Protein Alignment CG4553 and Ngrn

DIOPT Version :10

• Sequence 1: NP_651396.1
• Gene: CG4553 / 43078
• FlyBaseID: FBgn0039336
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_113552.3
• Gene: Ngrn / 83485
• MGIID: 1933212
• Length: 293
• Species: Mus musculus
• Alignment Length: 328
• Identity: 70/328 - (21%)
• Similarity: 125/328 - (38%)
• Gaps: 98/328 - (29%)

  Fly    52 DLESDFMDVQKTHRQYEREQQQHRDRIRQFMIKHKYFRDAKLPNLLLHAEKEQMRLLHERDPEEW 116
            |.:||:...::..::.|...::.:..:|...|:.:.......|..|.....||:|.||:...|.|
Mouse    38 DPDSDWEPEERELQEVESALKRQKKAMRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHKEFAESW 102

  Fly   117 SVERLAESFPATPDIVQKILRAKWRPRSVQRIRSHDETVIKNWQLLGTGKGDFSIPPSLLQHLQK 181
            ||.||||.|..:.|:::::|::|:.|...|::| .|:.|:|        |..|:
Mouse   103 SVPRLAEGFDVSTDVIRRVLKSKFVPTLEQKLR-QDQKVLK--------KAGFT----------- 147

  Fly   182 FAERRWQDLRELKIQDWPTKSQLPTPQ--------GNEFRKLLGS----SSKTTEEMPTPQIPSG 234
                     ||:        .|||..:        |.....||.:    |||:.......::...
Mouse   148 ---------REI--------GQLPVSEDTLKALSAGRSVSGLLMAGDEVSSKSQNHSTALKVAKS 195

  Fly   235 YEAPPSAAEDETYLLDKIRNKKKMRLQELKELQLVESAPAV--PEEMKRPIENPS------GTGF 291
            :   |.:.:.:     |.|..:..|:|.|:| .||.:..|:  ..|:::...:.|      |:..
Mouse   196 H---PHSTDAQ-----KKREGRDKRIQVLEE-SLVPATTALGHQRELQKSATSDSEATGRAGSDT 251

  Fly   292 LPSFV------PKFASSEIVISAADQRKYEITQVKTRIVIPRKLHRQGATYRVEDAYYDDDGELL 350
            |||.|      |.....:...|...||.::                          ::|.:|..|
Mouse   252 LPSAVLLEELKPGEPGDQSFSSKVVQRGHD--------------------------FFDSNGNFL 290

  Fly   351 YRV 353
            ||:
Mouse   291 YRI 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4553	NP_651396.1	Neugrin	103..>176	CDD:428925	25/72 (35%)
Ngrn	NP_113552.3	Neugrin	73..293	CDD:428925	63/291 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	177..210		6/40 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	224..254		5/29 (17%)