Protein Alignment alrm and CG8852

DIOPT Version :10

• Sequence 1: NP_651393.1
• Gene: alrm / 43074
• FlyBaseID: FBgn0039332
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_608790.2
• Gene: CG8852 / 33577
• FlyBaseID: FBgn0031548
• Length: 663
• Species: Drosophila melanogaster
• Alignment Length: 446
• Identity: 101/446 - (22%)
• Similarity: 165/446 - (36%)
• Gaps: 137/446 - (30%)

  Fly    82 HLLFDTF--PDLQVLR-----MENC-SLETFEKPQFEGAS------------NLMSLFLGYNRLK 126
            |:..|.|  |.|.:..     ::|| .||:.|..:|.|.:            ||.::...||.|.
  Fly    96 HVSLDGFQTPPLGISSYGLEYLDNCVDLESVEIQRFVGDATLKLSCGGALIPNLTAVSFRYNELG 160

  Fly   127 DIPKNIFLGADNLATLHLQGNQLKQLGNHSFHALKEVKELSLAENQLEQISLGVFSGMRKLMDLN 191
            .:.........:|..||||.|.|:.|.....|:  :::||.:.:.:                ||.
  Fly   161 TLSGETIQDLPHLKILHLQQNSLRYLEYFKEHS--DLEELLIQDER----------------DLV 207

  Fly   192 LAGNR-LDALPRGVFDRNLNLTKLNLARNRFTAFESELLKLQPV-FTQLDISGNIFQELTLNFT- 253
            |..|. |:.||        .|.:|:| || ....|.:.|::.|. .|.|.|.....|...|..|
  Fly   208 LRFNEILNQLP--------ELRRLSL-RN-VEKIEDQFLRILPENLTDLIIENTPIQPGVLYLTE 262

  Fly   254 ----MLDVAIAHSCDLRRLTVYGVIHELD-----LHNNSLREMPHIPLAANVS---------SLD 300
                :::|.|. :|.|:...:... |.||     |..|::..:       |:|         :||
  Fly   263 GVAKLVNVTIT-NCQLKGFALQPA-HNLDIMYLNLSGNAISSL-------NISFESGPSTLLTLD 318

  Fly   301 LSHNPLGNLQGNPLRRFTSLLRLNLSATGAHELPEGLFK----KQSHLQMLDISGNSIYS----- 356
            ||.|.|.:|......|.|||..|:|.....|.|  .||:    ..:.:..:|:..|.:.|
  Fly   319 LSRNRLEHLNFTWFYRTTSLRSLHLQENHFHSL--SLFQLGFISSASIHHIDLRSNELMSFRDTE 381

  Fly   357 ----------LKITIFDSLKALQYFYFQQNNWNCDFL-------QLLMSSFVKRKDISFMEDITA 404
                      |:|:|.|            |.|:|.::       ..|...|...|.||.:.
  Fly   382 NADLPSWNPQLRISIDD------------NPWSCQWMLNFSHMQPQLFRLFQYSKYISHIN---- 430

  Fly   405 PELVDDYVDGIACWYE---SDKQSK-----KCESGGSDAAMELSVVRNEIKTFTEL 452
                   ::|::|..:   |::..|     .....|:|:::.:......:.:||.|
  Fly   431 -------INGLSCTPQEPPSEEPPKVRRIMHVRINGTDSSIPVPHPHGNVSSFTVL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	leucine-rich repeat	91..114	CDD:275380	8/40 (20%)
		LRR	<100..426	CDD:443914	88/387 (23%)
		leucine-rich repeat	115..138	CDD:275380	4/22 (18%)
		leucine-rich repeat	139..162	CDD:275380	9/22 (41%)
		leucine-rich repeat	163..186	CDD:275380	2/22 (9%)
		leucine-rich repeat	187..210	CDD:275380	7/23 (30%)
		leucine-rich repeat	211..283	CDD:275380	22/82 (27%)
		leucine-rich repeat	284..319	CDD:275380	10/43 (23%)
		leucine-rich repeat	320..343	CDD:275380	7/26 (27%)
		leucine-rich repeat	344..365	CDD:275380	7/35 (20%)
CG8852	NP_608790.2	LRR	<122..452	CDD:443914	89/391 (23%)
		leucine-rich repeat	149..172	CDD:275380	4/22 (18%)
		leucine-rich repeat	173..194	CDD:275380	9/22 (41%)
		leucine-rich repeat	220..242	CDD:275380	8/23 (35%)
		leucine-rich repeat	243..266	CDD:275380	6/22 (27%)
		leucine-rich repeat	267..287	CDD:275380	4/21 (19%)
		leucine-rich repeat	288..313	CDD:275380	6/31 (19%)
		leucine-rich repeat	314..337	CDD:275380	8/22 (36%)
		leucine-rich repeat	364..387	CDD:275378	3/22 (14%)
		leucine-rich repeat	392..403	CDD:275378	6/22 (27%)