENRGWSSKKIIKLVNKSSLSNKEFTE---KVRDGTKDIPEWK 60

  Fly    69 REQQQHRDRIRQFMIKHKYFRDAKLPNLLLHAEKEQMRLLHERDPEEWSVERLAESFPATPDIVQ 133
            :::...|.:::.        :....|..:...:.|.:|||....| |.:...||:.|..:|:.|:
Yeast    61 KQKMAVRKKLQG--------QRWNPPKKISQEQMEALRLLKFNFP-ELTASDLADRFKISPEAVR 116

  Fly   134 KILRAKWR-------------PRSVQRI-----RSHDETVIKNWQLLGTGK---GDFSIPPSLLQ 177
            :||::.|:             .|..:||     |..|...:.| |::.:.|   |..|..|.|:.
Yeast   117 RILKSNWKRTDEENNNTYERWKRRGERIKEMYQRKEDADFVSN-QIVTSRKIILGSNSNSPELIA 180

  Fly   178 HLQKFAERRWQDLRELKIQDWPTKSQLPTPQGNEFRKL-----LGS 218
                      :::|..|    |.|....||:.....||     |||
Yeast   181 ----------RNVRTFK----PFKPNNSTPEKKNTNKLYILKHLGS 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4553	NP_651396.1	Neugrin	103..>157	CDD:283952	19/71 (27%)
RRG9	NP_014186.1	Neugrin	77..>121	CDD:399425	14/44 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13475
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100