DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment alrm and RLP30

DIOPT Version :9

Sequence 1:	NP_651393.1	Gene:	alrm / 43074	FlyBaseID:	FBgn0039332	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_187187.1	Gene:	RLP30 / 819700	AraportID:	AT3G05360	Length:	786	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	123/557 - (22%)
Similarity:	201/557 - (36%)	Gaps:	170/557 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLSLQVV--LILPPSYHLATPSSGSGQLRRLWLQDHCSAGICTNVVIGRSDY-----VILSQAPI 64
            |..||.:  |.|...:.....:|..|.|.||...|..|..:...|:...|..     ::||:...
plant   107 LFKLQQLQNLTLSDCHLYGEVTSSLGNLSRLTHLDLSSNQLTGEVLASVSKLNQLRDLLLSENSF 171

  Fly    65 GGT-----TMLTFLNSSIAKIPHLLFDTF----PDLQVLRMENCSLETFEKPQFEGASNLMSLFL 120
            .|.     |.||.|:|..........:.|    |:|..|...|.:...|:       |.|.|...
plant   172 SGNIPTSFTNLTKLSSLDISSNQFTLENFSFILPNLTSLSSLNVASNHFK-------STLPSDMS 229

  Fly   121 GYNRLK--DIPKNIFLGA--------DNLATLHLQGNQLKQLGNHSFHALKEVKELSLAENQLEQ 175
            |.:.||  |:.:|.|:|.        .:|..::|:|||.                       :..
plant   230 GLHNLKYFDVRENSFVGTFPTSLFTIPSLQIVYLEGNQF-----------------------MGP 271

  Fly   176 ISLGVFSGMRKLMDLNLAGNRLDA-LPRGVFDRNLNLTKLNLARNRF-----TAFESELLKLQPV 234
            |..|..|...:|.|||||.|:.|. :|..:.:.: :|..|:|:.|..     |:. |:|:.||
plant   272 IKFGNISSSSRLWDLNLADNKFDGPIPEYISEIH-SLIVLDLSHNNLVGPIPTSI-SKLVNLQ-- 332

  Fly   235 FTQLDISGNIFQELTLN-------FTMLDVAIAHSCDLRRLTVYG----------VIHELDLHNN 282
              .|.:|.|     ||.       :.::.|.::|:    ....:|          .:.||||.:|
plant   333 --HLSLSNN-----TLEGEVPGCLWGLMTVTLSHN----SFNSFGKSSSGALDGESMQELDLGSN 386

  Fly   283 SL-REMPH-IPLAANVSSLDLSHNPLGN------------LQGNPLR-------------RFTSL 320
            || ...|| |.....:..||||:|....            |:|..||             ..:.|
plant   387 SLGGPFPHWICKQRFLKYLDLSNNLFNGSIPPCLKNSTYWLKGLVLRNNSFSGFLPDVFVNASML 451

  Fly   321 LRLNLSATGAH-ELPEGLFKKQSHLQMLDISGN-----------SIYSLKITIFDSLKALQYFYF 373
            |.|::|..... :||:.|. ..:.:::|::..|           |:.||::.|..|.......|:
plant   452 LSLDVSYNRLEGKLPKSLI-NCTGMELLNVGSNIIKDTFPSWLVSLPSLRVLILRSNAFYGSLYY 515

  Fly   374 QQNNWNCDFLQLLMSSFVKRKDIS---FMEDITA------PELVDDYVD------GIACWYESDK 423
            ...::....|:|:        |||   |...::.      .|:|...::      |...||..:|
plant   516 DHISFGFQHLRLI--------DISQNGFSGTLSPLYFSNWREMVTSVLEENGSNIGTEDWYMGEK 572

  Fly   424 QSKKCESGGSDAAMELSVVRNEIKTFTELVEKKFVKV 460
            ..:...|             |.:....:.||..|:::
plant   573 GPEFSHS-------------NSMTMIYKGVETDFLRI 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	LRR_RI	84..354	CDD:238064	78/345 (23%)
		LRR_8	91..149	CDD:290566	18/67 (27%)
		leucine-rich repeat	91..114	CDD:275380	4/22 (18%)
		leucine-rich repeat	115..138	CDD:275380	9/32 (28%)
		LRR_8	138..197	CDD:290566	15/58 (26%)
		leucine-rich repeat	139..162	CDD:275380	5/22 (23%)
		leucine-rich repeat	163..186	CDD:275380	3/22 (14%)
		LRR_8	185..243	CDD:290566	20/63 (32%)
		leucine-rich repeat	187..210	CDD:275380	9/23 (39%)
		leucine-rich repeat	211..283	CDD:275380	21/93 (23%)
		leucine-rich repeat	284..319	CDD:275380	13/61 (21%)
		LRR_8	318..377	CDD:290566	15/70 (21%)
		leucine-rich repeat	320..343	CDD:275380	7/23 (30%)
		leucine-rich repeat	344..365	CDD:275380	6/31 (19%)
RLP30	NP_187187.1	LRRNT_2	40..81	CDD:285463
		leucine-rich repeat	89..112	CDD:275380	2/4 (50%)
		LRR_RI	107..317	CDD:238064	59/240 (25%)
		leucine-rich repeat	113..136	CDD:275380	5/22 (23%)
		LRR_8	135..195	CDD:290566	14/59 (24%)
		leucine-rich repeat	137..160	CDD:275380	5/22 (23%)
		leucine-rich repeat	161..184	CDD:275380	5/22 (23%)
		leucine-rich repeat	185..209	CDD:275380	5/23 (22%)
		LRR_8	208..268	CDD:290566	17/66 (26%)
		leucine-rich repeat	210..233	CDD:275380	7/29 (24%)
		leucine-rich repeat	234..257	CDD:275380	6/22 (27%)
		leucine-rich repeat	258..306	CDD:275380	17/71 (24%)
		leucine-rich repeat	260..279	CDD:275380	6/41 (15%)
		leucine-rich repeat	307..330	CDD:275380	7/23 (30%)
		leucine-rich repeat	331..352	CDD:275380	7/29 (24%)
		leucine-rich repeat	378..401	CDD:275380	10/22 (45%)
		leucine-rich repeat	402..425	CDD:275380	5/22 (23%)
		leucine-rich repeat	427..450	CDD:275380	4/22 (18%)
		leucine-rich repeat	451..474	CDD:275380	7/23 (30%)
		leucine-rich repeat	475..498	CDD:275380	3/22 (14%)
		leucine-rich repeat	539..647	CDD:275380	11/71 (15%)
		leucine-rich repeat	555..623	CDD:275380	9/55 (16%)
		leucine-rich repeat	648..669	CDD:275380
		DUF3546	<758..>786	CDD:288886
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000