Protein Alignment alrm and Nrros

DIOPT Version :9

• Sequence 1: NP_651393.1
• Gene: alrm / 43074
• FlyBaseID: FBgn0039332
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001334110.1
• Gene: Nrros / 224109
• MGIID: 2445095
• Length: 693
• Species: Mus musculus
• Alignment Length: 508
• Identity: 124/508 - (24%)
• Similarity: 174/508 - (34%)
• Gaps: 181/508 - (35%)

  Fly    35 LWLQDHCSAGICTNVVIGRSDYVILSQAPIGGTTM-----------LTFLNSSIAKIPH---LLF 85
            |||   | .|....:|..||.....:.|..||..:           |..:.||:.  ||   |:.
Mouse     6 LWL---C-LGFHFLIVEWRSGPGTATAASQGGCKVVDGVADCRGLNLASVPSSLP--PHSRMLIL 64

  Fly    86 D-------------TFPDLQVLRMENCSLETFEKPQFEGASNLMSLFLGYNRLKDIPK------N 131
            |             .:|.|:.|.:.:|.|:......|....:|.:|.|..|||.:..|      :
Mouse    65 DANPLKDLWNHSLQAYPRLENLSLHSCHLDRISHYAFREQGHLRNLVLADNRLSENYKESAAALH 129

  Fly   132 IFLGADNLATLHLQGNQL-KQLGNHSFHALKEVKELSLAENQLEQISLGVFSGMRKLMDLNLAGN 195
            ..||   |..|.|.||.| :.:.......|..::.:|||.|.|.::...:|.|:..|::|:|..|
Mouse   130 TLLG---LRRLDLSGNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSIFEGLEHLVELDLQRN 191

  Fly   196 RLDALPRGVFDRNLNLTKLNLARN-------------RF-----------------TAFESELLK 230
            .:..:..|.||....|.:||||.|             ||                 .|||.|:|.
Mouse   192 YIFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEVAFELEILD 256

  Fly   231 LQ-------PVFTQ------LDISGNIF------------QELTLNFTMLDVAIAH--------- 261
            |.       |:..|      |.:..|..            ||:...|.::|..:.:
Mouse   257 LSHNQLLFFPLLPQCGKLHTLLLQDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEE 321

  Fly   262 --SCDLRRLTVYGVIHELDLHNNSLREMP-----------HIPLAAN---------------VSS 298
              |.||..|..      ||:..|..|.:|           |:.|..|               ::.
Mouse   322 FSSSDLSALRF------LDMSQNQFRHLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPPGALTE 380

  Fly   299 LDLSHNPLGNLQGNPLRRFTSLLR----LNLSATGAHELPEGLFKKQSHLQMLDISGNSIY---- 355
            ||||||.|..|...|  ..|..||    .|||:.....:|.|||...|.:..:|:|.|.|.
Mouse   381 LDLSHNQLAELHLAP--GLTGSLRNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHNQISLCPQ 443

  Fly   356 -------------------SLKITIFD--SLKALQYFYFQ---------QNNW 378
                               ||:....|  .|||||...||         .:||
Mouse   444 MVPVDWEGPPSCVDFRNMGSLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNW 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	LRR_RI	84..354	CDD:238064	94/385 (24%)
		LRR_8	91..149	CDD:290566	19/63 (30%)
		leucine-rich repeat	91..114	CDD:275380	5/22 (23%)
		leucine-rich repeat	115..138	CDD:275380	9/28 (32%)
		LRR_8	138..197	CDD:290566	18/59 (31%)
		leucine-rich repeat	139..162	CDD:275380	7/23 (30%)
		leucine-rich repeat	163..186	CDD:275380	7/22 (32%)
		LRR_8	185..243	CDD:290566	24/100 (24%)
		leucine-rich repeat	187..210	CDD:275380	7/22 (32%)
		leucine-rich repeat	211..283	CDD:275380	28/137 (20%)
		leucine-rich repeat	284..319	CDD:275380	14/60 (23%)
		LRR_8	318..377	CDD:290566	25/96 (26%)
		leucine-rich repeat	320..343	CDD:275380	9/26 (35%)
		leucine-rich repeat	344..365	CDD:275380	7/45 (16%)
Nrros	NP_001334110.1	LRR 1. /evidence=ECO:0000255	58..79		3/20 (15%)
		PLN00113	60..>439	CDD:215061	95/389 (24%)
		leucine-rich repeat	60..82	CDD:275380	2/21 (10%)
		LRR 2. /evidence=ECO:0000255	82..103		5/20 (25%)
		leucine-rich repeat	83..106	CDD:275380	5/22 (23%)
		LRR 3. /evidence=ECO:0000255	106..127		7/20 (35%)
		leucine-rich repeat	107..133	CDD:275380	7/25 (28%)
		LRR 4. /evidence=ECO:0000255	133..155		7/24 (29%)
		leucine-rich repeat	134..158	CDD:275380	7/23 (30%)
		LRR_8	157..217	CDD:404697	20/59 (34%)
		LRR 5. /evidence=ECO:0000255	158..179		6/20 (30%)
		leucine-rich repeat	159..182	CDD:275380	7/22 (32%)
		LRR 6. /evidence=ECO:0000255	182..203		6/20 (30%)
		leucine-rich repeat	183..206	CDD:275380	7/22 (32%)
		LRR 7. /evidence=ECO:0000255	206..227		6/20 (30%)
		leucine-rich repeat	207..251	CDD:275380	9/43 (21%)
		LRR 8. /evidence=ECO:0000255	228..239		2/10 (20%)
		leucine-rich repeat	230..249	CDD:275380	1/18 (6%)
		LRR 9. /evidence=ECO:0000255	251..272		6/20 (30%)
		leucine-rich repeat	252..273	CDD:275380	5/20 (25%)
		LRR 10. /evidence=ECO:0000255	273..294		2/20 (10%)
		leucine-rich repeat	274..329	CDD:275380	9/54 (17%)
		PLN00113	309..>638	CDD:215061	48/196 (24%)
		LRR 11. /evidence=ECO:0000255	329..350		6/26 (23%)
		leucine-rich repeat	330..353	CDD:275380	6/28 (21%)
		LRR 12. /evidence=ECO:0000255	353..374		3/20 (15%)
		leucine-rich repeat	354..377	CDD:275380	3/22 (14%)
		LRR 13. /evidence=ECO:0000255	377..398		9/22 (41%)
		leucine-rich repeat	378..403	CDD:275380	11/26 (42%)
		LRR 14. /evidence=ECO:0000255	403..424		7/20 (35%)
		leucine-rich repeat	404..427	CDD:275380	7/22 (32%)
		LRR 15. /evidence=ECO:0000255	427..448		4/20 (20%)
		leucine-rich repeat	428..463	CDD:275380	4/34 (12%)
		LRR 16. /evidence=ECO:0000255	463..484		9/20 (45%)
		leucine-rich repeat	464..486	CDD:275380	9/21 (43%)
		LRR 17. /evidence=ECO:0000255	486..507		2/11 (18%)
		leucine-rich repeat	487..512	CDD:275380	2/10 (20%)
		LRR 18. /evidence=ECO:0000255	512..533
		leucine-rich repeat	513..537	CDD:275380
		LRR 19. /evidence=ECO:0000255	537..558
		leucine-rich repeat	538..559	CDD:275380
		LRR 20. /evidence=ECO:0000255	559..580
		LRR 21. /evidence=ECO:0000255	585..605

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45617
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100