DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alrm and RLP35

DIOPT Version :9

Sequence 1:	NP_651393.1	Gene:	alrm / 43074	FlyBaseID:	FBgn0039332	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001319521.1	Gene:	RLP35 / 820279	AraportID:	AT3G11080	Length:	943	Species:	Arabidopsis thaliana

Alignment Length:	363	Identity:	94/363 - (25%)
Similarity:	142/363 - (39%)	Gaps:	83/363 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 NSSIAKIPHLLFDTFPDLQVLRMENCSLETFEKPQFEGASNLMSLFLGYNR-LKDIPKNIFLGAD 137
            |||:.::        .:|:||.:....|:..........|:|.||.|.||: |..||.:|    :
plant   118 NSSLFRL--------QNLRVLDLTQNDLDGEIPSSIGNLSHLTSLHLSYNQFLGLIPSSI----E 170

  Fly   138 NLA---TLHLQGNQL-----KQLGNHSFHALKEVKELSLAENQLE-QI--SLGVFSGMRKLMDLN 191
            ||:   :|||..||.     ..:||     |..:..|.|:.||.. ||  |:|   .:..|..|:
plant   171 NLSRLTSLHLSSNQFSGQIPSSIGN-----LSHLTSLELSSNQFSGQIPSSIG---NLSNLTFLS 227

  Fly   192 LAGNR-LDALPRGVFDRNL-NLTKLNLARNRFTA-FESELLKL-QPVFTQLD---ISGNIFQELT 249
            |..|. ...:|..:  .|| .||.|.|:.|.|.. ..|....| |.:..|:|   :|||:...|
plant   228 LPSNDFFGQIPSSI--GNLARLTYLYLSYNNFVGEIPSSFGNLNQLIVLQVDSNKLSGNVPISL- 289

  Fly   250 LNFTMLDVAIAHSCDLRRLTVYGVIHELDLHNNSLREMP-HIPLAANVSSLDLSHNPLGNLQGNP 313
            ||.|.|...:..                  ||.....:| :|.|.:|:...:.|:|.......:.
plant   290 LNLTRLSALLLS------------------HNQFTGTIPNNISLLSNLMDFEASNNAFTGTLPSS 336

  Fly   314 LRRFTSLLRLNLSATGAH-ELPEGLFKKQSHLQMLDISGNSIYS---------LKITIFDSLKAL 368
            |.....|:||:||....: .|..|.....|:||.|.|..|:...         :.:|:||
plant   337 LFNIPPLIRLDLSDNQLNGTLHFGNISSPSNLQYLIIGSNNFIGTIPRSLSRFVNLTLFD----- 396

  Fly   369 QYFYFQQNNWNCDFLQLLMSSFVKRKD---ISFMEDIT 403
                ....|..|..:...:.|.:|..|   :|::...|
plant   397 ----LSHLNTQCRPVDFSIFSHLKSLDDLRLSYLTTTT 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	LRR_RI	84..354	CDD:238064	81/290 (28%)
		LRR_8	91..149	CDD:290566	21/61 (34%)
		leucine-rich repeat	91..114	CDD:275380	4/22 (18%)
		leucine-rich repeat	115..138	CDD:275380	10/23 (43%)
		LRR_8	138..197	CDD:290566	22/70 (31%)
		leucine-rich repeat	139..162	CDD:275380	9/30 (30%)
		leucine-rich repeat	163..186	CDD:275380	8/25 (32%)
		LRR_8	185..243	CDD:290566	19/64 (30%)
		leucine-rich repeat	187..210	CDD:275380	7/24 (29%)
		leucine-rich repeat	211..283	CDD:275380	21/76 (28%)
		leucine-rich repeat	284..319	CDD:275380	7/35 (20%)
		LRR_8	318..377	CDD:290566	16/68 (24%)
		leucine-rich repeat	320..343	CDD:275380	7/23 (30%)
		leucine-rich repeat	344..365	CDD:275380	8/29 (28%)
RLP35	NP_001319521.1	LRRNT_2	39..95	CDD:311940
		PLN00113	79..>658	CDD:331614	94/363 (26%)
		leucine-rich repeat	103..123	CDD:275380	3/4 (75%)
		leucine-rich repeat	127..150	CDD:275380	4/22 (18%)
		leucine-rich repeat	151..174	CDD:275380	12/26 (46%)
		leucine-rich repeat	175..198	CDD:275380	8/27 (30%)
		leucine-rich repeat	199..222	CDD:275380	8/25 (32%)
		leucine-rich repeat	223..246	CDD:275380	7/24 (29%)
		leucine-rich repeat	247..270	CDD:275380	8/22 (36%)
		leucine-rich repeat	271..294	CDD:275380	8/23 (35%)
		leucine-rich repeat	295..318	CDD:275380	6/40 (15%)
		leucine-rich repeat	319..337	CDD:275380	2/17 (12%)
		leucine-rich repeat	343..367	CDD:275380	7/23 (30%)
		leucine-rich repeat	368..388	CDD:275380	5/19 (26%)
		leucine-rich repeat	392..417	CDD:275380	6/33 (18%)
		leucine-rich repeat	443..469	CDD:275380
		leucine-rich repeat	470..492	CDD:275380
		leucine-rich repeat	493..516	CDD:275380
		leucine-rich repeat	517..541	CDD:275380
		leucine-rich repeat	542..570	CDD:275380
		leucine-rich repeat	571..594	CDD:275380
		leucine-rich repeat	596..617	CDD:275380
		leucine-rich repeat	618..641	CDD:275380
		LRR_8	640..698	CDD:316378
		leucine-rich repeat	642..665	CDD:275380
		leucine-rich repeat	716..803	CDD:275380
		PLN00113	<758..864	CDD:331614
		leucine-rich repeat	804..825	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000