Protein Alignment alrm and dma-1

DIOPT Version :9

• Sequence 1: NP_651393.1
• Gene: alrm / 43074
• FlyBaseID: FBgn0039332
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_492253.1
• Gene: dma-1 / 187968
• WormBaseID: WBGene00011345
• Length: 603
• Species: Caenorhabditis elegans
• Alignment Length: 433
• Identity: 104/433 - (24%)
• Similarity: 174/433 - (40%)
• Gaps: 81/433 - (18%)

  Fly     8 LSLQVVLILPPSYHLATPSSGSGQLRRLWLQDHCSAGICTNVVIGRSDYVILSQAPIGGTTMLTF 72
            |:|:.:.|.|||..:     ||.:||  |           |..|.|          .....:|..
 Worm    60 LTLRSLHIQPPSNRI-----GSNKLR--W-----------NDNINR----------FAQLRVLRL 96

  Fly    73 LNSSIAKIPHLLFDTFPDLQVLRMENCSLETFEKPQFEGASNLMSLFLGYNRLKDIPKNIFLGAD 137
            :|..|..:...:  ..|.|:||.:.:.::|......|.|...|..|.|..|.|..:|..:|....
 Worm    97 INCQIPAMSRSI--RLPSLEVLDLHSNNIEHATMSNFGGMPKLRVLDLSSNHLNILPTGVFTYLR 159

  Fly   138 NLATLHLQGNQLKQLGNHSFHALKEVKELSLAEN--QLEQISLGVFSGMRKLMDLNLAGNRLDAL 200
            .|.:|.|..|.:..|..:....|..::.|.|..|  .:|.|: .:|:.:.:|.:|.|....|.::
 Worm   160 ALRSLSLSNNTISDLSTNLLRGLNSLRVLRLDRNPIPIEHIN-ELFTDVSQLDELYLNHCNLSSI 223

  Fly   201 PRGVFDRNLNLTKLNLARNRFTAFESELLKLQPVFTQLDISGNIFQELT------LNFTMLDVAI 259
            .....||...|.:|.:..|......::.|:..|..:.||:|.|..||:|      .|.:.||  :
 Worm   224 YSLALDRIPQLRQLGIGGNNLKMVPTKELRSLPQLSVLDLSHNSIQEITACAFCNTNISKLD--L 286

  Fly   260 AHSCDLRRLTVYGVIHELDLHNNSLREMP--HIPLAAN----------------VSSLDLSHNPL 306
            :|:       :.|:..:...:.::.|.||  |:.|:.|                ::|:.||.|.|
 Worm   287 SHN-------LLGISKDSPFNEDAFRTMPLRHLDLSFNHMNDFDSKWLGWAQEELTSIALSGNFL 344

  Fly   307 GNLQGNPLRRFTSLLRLNLSATGAHELPEGLFKKQSHLQMLDISGNSIYSLKITIFDSLKALQYF 371
            .|.:.:......||:.|.|:......:|..|..:..||..|:||||.:..|...|...|..::.|
 Worm   345 KNFEESWTYTLKSLIHLELAYNHIKFIPVQLPSRYYHLISLNISGNELTYLPDNINTLLPNVKTF 409

  Fly   372 YFQQNNWNCDFLQLLMSSFVKRKDISFMEDITAPELVDDYVDG 414
            ....|.::.          ....|::|:.::   |.|  ||||
 Worm   410 DITANRFHT----------FSHTDLAFLNNV---EQV--YVDG 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	LRR_RI	84..354	CDD:238064	74/295 (25%)
		LRR_8	91..149	CDD:290566	17/57 (30%)
		leucine-rich repeat	91..114	CDD:275380	6/22 (27%)
		leucine-rich repeat	115..138	CDD:275380	7/22 (32%)
		LRR_8	138..197	CDD:290566	15/60 (25%)
		leucine-rich repeat	139..162	CDD:275380	6/22 (27%)
		leucine-rich repeat	163..186	CDD:275380	6/24 (25%)
		LRR_8	185..243	CDD:290566	14/57 (25%)
		leucine-rich repeat	187..210	CDD:275380	6/22 (27%)
		leucine-rich repeat	211..283	CDD:275380	17/77 (22%)
		leucine-rich repeat	284..319	CDD:275380	12/52 (23%)
		LRR_8	318..377	CDD:290566	17/58 (29%)
		leucine-rich repeat	320..343	CDD:275380	5/22 (23%)
		leucine-rich repeat	344..365	CDD:275380	8/20 (40%)
dma-1	NP_492253.1	LRR_8	90..147	CDD:338972	14/58 (24%)
		leucine-rich repeat	91..112	CDD:275380	3/22 (14%)
		leucine-rich repeat	113..136	CDD:275380	6/22 (27%)
		LRR	136..430	CDD:227223	74/313 (24%)
		leucine-rich repeat	137..160	CDD:275380	7/22 (32%)
		leucine-rich repeat	161..184	CDD:275380	6/22 (27%)
		leucine-rich repeat	185..209	CDD:275380	6/24 (25%)
		leucine-rich repeat	210..233	CDD:275380	6/22 (27%)
		leucine-rich repeat	234..257	CDD:275380	4/22 (18%)
		leucine-rich repeat	258..280	CDD:275380	7/21 (33%)
		leucine-rich repeat	281..307	CDD:275380	5/34 (15%)
		leucine-rich repeat	309..357	CDD:275380	9/47 (19%)
		leucine-rich repeat	382..405	CDD:275380	9/22 (41%)
		leucine-rich repeat	406..429	CDD:275380	4/32 (13%)
		TPKR_C2	438..>478	CDD:387596	104/433 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45617
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100