Protein Alignment Vps33B and car

DIOPT Version :10

• Sequence 1: NP_651395.1
• Gene: Vps33B / 43077
• FlyBaseID: FBgn0039335
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Alignment Length: 666
• Identity: 150/666 - (22%)
• Similarity: 263/666 - (39%)
• Gaps: 108/666 - (16%)

  Fly     9 LQGFQLVAQEKLCSILCSIPGKKELILEPDLIKPLEHVVTASWLKLKGIQRIYKHDAAQSLPRSA 73
            ||..|..|..:|...|..|.|.|.::|:..:|.||:.|........:|| |:........|||..
  Fly    14 LQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGI-RLLALKPELHLPREV 77

  Fly    74 DQVHIYMIRSVLGTFQTLLKQLQPVASEEMPDISMKMYHIVCVP--SCYSYFQTLLEQAGLYG-L 135
            ..| :|::|..:    .|::||...........:.:.|||:..|  ||....|  ||.:|:.| .
  Fly    78 ANV-VYVMRPRV----ALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQ--LEVSGVLGSF 135

  Fly   136 VQLHHFNWDFIYFDQGVLSLELPNLYECLYLQKNTSPLPAVAQSLRLLQMICGQPSLILSFGHHS 200
            ..:....|:::..|..::|:|:||.:..:.:..:||.|...|..|..||.:.|:...|...|..:
  Fly   136 GNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGEFA 200

  Fly   201 SQLMQMAKTLGKLPAPTNPPDYG---GWLVIDRDKDYPASLLTPAIYAGLLLEVF---------- 252
            .::.:.||.||:........|.|   ..:::||..|..:.|.|...|.||:.|.:
  Fly   201 HRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLP 265

  Fly   253 --EHSSGEILVDNSKNKIRSQRVELLQGKKSKIGVNSASKPCSIRLNSTSDEIYGDNRYKRFAQV 315
              ...|...|.....:..|.:..:.|.|...|         .:|.|:| .:::|.:.|.|.|.:|
  Fly   266 AENFPSDGALPGGGGSGPRVEESQSLLGDTEK---------KTILLHS-GEQLYAELRNKHFNEV 320

  Fly   316 SSLIHAQVKALGLELQKLN-DMQLDEMHDYVARKLPKLTELKSKVLRHLNASEIVIQMMGNFRKL 379
            :.|:..:.:.:.:::...: |..:.|:..:|...||:|...|.....|...:.::.:.:...|..
  Fly   321 TKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFA 385

  Fly   380 QTL--EEDILNNDSRKRLLSEIDELLTTDGQRFNTLRLLCL-LHHCVGVAPEELQIFARNYCNLF 441
            ..|  |::.:......:..:.|::|:....:....|||:|: .|...|...:.|..:.|...:::
  Fly   386 DDLAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVY 450

  Fly   442 GHQELGVFQQLSQAGLLPPLVVEKKAPTKLLSNLPLPKFQQTEFQANANRLKLLTSSGDGQDGGS 506
            |.:.|.....|.::||| .|..|.:|.:.|...|.|......|.
  Fly   451 GLEVLLTISNLEKSGLL-HLQTESRAYSVLRKTLHLTVDDNVEI--------------------- 493

  Fly   507 SSKSQSSGLQTCPSFVFNGTYIPLVAQLCSILLKINSAEELSSKLGMIEGLHLHLDSGKITPKAY 571
                :...:....||     |.||.|::....||....:.|.|::..:.|           |...
  Fly   494 ----EPKDISYVHSF-----YAPLTARIVEHSLKPLGWQTLKSQINNLPG-----------PTFE 538

  Fly   572 ASQVKLNGVADQDM-----------FPLRLRNLFVFIVGGASYAEIAACDFVA--KLTGAQITVA 623
            ..|.:|.|:..:..           .|   |.:.|..|||.::|||||..|:|  :....:..:|
  Fly   539 DFQAQLVGIGGRHTVTTVSEGSLLNVP---RVVLVCFVGGCTFAEIAALRFLAAQEDNNVEFLIA 600

  Fly   624 S----------DSLMA 629
            :          ||||:
  Fly   601 TTKVVNKHSFLDSLMS 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps33B	NP_651395.1	Sec1	31..634	CDD:460020	142/644 (22%)
car	NP_001259707.1	Sec1	36..613	CDD:460020	138/639 (22%)