Protein Alignment Vps33B and vps33a

DIOPT Version :10

• Sequence 1: NP_651395.1
• Gene: Vps33B / 43077
• FlyBaseID: FBgn0039335
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_012818531.1
• Gene: vps33a / 549689
• XenbaseID: XB-GENE-978483
• Length: 614
• Species: Xenopus tropicalis
• Alignment Length: 645
• Identity: 140/645 - (21%)
• Similarity: 271/645 - (42%)
• Gaps: 94/645 - (14%)

  Fly    19 KLCSILCSIPGKKELILEPDLIKPLEHVVTASWLKLKGIQRIYKHDAAQSLPRSADQVHIYMIRS 83
            :|...|....|.|.::.:..|..|...:...|.||...:::::...:. .||.|..:..|:.:|.
 Frog    35 ELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKSG-PLPSSDVKNIIFFVRP 98

  Fly    84 VLGTFQTLLKQLQPVASEEMPDISMKMYHIVCVPSCYSYFQTLLEQAGLYG-LVQLHHFNWDFIY 147
            .|.....:...:|   .||......:.::|:.||......:..|:..|:.| .:....:..:.|.
 Frog    99 RLELMDIIADNIQ---REERGRFPQRDFYILFVPRRSILCEQRLKDLGVLGSFMHRDEYRLNLIP 160

  Fly   148 FDQGVLSLELPNLYECLYLQKNTSPLPAVAQSLRLLQMICGQPSLILSFG----HHSSQLMQMAK 208
            ||..:||:|..|.::..||:.:.:.|...|:.|..||.:.|....|...|    |.::.:::|.:
 Frog   161 FDGDLLSMESENAFKECYLENDQTSLYQAAKGLTTLQSLYGTIPQICGKGECARHVANMMIRMKR 225

  Fly   209 TLGKLPAPTNPPDYGGWLVIDRDKDYPASLLTPAIYAGLLLEVFEHSSGEILVDNSKNKIRSQRV 273
            .||.......|. :...|::||:.|....|.|...|.||:.||:.       :.||..|:..::
 Frog   226 ELGGSQNQITPV-FDTLLLLDRNVDLLTPLATQLTYEGLIDEVYG-------IQNSHVKLPPEK- 281

  Fly   274 ELLQGKKSKIGVNSASKPCSIRLNSTSDEIYGDNRYKRFAQVSSLIHAQVKALGLELQ-KLNDMQ 337
             ....|:.:.|.:..::|..:.||| ::|:|.:.|.|.|..|.|::..:.|.:....: :.|...
 Frog   282 -FAPKKQGEGGKDLPTEPKKLLLNS-AEELYAEIRDKNFNAVGSVLSKKAKIISAAFEGRHNAKT 344

  Fly   338 LDEMHDYVARKLPKLTELKSKVLRHLNASEIVIQMMGN---FRKLQTLEEDILNNDSRKRLLSEI 399
            :.|:..:|: :||.:...|:.:..|.:.:|::.::..:   |..| |:|::.::.....::...|
 Frog   345 VGEIKQFVS-QLPHMQAEKASLANHTSIAELIKEITTSEAFFDNL-TVEQEFMSGFDTDKVNPYI 407

  Fly   400 DELLTTDGQRFNTLRLLCLLHHC-VGVAPEELQIFARNYCNLFGHQELGVFQQLSQAGLLPPLVV 463
            ::.:.........|||:||...| .|:..:.|..:.|.....:|::.:.....|.:||||
 Frog   408 EDCIAKKDPIIKILRLVCLQSVCNTGLKQKVLDYYKREILQTYGYEHILTLHNLEKAGLL----- 467

  Fly   464 EKKAPTKLLSNLPLPKFQQTEFQANANRLKLLTSSGDGQDGGSSSKSQSSGLQTCPSFVFNGTYI 528
                ..:..|....|..::|        |:|.....:.|:....            |:|::| |.
 Frog   468 ----KLQASSRNSYPTIRKT--------LRLWMDDVNEQNPNDI------------SYVYSG-YA 507

  Fly   529 PLVAQLCSIL-----------LKINSAEELSSKLGMIEGLHLHLDSGKITPKAYASQVKLNGVAD 582
            ||..:|..||           |||....:...:..:..||......|:            |.|
 Frog   508 PLSVRLAQILVRPGWRSIEEVLKILPGPQFEERQSLPPGLLKKRQQGE------------NKV-- 558

  Fly   583 QDMFPLRLRNLFVFIVGGASYAEIAACDFVAKLT--GAQITVASDSLMAGSDLIATAFNR 640
                      :.||.:||.::|||||..|::::.  |.:..:|:..|::|:..|.:...:
 Frog   559 ----------ILVFFLGGVTFAEIAALRFLSQMEDGGTEYIIATTKLISGTTWIKSLMEK 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps33B	NP_651395.1	Sec1	31..634	CDD:460020	136/625 (22%)
vps33a	XP_012818531.1	Sec1	47..604	CDD:460020	137/627 (22%)