DRSC/TRiP Functional Genomics Resources

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Protein Alignment alrm and lingo4a

DIOPT Version :9

Sequence 1:NP_651393.1 Gene:alrm / 43074 FlyBaseID:FBgn0039332 Length:471 Species:Drosophila melanogaster
Sequence 2:NP_001076447.1 Gene:lingo4a / 100005227 ZFINID:ZDB-GENE-060503-275 Length:618 Species:Danio rerio


Alignment Length:392 Identity:103/392 - (26%)
Similarity:164/392 - (41%) Gaps:58/392 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 WWLLSLQVVLILPPSYHLATPSSGSGQLR-----RLWLQDHCSAGICTNVVIGRSDYVILSQAPI 64
            ||::...||         ...:||....|     :|.|.| ||:...:.|..|..|         
Zfish    26 WWVVLQWVV---------GVATSGPCAQRCDCSPKLPLVD-CSSQQLSAVPEGVPD--------- 71

  Fly    65 GGTTMLTFLNSSIAKIPHLLFDTFPDLQVLRMENCSLETFEKPQFEGASNLMSLFLGYNRLKDIP 129
             .|.:|....:.:..:....|.:...|:.|.:....|...|...|.|..||::|.|..||||.||
Zfish    72 -ATQVLNLTYNHLKTLSSRQFFSLRQLRELDLSANMLTVIEVEAFVGLQNLITLRLSRNRLKIIP 135

  Fly   130 KNIFLGADNLATLHLQGNQLKQLGNHSFHALKEVKELSLAENQLEQISLGVFSGMRKLMDLNLAG 194
            ...|.|..|:..|.:..|::..|.:..|..:..:::|..:||.|..||...|||:..|::|.|..
Zfish   136 VGAFSGLPNVQFLDISENEILVLLDDMFGEMPSLQKLEASENDLVFISNRAFSGLPNLLELRLER 200

  Fly   195 NRLDALPRGVFDRNLNLTKLNLARNRFTAFESELLKLQPVFTQLDISGNIFQELTLNFTMLDVAI 259
            ..|..:|...|.|...|..|...|...||                :..|.|::|.   .:.|:.:
Zfish   201 CNLTTVPSEAFSRLTGLQHLRFCRLGLTA----------------LPNNSFRQLQ---RLQDLHV 246

  Fly   260 AHSCDLRRLTVYGVI----HELDLHNNSLREMPHIPL--AANVSSLDLSHNP----LGNLQGNPL 314
            :....|..|.|..:|    ..|.|.:.:|..:|:.||  ...:..||||:||    |..|.|:.|
Zfish   247 SRCPWLHTLAVNSLIGLNLTSLTLSHCNLSAVPYAPLHHLVYLRYLDLSYNPITTVLSGLLGDLL 311

  Fly   315 RRFTSLLRLNLSATGAHELPEGLFKKQSHLQMLDISGNSIYSLKITIFDSLKALQYFYFQQNNWN 379
            |    |..|:|.:||...:..|.|:..:..::|::|.|.:.:|:.:.|.::.:|:......|...
Zfish   312 R----LQELHLVSTGLLHVESGAFRNLAFFRLLNVSDNRLVTLEESAFHAVGSLEVLRLDGNPLA 372

  Fly   380 CD 381
            ||
Zfish   373 CD 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alrmNP_651393.1 LRR_RI 84..354 CDD:238064 80/279 (29%)
LRR_8 91..149 CDD:290566 21/57 (37%)
leucine-rich repeat 91..114 CDD:275380 6/22 (27%)
leucine-rich repeat 115..138 CDD:275380 11/22 (50%)
LRR_8 138..197 CDD:290566 17/58 (29%)
leucine-rich repeat 139..162 CDD:275380 4/22 (18%)
leucine-rich repeat 163..186 CDD:275380 9/22 (41%)
LRR_8 185..243 CDD:290566 12/57 (21%)
leucine-rich repeat 187..210 CDD:275380 7/22 (32%)
leucine-rich repeat 211..283 CDD:275380 15/75 (20%)
leucine-rich repeat 284..319 CDD:275380 15/40 (38%)
LRR_8 318..377 CDD:290566 13/58 (22%)
leucine-rich repeat 320..343 CDD:275380 7/22 (32%)
leucine-rich repeat 344..365 CDD:275380 5/20 (25%)
lingo4aNP_001076447.1 LRRNT 41..70 CDD:214470 8/29 (28%)
leucine-rich repeat 52..72 CDD:275380 8/30 (27%)
leucine-rich repeat 73..96 CDD:275380 3/22 (14%)
LRR_RI 88..380 CDD:238064 86/310 (28%)
LRR_8 95..155 CDD:290566 21/59 (36%)
leucine-rich repeat 97..120 CDD:275380 6/22 (27%)
leucine-rich repeat 121..144 CDD:275380 11/22 (50%)
leucine-rich repeat 145..168 CDD:275380 4/22 (18%)
leucine-rich repeat 169..192 CDD:275380 9/22 (41%)
LRR_8 191..250 CDD:290566 16/77 (21%)
leucine-rich repeat 193..216 CDD:275380 7/22 (32%)
leucine-rich repeat 217..240 CDD:275380 8/41 (20%)
leucine-rich repeat 241..288 CDD:275380 11/46 (24%)
LRR_8 264..323 CDD:290566 21/62 (34%)
leucine-rich repeat 289..310 CDD:275380 9/20 (45%)
LRR_8 312..371 CDD:290566 15/62 (24%)
leucine-rich repeat 313..336 CDD:275380 7/22 (32%)
leucine-rich repeat 337..356 CDD:275380 4/18 (22%)
I-set 428..512 CDD:254352
Ig 439..512 CDD:299845
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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