DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4553 and Ngrn

DIOPT Version :9

Sequence 1:	NP_651396.1	Gene:	CG4553 / 43078	FlyBaseID:	FBgn0039336	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_001029072.2	Gene:	Ngrn / 499191	RGDID:	1583734	Length:	293	Species:	Rattus norvegicus

Alignment Length:	350	Identity:	78/350 - (22%)
Similarity:	137/350 - (39%)	Gaps:	105/350 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 ANPGLGYQLEQLQEHPEKSSEASEDYADLESDFMDVQKTHRQYEREQQQHR-DRIRQFMIKHKYF 88
            |.||      .:...|:..|       |.|.:..::|:.....:|:::..| .:||:.|     .
  Rat    28 AGPG------SISREPDPDS-------DWEPEERELQEVESALKRQKKAMRFQKIRRQM-----E 74

  Fly    89 RDAKLPNLLLHAEKEQMRLLHERDPEEWSVERLAESFPATPDIVQKILRAKWRPRSVQRIRSHDE 153
            .....|..|.....||:|.||:...|.|||.||||.|..:.|:::::|::|:.|...|::: .|:
  Rat    75 APGAPPRTLTWEAMEQIRYLHKEFAESWSVPRLAEGFDVSTDVIRRVLKSKFIPTLEQKLK-QDQ 138

  Fly   154 TVIKN-------WQLLGTGKGDFSIPPSLLQHLQKFAERRWQDLRELKIQDWPTKSQLPTPQGNE 211
            .|:|.       |||   ...:.::.|....|                    |....|..| |:|
  Rat   139 KVLKKAGITRVVWQL---PVSEDTLKPLSAGH--------------------PMSGPLLMP-GDE 179

  Fly   212 FRKLLGSSSKTTEEMPTPQIPSGYEAPPSAAEDETYLLDKIRNKKKMRLQELKELQLVESAPAVP 276
                :.|:|:|...  ..::.|  .||.:.|:       |.|.:|..|::.|.| .||.:..|:.
  Rat   180 ----VSSNSQTHSR--ALKVKS--NAPSAEAQ-------KKREEKNKRIRVLAE-SLVPTTTALG 228

  Fly   277 EEMKRPIENPSGTGFLPSFVPKFASSEIVISAADQRKYEITQVKTRIVIP--RKLHR-------- 331
            .:.:               :.|:.:.:   |.||:|       ....::|  .||..
  Rat   229 HQRE---------------LQKYTTHD---SEADRR-------ANNHILPSVEKLEELEAGEPGD 268

  Fly   332 QGATYRVED---AYYDDDGELLYRV 353
            |..:.:|..   .::|.:|..|||:
  Rat   269 QNFSSKVVQKGREFFDSNGNFLYRI 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4553	NP_651396.1	Neugrin	103..>157	CDD:283952	21/53 (40%)
Ngrn	NP_001029072.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	25..48		7/32 (22%)
		Neugrin	73..293	CDD:283952	65/290 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	162..211		17/84 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D322069at33208
OrthoFinder	1	1.000	-	-		FOG0008328
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13475
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	4.070