DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alrm and RLP31

DIOPT Version :9

Sequence 1:	NP_651393.1	Gene:	alrm / 43074	FlyBaseID:	FBgn0039332	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_187188.2	Gene:	RLP31 / 819701	AraportID:	AT3G05370	Length:	860	Species:	Arabidopsis thaliana

Alignment Length:	473	Identity:	114/473 - (24%)
Similarity:	173/473 - (36%)	Gaps:	106/473 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LPPSYHLATPSSGSGQLRRLWLQDHCSAGICTNVVIGRSDYVILSQAPIGGTTMLTFL----NSS 76
            :|||.         |.|.||.:.|     :..|.::|:      ..|.||..|.|.:|    |..
plant   148 VPPSI---------GNLSRLTILD-----LWDNKLVGQ------LPASIGNLTQLEYLIFSHNKF 192

  Fly    77 IAKIPHLLFDTFPDLQVLRMENCSLETFEKPQFEGASNLMSLFLGYNRLK-DIPKNIFLGADNLA 140
            ...|| :.|.....|.|:.:.|.|.|:.......|..||....:|.|... .:||::|. ..:|.
plant   193 SGNIP-VTFSNLTKLLVVNLYNNSFESMLPLDMSGFQNLDYFNVGENSFSGTLPKSLFT-IPSLR 255

  Fly   141 TLHLQGNQLKQLGNHSFHALKEVKELSLAENQLEQISLGVFSGMRKLMDLNLAGNRLDALPRGVF 205
            ..:|:||..|  |...|.                    .::|...:|..|.|:.|:.|.......
plant   256 WANLEGNMFK--GPIEFR--------------------NMYSPSTRLQYLFLSQNKFDGPIPDTL 298

  Fly   206 DRNLNLTKLNLARNRFTAFESELLKLQPVFTQLDISGN------IFQELT-------LNFTM--L 255
            .:.|||.:|:|:.|..|......|...|...::::.||      .|..::       |||..  .
plant   299 SQYLNLIELDLSFNNLTGSFPTFLFTIPTLERVNLEGNHLKGPVEFGNMSSSSSLKFLNFAQNEF 363

  Fly   256 DVAIAHSCDLRRLTVYGVIHELDL-HNNSLREMPH-IPLAANVSSLDLSHNPLGNLQGNP---LR 315
            :.:|..|     ::.|..:.||.| .||.:..:|. |...|.:....|..|   |:.|..   |.
plant   364 NGSIPES-----VSQYLNLEELHLSFNNFIGTIPRSISKLAKLEYFCLEDN---NMVGEVPSWLW 420

  Fly   316 RFTSLLRLNLSATGAHELPEGLFKKQSHLQMLDISGNSIYSLKITIFDSLKALQYFYFQQNNWNC 380
            |.|.:...|.|.....|..|||  .::.:|.||:|.||...........|::|:......|.:|.
plant   421 RLTMVALSNNSFNSFGESSEGL--DETQVQWLDLSSNSFQGPFPHWICKLRSLEILIMSDNRFNG 483

  Fly   381 DFLQLLMSSFVKRKDISFMEDITAPELVDDYV---------------DGIACWYESDKQSKKCES 430
            .....|.|..|...|:....:..:..|.|.:|               ||:.     .|....|:
plant   484 SIPPCLSSFMVSLTDLILRNNSLSGPLPDIFVNATKLLSLDVSRNKLDGVL-----PKSLIHCK- 542

  Fly   431 GGSDAAMELSVVR-NEIK 447
                 ||:|..|| |:||
plant   543 -----AMQLLNVRSNKIK 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	LRR_RI	84..354	CDD:238064	71/290 (24%)
		LRR_8	91..149	CDD:290566	17/58 (29%)
		leucine-rich repeat	91..114	CDD:275380	6/22 (27%)
		leucine-rich repeat	115..138	CDD:275380	6/23 (26%)
		LRR_8	138..197	CDD:290566	12/58 (21%)
		leucine-rich repeat	139..162	CDD:275380	7/22 (32%)
		leucine-rich repeat	163..186	CDD:275380	1/22 (5%)
		LRR_8	185..243	CDD:290566	14/57 (25%)
		leucine-rich repeat	187..210	CDD:275380	5/22 (23%)
		leucine-rich repeat	211..283	CDD:275380	20/87 (23%)
		leucine-rich repeat	284..319	CDD:275380	9/38 (24%)
		LRR_8	318..377	CDD:290566	15/58 (26%)
		leucine-rich repeat	320..343	CDD:275380	6/22 (27%)
		leucine-rich repeat	344..365	CDD:275380	6/20 (30%)
RLP31	NP_187188.2	leucine-rich repeat	422..446	CDD:275380	7/25 (28%)
		leucine-rich repeat	447..470	CDD:275380	7/22 (32%)
		leucine-rich repeat	471..495	CDD:275380	5/23 (22%)
		leucine-rich repeat	496..519	CDD:275380	4/22 (18%)
		leucine-rich repeat	520..543	CDD:275380	4/33 (12%)
		leucine-rich repeat	544..565	CDD:275380	7/12 (58%)
		leucine-rich repeat	568..593	CDD:275380
		leucine-rich repeat	594..621	CDD:275380
		leucine-rich repeat	622..692	CDD:275380
		PLN00113	<681..758	CDD:331614
		leucine-rich repeat	693..716	CDD:275380
		leucine-rich repeat	717..738	CDD:275380
		LRRNT_2	33..78	CDD:311940
		PLN00113	60..>610	CDD:331614	114/473 (24%)
		leucine-rich repeat	86..109	CDD:275380
		leucine-rich repeat	110..133	CDD:275380
		leucine-rich repeat	134..157	CDD:275380	5/17 (29%)
		leucine-rich repeat	158..181	CDD:275380	7/33 (21%)
		leucine-rich repeat	182..205	CDD:275380	6/23 (26%)
		leucine-rich repeat	206..229	CDD:275380	6/22 (27%)
		leucine-rich repeat	230..253	CDD:275380	6/23 (26%)
		leucine-rich repeat	254..279	CDD:275380	8/46 (17%)
		leucine-rich repeat	280..303	CDD:275380	5/22 (23%)
		leucine-rich repeat	328..376	CDD:275380	9/52 (17%)
		leucine-rich repeat	377..398	CDD:275380	7/20 (35%)
		leucine-rich repeat	401..421	CDD:275380	5/22 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000