Protein Alignment alrm and 2mit

DIOPT Version :10

• Sequence 1: NP_651393.1
• Gene: alrm / 43074
• FlyBaseID: FBgn0039332
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001262529.1
• Gene: 2mit / 41616
• FlyBaseID: FBgn0260793
• Length: 1155
• Species: Drosophila melanogaster
• Alignment Length: 412
• Identity: 106/412 - (25%)
• Similarity: 159/412 - (38%)
• Gaps: 89/412 - (21%)

  Fly    87 TFPDLQVLRMENCSLETFEKPQFEGASNLMSLFLGYNRLKDIPKNIFLGADN-----LATLHLQG 146
            |..||...::|:.||:.|        :.|..|.||.|.|:.||.::   ||.     ..||.|..
  Fly   124 TAMDLSSNQLESLSLDNF--------NQLRQLDLGNNSLEVIPLSL---ADTNMSLPFVTLDLSC 177

  Fly   147 NQLKQLGNHSFHA--LKEVKELSLAENQLEQISLGVFSGMRKLMDLNLAGNRLDALPRGVFDRNL 209
            |:..|:.. ||.|  |.::|.|:||.|:|..||...|..:.:|..|.|:.|.:..:....|....
  Fly   178 NKFSQIST-SFFAQRLPQLKNLNLAHNELLNISRESFYNLLELQTLVLSHNNISDIDYETFLALP 241

  Fly   210 NLTKLNLARNRFTAFESELLKLQPVFTQLDIS-----GNIFQELTLNFTM--LDVAIAHSCDLRR 267
            ||..|:|:.||.:......|:..|....|.|:     |...||...::::  ||.:....|.:..
  Fly   242 NLQYLDLSHNRLSGSAIRALQGIPDLVSLSIAYNPDVGVAMQEFVASWSLKELDASGTGLCQVPA 306

  Fly   268 LTVYGVIHELDLHNNSLR-----EMPHIPLAANVSSLDLSHNPLGNLQGNPLRRF---------- 317
            .....| ..|.|.:|.|:     :|...||   :..|||||:.:..::.:.|.|.
  Fly   307 ALAQSV-RTLKLSDNWLKAINCGDMDSYPL---LQYLDLSHSRIAQVEDDALGRLELLESLFLDR 367

  Fly   318 -----------TSLLRLNLSATGAHELPEGLFKKQSHLQMLDISGNSIYSLKITIFDSLKALQYF 371
                       .||..|.|......|||...|....:||.||:|.|.:..|.......|..|.
  Fly   368 NLLMRVPSSLPPSLEHLFLQHNQIMELPPQAFVGLVNLQTLDLSNNRLIFLPPLSLPKLLTLN-- 430

  Fly   372 YFQQNNWNCDFLQLLMSSFVKRKDISFMEDITAPELVDDYVD----------GIACWYESDKQSK 426
                          |.||.|:....|.:.  |.|:|.|..::          |||.|....:...
  Fly   431 --------------LESSGVESVSQSIVH--TLPQLRDLLLEDNPIKCSDLLGIAEWASPCRSVD 479

  Fly   427 KCESGGSDAAMELSVVRNEIKT 448
            ..:|.|:..:     .|.::||
  Fly   480 AGQSNGASVS-----GRVDLKT 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	leucine-rich repeat	91..114	CDD:275380	5/22 (23%)
		LRR	<100..426	CDD:443914	97/375 (26%)
		leucine-rich repeat	115..138	CDD:275380	9/22 (41%)
		leucine-rich repeat	139..162	CDD:275380	9/24 (38%)
		leucine-rich repeat	163..186	CDD:275380	9/22 (41%)
		leucine-rich repeat	187..210	CDD:275380	5/22 (23%)
		leucine-rich repeat	211..283	CDD:275380	18/78 (23%)
		leucine-rich repeat	284..319	CDD:275380	11/60 (18%)
		leucine-rich repeat	320..343	CDD:275380	7/22 (32%)
		leucine-rich repeat	344..365	CDD:275380	7/20 (35%)
2mit	NP_001262529.1	LRR	<106..458	CDD:443914	97/367 (26%)
		leucine-rich repeat	124..143	CDD:275380	7/26 (27%)
		leucine-rich repeat	144..167	CDD:275380	10/25 (40%)
		leucine-rich repeat	172..194	CDD:275380	9/22 (41%)
		leucine-rich repeat	195..218	CDD:275380	9/22 (41%)
		leucine-rich repeat	219..242	CDD:275380	5/22 (23%)
		leucine-rich repeat	243..311	CDD:275380	15/67 (22%)
		leucine-rich repeat	312..335	CDD:275380	6/23 (26%)
		leucine-rich repeat	336..359	CDD:275380	7/22 (32%)
		leucine-rich repeat	360..380	CDD:275380	0/19 (0%)
		leucine-rich repeat	381..404	CDD:275380	7/22 (32%)
		leucine-rich repeat	405..449	CDD:275380	15/61 (25%)