Protein Alignment Vps33B and Vps33B

DIOPT Version :10

• Sequence 1: NP_651395.1
• Gene: Vps33B / 43077
• FlyBaseID: FBgn0039335
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_321664.4
• Gene: Vps33B / 1281712
• VectorBaseID: AGAMI1_012979
• Length: 684
• Species: Anopheles gambiae
• Alignment Length: 689
• Identity: 270/689 - (39%)
• Similarity: 419/689 - (60%)
• Gaps: 56/689 - (8%)

  Fly     1 MDLTLDKKLQGFQLVAQEKLCSILCSIPGKKELILEPDLIKPLEHVVTASWLKLKGIQRIYKHDA 65
            ||....:||.||:.:|||||..:..|||.:|:||:||.||||||||..||||:.|||.:|:|.|:
Mosquito     1 MDSASGRKLLGFRQIAQEKLQHVFYSIPSEKDLIIEPALIKPLEHVCGASWLRKKGIDKIFKFDS 65

  Fly    66 AQSLPRSADQVHIYMIRSVLGTFQTLLKQLQPVASEEM----PDISMKMYHIVCVPSCYSYFQTL 126
            ....|:.  :..:|:|.|.|.||:::|.|:....|:..    |||..|.||::.:||..:.|:.|
Mosquito    66 KNPPPKR--KQFVYLITSSLLTFKSVLDQISGYQSQTSSMMEPDIRNKQYHVLVLPSVLASFEHL 128

  Fly   127 LEQAGLYGLVQLHHFNWDFIYFDQGVLSLELPNLYECLYLQKNTSPLPAVAQSLRLLQMICGQPS 191
            ||:.||:|:|:|::|.|||:..|:.:|||||||::..::::|:|:||.::|||:|:..::.|:|.
Mosquito   129 LEEEGLHGIVELYNFQWDFLLLDESLLSLELPNVFADVFVRKDTTPLGSIAQSIRIFNLVMGKPH 193

  Fly   192 LILSFGHHSSQLMQMAKTL---------------GKLPAPTNPPDYGGWLVIDRDKDYPASLLTP 241
            |:.|.|.::.:::.|...:               ||:..|...|:|...|::|||:||||.||||
Mosquito   194 LVFSLGENAEKILHMVHRMEAAKRPNVGGKENAAGKVDQPEKEPEYSAMLILDRDRDYPACLLTP 258

  Fly   242 AIYAGLLLEVFEHSSGEILVDNSKNKIRSQRVELLQGKKSKIGVNSASKPCSIRLNSTSDEIYGD 306
            .:|.|||||:...:||.:.||...|||::.::..|| :::....:...:..|:|::...|.||.:
Mosquito   259 VVYCGLLLEIQPLNSGSLAVDGEYNKIKNGKLAFLQ-EQNAAAASKQQETTSLRMSGAQDMIYLE 322

  Fly   307 NRYKRFAQVSSLIHAQVKALGLELQK-LNDMQLDEMHDYVARKLPKLTELKSKVLRHLNASEIVI 370
            :||:.|::|.||:.||.||||||.:. ..:|:|.||.:||..||||:...|.::.:||...|.::
Mosquito   323 HRYRHFSEVISLLSAQAKALGLEGKAYTREMKLHEMKEYVTHKLPKVAAAKKELFKHLRLCETIV 387

  Fly   371 QMMG-NFRKLQTLEEDILNNDSRKRLLSEIDELLTTDGQRFNTLRLLCLLHHCVGVAPEELQIFA 434
            :.:| ||.|.|.:||.||.|.:||::::.|.|||::|..|:|||||:||.|..:|:..|::....
Mosquito   388 EEIGANFEKHQMIEESILTNTNRKQIMNYILELLSSDAHRYNTLRLICLYHVTIGLTGEDMTRLM 452

  Fly   435 RNYCNLFGHQELGVFQQLSQAGLLPPLVVEKKAPTKLLSNLPLPKFQQTEFQANANRLKLL-TSS 498
            ..|.|.||::.|.:|..|.||.|.|......|  ||:||.:.:|.. :|.||..||:||.| |.:
Mosquito   453 TGYLNAFGYRHLSLFHSLFQARLFPDTTNLSK--TKILSQISIPTL-KTPFQIEANKLKQLPTDA 514

  Fly   499 GD----------GQDGGSSSKSQS-------SGLQTCPSFVFNGTYIPLVAQLCSILLKINSAEE 546
            .|          .:|||.:...||       :|.:||||:||||.|||||.||.:::...:|.:.
Mosquito   515 NDTATTATTPTTDRDGGLTGGVQSTGGGNVAAGGKTCPSYVFNGNYIPLVTQLTNLIFAASSFDN 579

  Fly   547 LSSKLGMIEGLHLHLDS-------GKITPKAYASQVKLNG----VADQDMFPLRLRNLFVFIVGG 600
            |:::||.:|.|.:...|       |..|..|..|..:|:.    ||...:.|.:.:.:|:|||||
Mosquito   580 LNTRLGHLERLKVSGRSLTASGQPGDHTQCAPRSIKELSASSHKVALNQLLPFKEKTMFIFIVGG 644

  Fly   601 ASYAEIAACDFVAKLTGAQITVASDSLMAGSDLIATAFN 639
            .:|||||||..:.:..||:|.::||.::||.|||.:..|
Mosquito   645 ITYAEIAACHLLERTIGAKIVLSSDRIIAGHDLIESVVN 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps33B	NP_651395.1	Sec1	31..634	CDD:460020	253/652 (39%)
Vps33B	XP_321664.4	None