Protein Alignment tobi and Ganc

DIOPT Version :10

• Sequence 1: NP_651391.1
• Gene: tobi / 43072
• FlyBaseID: FBgn0261575
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_766260.2
• Gene: Ganc / 76051
• MGIID: 1923301
• Length: 913
• Species: Mus musculus
• Alignment Length: 611
• Identity: 135/611 - (22%)
• Similarity: 219/611 - (35%)
• Gaps: 140/611 - (22%)

  Fly   131 STHWFSGPEQKQHYWPVERQRHSNYSYLPKELDNFGVGERYWLNGDGVFLY-------VESNTPL 188
            |.|.|      :|.:.:.:...|:      :|.|...|:.|.|....|:.|       :..:.|.
Mouse   217 SLHGF------EHLYGIPQHAESH------QLKNTRDGDAYRLYNLDVYGYQVHDKMGIYGSVPY 269

  Fly   189 FIDQNSAAYPDQLCLSAISAL---PYDPRVTSAKFVYHVAVAKDAKAAHRYAVKT---------- 240
            .:............|:|...|   ..:|.|.     |.:.....|.|..:...:|
Mouse   270 LLAHKQGRTVGIFWLNASETLVEINTEPAVE-----YTLTQMGPAAAKQKVRCRTDVHWMSESGI 329

  Fly   241 ----FLGQPT--------GYPDERMVMHPVWS------TWALYKAEVSDDVVRDFAKQILDNGFN 287
                .|..||        .|......|.|::|      .|   ..|...||      :.:|.||:
Mouse   330 IDVFLLTGPTPADVFKQYSYITGTQAMPPLFSLGYHQCRW---NYEDEQDV------KAVDAGFD 385

  Fly   288 NSQLEIDDDWEDCYGA-----MTFRKNKFPDSKTLTDDLKALGFRVTLWIHPFIN-NNCTAIYDE 346
            ...:..|..|.|....     .|:.|.:|.:.|.:.:.|::...::.:...|.|. :....:|.:
Mouse   386 EHDIPYDVMWLDIEHTEDKKYFTWDKKRFANPKRMQELLRSKKRKLVVISDPHIKVDPDYTVYAQ 450

  Fly   347 AKSKGYLVLDHEGSS-DTQWWNSKPKDAAILDFTKTEVQEWFSKRLKRLQDEDGIDSFKFDAGET 410
            ||.:|:.|.:.||.. :...|   |..::.||||..:|:||:|          .:.:|....|.|
Mouse   451 AKEQGFFVKNPEGGDFEGVCW---PGLSSYLDFTNPKVREWYS----------SLFAFPVYQGST 502

  Fly   411 SWL--------PS---DPVLQASSSMV-------TPLQAVGDYVRTVAAFGDMVEVRSAQNTQDQ 457
            ..|        ||   .|.|....|.|       ..|..:..:.:.:|....::: ||  ..:::
Mouse   503 DILFLWNDMNEPSVFRGPELTMHKSAVHYGDWEHRELHNIYGFYQQMATAEGLIQ-RS--KGKER 564

  Fly   458 PIF--------------VRIVDKDSEWGWNNGLLTLISSMLQMNLNGYPFVLPDMIG--GNGYYE 506
            |..              |...|..:||.:   |...|..:|.::::|..|...|:.|  ||
Mouse   565 PFVLSRSFFAGSQKYGAVWTGDNKAEWSY---LKISIPMLLTLSVSGISFCGADVGGFIGN---- 622

  Fly   507 KPPTKELFLRWLQANVFMPALQFSFV-------PWNFDDEAIAISKNFTALHATYTPYIMKLFKR 564
              |..||.:||.||..:.|..:....       ||.|.:|...:.:..........||:..||..
Mouse   623 --PEAELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEYTQLIREAIRQRYALLPYLYSLFYH 685

  Fly   565 AVDSGEPVNVPLWWIAPTDEVAQSIYDEFLLGEDIIAAPVVVEGATKRDIYLPEGE--WQDGNSD 627
            ...|.:||..|||...|.|....::.||::||..::..||........|::||..:  |.|..:.
Mouse   686 THVSSQPVMRPLWVEYPDDLETFAVEDEYMLGSALLVHPVTDPQTATIDVFLPGSDEVWYDSKTF 750

  Fly   628 QVYTGPTWVMDYAAPLDTLPYFLRVG 653
            ..:.|...| .....|||:|.|.|.|
Mouse   751 AYWKGGCTV-KIPVTLDTIPVFQRGG 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tobi	NP_651391.1	GH31_NET37	255..621	CDD:269878	98/421 (23%)
Ganc	NP_766260.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..188
		GH31_N	212..352	CDD:270212	26/151 (17%)
		GH31_GANC_GANAB_alpha	352..819	CDD:269889	109/459 (24%)