Protein Alignment alrm and atk

DIOPT Version :10

• Sequence 1: NP_651393.1
• Gene: alrm / 43074
• FlyBaseID: FBgn0039332
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_649228.1
• Gene: atk / 40266
• FlyBaseID: FBgn0036995
• Length: 1535
• Species: Drosophila melanogaster
• Alignment Length: 424
• Identity: 105/424 - (24%)
• Similarity: 171/424 - (40%)
• Gaps: 97/424 - (22%)

  Fly    73 LNSSIAKIPHLLFDTFPDLQVLRMENCSLETFEKPQFEGAS-------NLMSLFLGYNRLKDIPK 130
            |.|.||.:|.:            :|..||:..:......|:       ||..|.|..||::.:|:
  Fly   514 LKSVIAGLPRI------------VERISLKGNQITSLPAAASKDLQLPNLRMLDLSQNRIEQLPR 566

  Fly   131 NIFLGADNLATLHLQGNQLKQLGNHSFHALKEVKELSLAENQLEQISLGVFSGMRKLMDLNLAGN 195
            :.|.||..|..|.|..|:|:||.:.||..::.::.|.|.||||.:........:.:|.:|||..|
  Fly   567 HGFQGAMELRVLSLAQNELRQLKDTSFIGIQRLELLHLQENQLGEADERALLPLAELRNLNLQSN 631

  Fly   196 RLDALPRGVFDRNLNLTKLNLARNRFTAFESELLKLQPVFTQLDISGNIFQELTLNFTMLDVAIA 260
            :|:|:....|..|..|.:|:|:||...:........|.....||:|||         .:||:::.
  Fly   632 KLEAITDNFFSNNSRLEQLDLSRNLIRSISPTAFDTQRSLEYLDLSGN---------ALLDISVG 687

  Fly   261 HSCDLRRLTVYGVIHELDLHN-NSLREMPHIPLAANVSSLDLSHNPLGNLQGNPLRRFTSLLRLN 324
                              |.| |:||:            :|||:|.:..:|.:.:..:.:::.:.
  Fly   688 ------------------LGNLNNLRD------------IDLSYNQISRIQSDVIGGWRNVVEIR 722

  Fly   325 LSATGAHELPEGLFKKQSHLQMLDISGNSIYSLKITIFDSLKALQYFYFQQNNWNCDFLQLLMSS 389
            ||.....||.:|.|:....||.||:|.|.|.:::......|..||.|....|            .
  Fly   723 LSNNLIVELQQGTFRNLPKLQYLDLSSNEIRNVEPGALKGLDELQEFVLADN------------K 775

  Fly   390 FVKRKDISFMEDITAPELVDDY----------------VDGIACWYESDKQSKKCESGGSDAAME 438
            .|:.||..|.|   .|.|:..:                .:.:.....|:...:..|:.|..:...
  Fly   776 LVELKDHVFEE---LPSLLASHFQYNKLRYISPESFHNANSLVFLNLSNNHFRNMENIGLRSMRN 837

  Fly   439 LSVV---RNEIKTFTELVEKKFVKVYRMLEEMKM 469
            |.|:   .|.:|    ||....:|....|.|:||
  Fly   838 LEVLDLSTNGVK----LVSTMPLKALNWLVELKM 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	leucine-rich repeat	91..114	CDD:275380	4/29 (14%)
		LRR	<100..426	CDD:443914	86/349 (25%)
		leucine-rich repeat	115..138	CDD:275380	9/22 (41%)
		leucine-rich repeat	139..162	CDD:275380	9/22 (41%)
		leucine-rich repeat	163..186	CDD:275380	6/22 (27%)
		leucine-rich repeat	187..210	CDD:275380	9/22 (41%)
		leucine-rich repeat	211..283	CDD:275380	15/72 (21%)
		leucine-rich repeat	284..319	CDD:275380	7/34 (21%)
		leucine-rich repeat	320..343	CDD:275380	6/22 (27%)
		leucine-rich repeat	344..365	CDD:275380	7/20 (35%)
atk	NP_649228.1	leucine-rich repeat	886..906	CDD:275380
		PCC	891..>936	CDD:188093
		leucine-rich repeat	69..89	CDD:275380
		leucine-rich repeat	90..113	CDD:275380
		LRR	93..530	CDD:443914	6/27 (22%)
		leucine-rich repeat	115..138	CDD:275380
		leucine-rich repeat	139..160	CDD:275380
		leucine-rich repeat	161..184	CDD:275380
		leucine-rich repeat	185..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380
		leucine-rich repeat	234..259	CDD:275380
		leucine-rich repeat	260..283	CDD:275380
		leucine-rich repeat	284..307	CDD:275380
		leucine-rich repeat	308..359	CDD:275380
		leucine-rich repeat	334..348	CDD:275378
		PLN00113	359..>824	CDD:215061	92/375 (25%)
		leucine-rich repeat	360..383	CDD:275380
		leucine-rich repeat	384..407	CDD:275380
		leucine-rich repeat	408..431	CDD:275380
		leucine-rich repeat	432..455	CDD:275380
		leucine-rich repeat	456..476	CDD:275380
		leucine-rich repeat	480..501	CDD:275380
		leucine-rich repeat	505..517	CDD:275378	1/2 (50%)
		leucine-rich repeat	525..550	CDD:275380	4/24 (17%)
		leucine-rich repeat	551..574	CDD:275380	9/22 (41%)
		leucine-rich repeat	575..598	CDD:275380	9/22 (41%)
		leucine-rich repeat	599..622	CDD:275380	6/22 (27%)
		leucine-rich repeat	623..646	CDD:275380	9/22 (41%)
		leucine-rich repeat	647..670	CDD:275380	6/22 (27%)
		leucine-rich repeat	671..693	CDD:275380	9/48 (19%)
		leucine-rich repeat	694..717	CDD:275380	7/34 (21%)
		leucine-rich repeat	718..741	CDD:275380	6/22 (27%)
		leucine-rich repeat	742..763	CDD:275380	7/20 (35%)
		leucine-rich repeat	766..789	CDD:275380	9/37 (24%)
		leucine-rich repeat	790..813	CDD:275380	1/22 (5%)
		leucine-rich repeat	814..835	CDD:275380	3/20 (15%)
		leucine-rich repeat	838..861	CDD:275380	7/26 (27%)
		leucine-rich repeat	862..885	CDD:275380	4/6 (67%)