Protein Alignment alrm and lron-1

DIOPT Version :9

• Sequence 1: NP_651393.1
• Gene: alrm / 43074
• FlyBaseID: FBgn0039332
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_510424.4
• Gene: lron-1 / 181553
• WormBaseID: WBGene00008093
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 493
• Identity: 105/493 - (21%)
• Similarity: 178/493 - (36%)
• Gaps: 141/493 - (28%)

  Fly    31 QLRRLWLQDHCSAGICTNVVIGRSDYVILSQAPIGGTTM----------------LTFLNSSIAK 79
            |...|.||:.|:   ||:     :.|..:|....||:::                ||..|:.|.|
 Worm    17 QCPTLQLQEPCT---CTS-----TRYEAVSINCDGGSSLDAVLESLSNSPQAIDSLTISNTPIEK 73

  Fly    80 IPHLLFDTFPDLQVLRMENCSLETFEKPQFEG--------------------------------- 111
            :|...|..| .::.|.:.|..|.:|....|.|
 Worm    74 MPGYAFQGF-QIKKLFLRNNGLRSFHPNTFTGNLENSLEELEIRGNYIDGIPQSGVSILKQLKIL 137

  Fly   112 --------------------ASNLMSLFLGYNRLKDIPKNIFLGADNLATLHLQGNQLKQLGNHS 156
                                ..:|:.|.|..|.|..|.....||.:||:.|.|..|.|.::.:.:
 Worm   138 SLPDNLIEYVQDNAFLSYHSRDSLLKLDLSANNLTAIHPTGLLGLENLSQLSLDKNLLSEIPSQA 202

  Fly   157 FHALKEVKELSLAENQLEQISLGVFSGMRKLMDLNLAGNRLDALPRGVFDRNLNLTKLNLARNRF 221
            ...:..:::|||..|::..||..... :..|..|:|..|::..:|...|.....|:.|.|..|..
 Worm   203 LENIPSLEDLSLGVNRIHTISRNSLP-LPNLKSLSLEVNQIRLIPSDSFSETPLLSYLYLGNNLL 266

  Fly   222 TAFESEL------LKLQPV-----FTQLDISGNI-FQELTLNFTMLDVAIAHSCDLRRLTVYGV- 273
            |:.::.:      ||:..:     .|.:..:|.: .|:..|...:|  |..|:..|.||.::..
 Worm   267 TSIDASMFLHIGGLKVLSMSNNKDITSIQANGKLSVQQFKLCICIL--AFQHAPSLIRLELFDCS 329

  Fly   274 IHELDLHNNSLREMPHIPLAANVSSLDLSHNPLGNLQGNPLRRFTSLLRLNLSATGAHELPEGLF 338
            |..::  ..||:::.||.:      :.||.|.:..:..:.......|..|:||....:.:.:..|
 Worm   330 ISRIE--PKSLQKVQHIQV------ILLSRNQITRISHDTFSNLPELSELDLSGNSINAVDDFAF 386

  Fly   339 KKQSHLQMLDISGNSIYSL-KITIFDSL------KALQYFYFQQNNWNCDFLQLLMSSFVKRKDI 396
            .:...|..||:|.|.:.|| ...|:|||      ...:....|.|.|.||            ||:
 Worm   387 SQLPMLTSLDLSSNRLESLPSNVIYDSLMQKKTSPVQRKLSIQNNPWRCD------------KDL 439

  Fly   397 SFME-------DIT-----APELVDDYVDGIACWYESD 422
            .::.       |:|     :|.        ..||..|:
 Worm   440 MWLRKWLRDNGDVTTAASNSPP--------AKCWTPSN 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alrm	NP_651393.1	LRR_RI	84..354	CDD:238064	69/335 (21%)
		LRR_8	91..149	CDD:290566	19/110 (17%)
		leucine-rich repeat	91..114	CDD:275380	6/75 (8%)
		leucine-rich repeat	115..138	CDD:275380	8/22 (36%)
		LRR_8	138..197	CDD:290566	16/58 (28%)
		leucine-rich repeat	139..162	CDD:275380	5/22 (23%)
		leucine-rich repeat	163..186	CDD:275380	6/22 (27%)
		LRR_8	185..243	CDD:290566	14/68 (21%)
		leucine-rich repeat	187..210	CDD:275380	6/22 (27%)
		leucine-rich repeat	211..283	CDD:275380	18/84 (21%)
		leucine-rich repeat	284..319	CDD:275380	6/34 (18%)
		LRR_8	318..377	CDD:290566	17/65 (26%)
		leucine-rich repeat	320..343	CDD:275380	5/22 (23%)
		leucine-rich repeat	344..365	CDD:275380	9/21 (43%)
lron-1	NP_510424.4	PRK15370	<58..>289	CDD:185268	47/232 (20%)
		leucine-rich repeat	85..109	CDD:275380	6/23 (26%)
		leucine-rich repeat	110..133	CDD:275380	0/22 (0%)
		leucine-rich repeat	134..157	CDD:275380	0/22 (0%)
		leucine-rich repeat	161..184	CDD:275380	8/22 (36%)
		leucine-rich repeat	185..208	CDD:275380	5/22 (23%)
		leucine-rich repeat	209..231	CDD:275380	6/22 (27%)
		leucine-rich repeat	232..255	CDD:275380	6/22 (27%)
		leucine-rich repeat	256..279	CDD:275380	5/22 (23%)
		leucine-rich repeat	280..319	CDD:275380	9/40 (23%)
		leucine-rich repeat	320..343	CDD:275380	6/24 (25%)
		LRR_8	343..402	CDD:338972	15/64 (23%)
		leucine-rich repeat	344..367	CDD:275380	4/28 (14%)
		leucine-rich repeat	368..391	CDD:275380	5/22 (23%)
		leucine-rich repeat	392..410	CDD:275380	7/17 (41%)
		leucine-rich repeat	414..435	CDD:275378	4/20 (20%)
		LRRCT	431..>472	CDD:214507	12/59 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45617
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100