Protein Alignment alrm and Con

DIOPT Version :10

• Sequence 1: NP_651393.1
• Gene: alrm / 43074
• FlyBaseID: FBgn0039332
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Alignment Length: 443
• Identity: 93/443 - (20%)
• Similarity: 162/443 - (36%)
• Gaps: 110/443 - (24%)

  Fly    74 NSSIAKIPHLLFDTFPDLQVLRMENCSLETFEKPQFEGASNLMSLFLGYNRLKDIPKNIFLGADN 138
            |:.:..||.::.:...:|..:.:|...:|..:...|.....|..:.|..|.:..:.::.|.....
  Fly   168 NARLDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMALDQDAFANHIR 232

  Fly   139 LATLHLQGNQLKQLGNHSFHALKEVKELSLAENQLEQISLGVFSGMRKLMDLNLAGNRLDALPRG 203
            |..|:|:.||:.::..::|..|...:.|.|..|.:..:..|:|:.|.:|..||||.|:::.|...
  Fly   233 LRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSE 297

  Fly   204 VFDRNLNLTKLNLARNRF-----TAFESELLKLQPVFTQLDISGNIFQELTLNFTMLDVAIAHSC 263
            :|....||..|.|.||..     |.| :||..|    ::|::..|..:.::
  Fly   298 IFRGLGNLNVLKLTRNNLNFIGDTVF-AELWSL----SELELDDNRIERIS-------------- 343

  Fly   264 DLRRLTVYGVIHELDLHNNSLREMPHIPLAANVSSLDLSHNPLGNLQGNPLRRFTSLLRLNLSAT 328
             .|.|.....:..|:|.||.|:::.:                 |.|:|.|     :||.:|:.|.
  Fly   344 -ERALDGLNTLKTLNLRNNLLKKIDN-----------------GLLRGTP-----ALLSINVQAN 385

  Fly   329 GAHELP--------EGLFKKQSHLQMLDISGNS---------IYSLK-----ITIFDSLKALQYF 371
            ....|.        :.|....|.|.   :|.|.         |:.||     :.:.|||:.|
  Fly   386 KLETLTFYTFQPIMDNLVNSTSELL---VSDNKFICDCRLQWIFELKNRTRHLQLRDSLEDL--- 444

  Fly   372 YFQQNNWNCDFLQLLMSSFVKRKDISFMEDITAPELVDDYVDG-------------------IAC 417
                   :|...:..:|.||         |...|.::|....|                   :..
  Fly   445 -------HCTLQEPKLSHFV---------DPVPPTILDVLNIGGFTAIGSNSASMGGVGNSVVGS 493

  Fly   418 WYESDKQSKKCESGGSDAAMELSVVRNEIKTFTELVEKKFVKVYRMLEEMKMK 470
            .|.........:..||.:...|...|....:...:||.|..:..:..||:|.|
  Fly   494 SYSGLTMDDSRKHLGSRSRQALRGQRQFASSAENVVESKMRRRRKRQEEVKEK 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	leucine-rich repeat	91..114	CDD:275380	4/22 (18%)
		LRR	<100..426	CDD:443914	77/371 (21%)
		leucine-rich repeat	115..138	CDD:275380	4/22 (18%)
		leucine-rich repeat	139..162	CDD:275380	7/22 (32%)
		leucine-rich repeat	163..186	CDD:275380	6/22 (27%)
		leucine-rich repeat	187..210	CDD:275380	8/22 (36%)
		leucine-rich repeat	211..283	CDD:275380	17/76 (22%)
		leucine-rich repeat	284..319	CDD:275380	5/34 (15%)
		leucine-rich repeat	320..343	CDD:275380	6/30 (20%)
		leucine-rich repeat	344..365	CDD:275380	7/34 (21%)
Con	NP_523930.3	LRR	<157..459	CDD:443914	77/354 (22%)
		leucine-rich repeat	185..208	CDD:275380	4/22 (18%)
		leucine-rich repeat	209..232	CDD:275380	4/22 (18%)
		leucine-rich repeat	233..256	CDD:275380	7/22 (32%)
		leucine-rich repeat	257..280	CDD:275380	6/22 (27%)
		leucine-rich repeat	281..304	CDD:275380	8/22 (36%)
		leucine-rich repeat	305..328	CDD:275380	9/23 (39%)
		leucine-rich repeat	329..352	CDD:275380	5/41 (12%)
		leucine-rich repeat	353..376	CDD:275380	9/44 (20%)