Protein Alignment Vps33B and car

DIOPT Version :10

• Sequence 1: NP_651395.1
• Gene: Vps33B / 43077
• FlyBaseID: FBgn0039335
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_312907.4
• Gene: car / 1273876
• VectorBaseID: AGAMI1_009086
• Length: 605
• Species: Anopheles gambiae
• Alignment Length: 622
• Identity: 135/622 - (21%)
• Similarity: 259/622 - (41%)
• Gaps: 76/622 - (12%)

  Fly     9 LQGFQLVAQEKLCSILCSIPGKKELILEPDLIKPLEHVVTASWLKLKGIQRIYKHDAAQSLPRSA 73
            :|..|..|..:...||....|.|.:|.:..|..|:..|...::||        :|...:..|..:
Mosquito    16 VQLLQEAAVREFVKILDRCEGTKAIIWDESLGGPVGLVARYTFLK--------EHHVTKMYPLRS 72

  Fly    74 D---QVHIYMIRSVLGTFQTLLKQLQPVASEE--MPDISMKMYHIVCVPSCYSYFQTLLEQAGLY 133
            :   .:.:..|..:....|||:..:.....||  ...:|.|.|.:..:|......:..|:..|::
Mosquito    73 EAWTDIDVKNIIFITRPHQTLMDYIANNIHEEERKRKVSRKEYFLYFLPKKSFLCEKRLQIKGVH 137

  Fly   134 G-LVQLHHFNWDFIYFDQGVLSLELPNLYECLYLQKNTSPLPAVAQSLRLLQMICGQPSLILSFG 197
            | |..:..|..:|..||..:||:||.:.|:.:||:.:||.|...|.:|..||.:.|:...:...|
Mosquito   138 GSLSYIGEFRCEFFPFDNDLLSMELKDAYKEIYLEGDTSSLHQSACALVALQKLYGRIPKVYGIG 202

  Fly   198 HHSSQLMQMAKTLGKLPAPTNPPDYG---GWLVIDRDKDYPASLLTPAIYAGLLLEVFEHSSGEI 259
            .::.::.:|.|.|.:........:.|   ..:::||..|..:.|.|...|.||:.|:|.
Mosquito   203 GYAQRVWEMTKALTEEDGHVMNSEKGVIDQMIILDRSTDLMSVLATQLTYEGLIDEIFG------ 261

  Fly   260 LVDNSKNKIRSQRVELLQGKKSKIGVNSASKPCSIRLNSTSDEIYGDNRYKRFAQVSSLIHAQVK 324
             ::|:...:.:::....:|    :..:..::.....||| .:::|.:.|.|.|..|.:::....|
Mosquito   262 -INNTTVNLPAEKFNTGEG----LSTDRNTEKSQFILNS-KEQLYAELRDKNFNAVGAVLSRMAK 320

  Fly   325 ALGLEL-QKLNDMQLDEMHDYVARKLPKLTELKSKVLRHLNASEIVIQMMGNFRKLQTL---EED 385
            ::.... :...:..:.|:..:| ..||.:...:..:..|...:|:|..::.:...|..|   :|.
Mosquito   321 SIRSRANENHGEKSIQELKKFV-ESLPHIKSNEQSLATHTTIAELVQDVISSHAFLDVLGCEQEF 384

  Fly   386 ILNNDSRKRLLSEIDELLTTDGQRFNTLRLLCLLHHC-VGVAPEELQIFARNYCNLFGHQELGVF 449
            :|.:|..|. .|.|::::..:....:.|||:|:.... .|:.|:.|..:.|....::|.:.|...
Mosquito   385 LLCSDVDKP-NSFIEDMIAKEAPLRSVLRLICMQSIAGTGLKPKVLDYYKRELVQVYGLKTLLTL 448

  Fly   450 QQLSQAGLLPPLVVEKKAPTKLLSNLPLPKFQQTEFQANANRLKLLTSSGDGQDGGSSSKSQSSG 514
            ..|.:||||.                     |||..:......|.|..:.:..:
Mosquito   449 GNLEKAGLLR---------------------QQTGSRTYHVLRKTLNLTAETPE----------- 481

  Fly   515 LQTCPSFV--FNGTYIPLVAQLCSILLKINSAEELSSKLGMIEGLHLHLDSGKITPKAYASQVKL 577
             :..|..:  .:..|.||..::....||.|..:.|:.||..:.|  ...:..:.:|...:.:...
Mosquito   482 -EVSPKDITYVHSIYAPLSVRIIEQHLKPNGWQLLTEKLSSLPG--PTFEDFQASPSLSSRRGSF 543

  Fly   578 NGVADQDMFPLRLRNLFVFIVGGASYAEIAACDFVAK 614
            .....|...|   |.:.||.|||.::|||:|..|:|:
Mosquito   544 TSELSQSDIP---RVIVVFFVGGCTFAEISALRFLAQ 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps33B	NP_651395.1	Sec1	31..634	CDD:460020	129/600 (22%)
car	XP_312907.4	Sec1	38..601	CDD:460020	129/600 (22%)